ES2145466T3 - Procedimiento para la purificacion del factor viii por cromatografia de afinidad. - Google Patents

Procedimiento para la purificacion del factor viii por cromatografia de afinidad.

Info

Publication number
ES2145466T3
ES2145466T3 ES96923903T ES96923903T ES2145466T3 ES 2145466 T3 ES2145466 T3 ES 2145466T3 ES 96923903 T ES96923903 T ES 96923903T ES 96923903 T ES96923903 T ES 96923903T ES 2145466 T3 ES2145466 T3 ES 2145466T3
Authority
ES
Spain
Prior art keywords
factor viii
purification
procedure
affinity chromatography
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96923903T
Other languages
English (en)
Inventor
Gert Muller-Berghaus
Bernd Potzsch
Horst Schwinn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAX PLANCK INST fur PHYSIOLOGI
Original Assignee
MAX PLANCK INST fur PHYSIOLOGI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8166248&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2145466(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MAX PLANCK INST fur PHYSIOLOGI filed Critical MAX PLANCK INST fur PHYSIOLOGI
Application granted granted Critical
Publication of ES2145466T3 publication Critical patent/ES2145466T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Abstract

LA INVENCION TRATA DE UN PROCEDIMIENTO PARA LA PURIFICACION POR CROMATOGRAFIA DE AFINIDAD DEL FACTOR VIII, CARACTERIZADO PORQUE SE PONE EN CONTACTO UN LIQUIDO BIOLOGICO QUE CONTIENE UN FACTOR VIII CON FACTOR VON - WILLEBRAND CELULAR INMOVILIZADO, O UN DERIVADO EN TALES CONDICIONES, QUE SE REALIZA UNA ADSORCION DEL FACTOR VIII EN EL FACTOR VON WILLEBRAND INMOVILIZADO O SU DERIVADO, SE QUITAN LAS IMPUREZAS Y SE ELUYE EL FACTOR VIII ADSORBIDO.
ES96923903T 1996-06-24 1996-06-24 Procedimiento para la purificacion del factor viii por cromatografia de afinidad. Expired - Lifetime ES2145466T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1996/002746 WO1997049730A1 (de) 1996-06-24 1996-06-24 Verfahren zur affinitätschromatographischen aufreinigung von faktor viii

Publications (1)

Publication Number Publication Date
ES2145466T3 true ES2145466T3 (es) 2000-07-01

Family

ID=8166248

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96923903T Expired - Lifetime ES2145466T3 (es) 1996-06-24 1996-06-24 Procedimiento para la purificacion del factor viii por cromatografia de afinidad.

Country Status (4)

Country Link
US (1) US6143179A (es)
EP (1) EP0910581B1 (es)
ES (1) ES2145466T3 (es)
WO (1) WO1997049730A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605222B1 (en) * 1998-05-20 2003-08-12 Baxter Aktiengesellschaft Method for producing a factor VIII/von Willebrand factor complex
JP6088435B2 (ja) 2010-12-15 2017-03-01 バクスアルタ ゲーエムベーハー 導電率グラディエントを用いる溶出液収集

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
US5610278A (en) * 1986-06-24 1997-03-11 Novo Nordisk A/S Process for producing a coagulation active complex of factor VIII fragments
US5200510A (en) * 1987-06-16 1993-04-06 Zymogenetics, Inc. Method for purifying factor viii:c, von willebrand factor and complexes thereof
US5605884A (en) * 1987-10-29 1997-02-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Factor VIII formulations in high ionic strength media
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
DE19521313A1 (de) * 1995-06-12 1996-12-19 Max Planck Inst Fuer Physiolog Verfahren zur affinitätschromatographischen Aufreinigung von Faktor VIII

Also Published As

Publication number Publication date
US6143179A (en) 2000-11-07
EP0910581A1 (de) 1999-04-28
WO1997049730A1 (de) 1997-12-31
EP0910581B1 (de) 2000-04-05

Similar Documents

Publication Publication Date Title
DK0746398T3 (da) Antistofrensning
ATE193839T1 (de) Reinigung von proteinen
ES2061642T3 (es) Metodo para la purificacion del factor viii:c de una mezcla de polipeptidos y otros constituyentes.
ES2122273T3 (es) Materiales que contienen compuestos organosilicicos utiles para dispositivos biomedicos.
NO894414L (no) Vaeskekromatografi ved anvendelse av mikroporoese, hule fibre.
DE69407558T2 (de) Adsorptionsmaterial enthaltend aktivierde Kohlenstofffaser und Polytetrafluorethylen
DE69417617D1 (de) Kolonne für Flüssigkeitschromatographie
DE69435170D1 (de) Extrakorporeale Vorrichtungen zur Adsorption durch Affinität
FI875589A0 (fi) HPLC-kolonni
DK0906122T3 (da) Aktiverede linkers og fremgangsmåde til at fremstille og oprense disse
DE69427848T2 (de) Unterstützungssystem zur Herstellung von Wörterbüchern
DE69023413T2 (de) Reinigung des Faktor-VIII-Komplexes unter Anwendung von Heparinaffinitätschromatographie.
ES2094182T3 (es) Sorcion de trialquil-arsinas.
ES2145466T3 (es) Procedimiento para la purificacion del factor viii por cromatografia de afinidad.
FR2541593B1 (fr) Support mineral poreux pour la purification et le fractionnement des macromolecules biologiques
ATE57936T1 (de) Material fuer affinitaetschromatographie und dessen anwendung zur trennung und reinigung von proteinischen antigenen von bakterien des genus bordetella.
DE69405894T2 (de) Schirm für Aquarium-Behälter
DE69922429D1 (de) Verwendung eines Adsorptionsmittels für die Trennung von halogenierten aromatischen Verbindungen und Trennungsverfahren unter Verwendung dieses Adsorptionsmittels
DE9410782U1 (de) Einrichtung zur Innenbeleuchtung von Behältnissen
SE8504887D0 (sv) Separationsmedel
KR940005284A (ko) 면역친화성 크로마토그래피에 의한 플라스미노겐 활성화제 억제제 2의 정제방법
DE69225215D1 (de) Trennungsmittel, welches gebundenes canalbumin enthält
DE29500922U1 (de) Lichtglas zur Vermeidung von PVC und anderen Kerzenhüllen für Grablaternen und andere
KR960023054A (ko) 재조합 인간 에리스로포이에틴의 정제 방법
AR245454A1 (es) Un procedimiento para fraccionar, concentrar o purificar proteinas.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 910581

Country of ref document: ES