ES2136599T3 - Tratamiento de las heridas utilizando peptidos biologicamente activos. - Google Patents
Tratamiento de las heridas utilizando peptidos biologicamente activos.Info
- Publication number
- ES2136599T3 ES2136599T3 ES91902831T ES91902831T ES2136599T3 ES 2136599 T3 ES2136599 T3 ES 2136599T3 ES 91902831 T ES91902831 T ES 91902831T ES 91902831 T ES91902831 T ES 91902831T ES 2136599 T3 ES2136599 T3 ES 2136599T3
- Authority
- ES
- Spain
- Prior art keywords
- biologically active
- wound treatment
- active peptides
- wound
- host
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Abstract
TRATAMIENTO DE HERIDAS QUE EMPLEA PEPTIDOS BIOLOGICAMENTE ACTIVOS. UN PROCESO PARA EL TRATAMIENTO DE UNA HERIDA EN UN HUESPED QUE COMPRENDE LA ADMINISTRACION AL HUESPED QUE TIENE UNA HERIDA DE, AL MENOS, UN PEPTIDO ANFIFILICO BIOLOGICAMENTE ACTIVO. EL PEPTIDO ES UN PEPTIDO CON FORMACION DE CANALES DE IONES Y SE ADMINISTRA EN UNA CANTIDAD EFICAZ PARA EL TRATAMIENTO DE LA HERIDA EN UN HUESPED.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/451,777 US5045531A (en) | 1989-12-18 | 1989-12-18 | Wound treatment employing biologically active ion channel forming peptides and proteins |
PCT/US1990/007440 WO1991008758A1 (en) | 1989-12-18 | 1990-12-12 | Wound treatment employing biologically active peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2136599T3 true ES2136599T3 (es) | 1999-12-01 |
Family
ID=23793638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91902831T Expired - Lifetime ES2136599T3 (es) | 1989-12-18 | 1990-12-12 | Tratamiento de las heridas utilizando peptidos biologicamente activos. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5045531A (es) |
EP (1) | EP0505497B1 (es) |
JP (1) | JPH05504566A (es) |
AT (1) | ATE181835T1 (es) |
CA (1) | CA2032059C (es) |
DE (1) | DE69033200T2 (es) |
DK (1) | DK0505497T3 (es) |
ES (1) | ES2136599T3 (es) |
GR (1) | GR3031459T3 (es) |
WO (1) | WO1991008758A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1327311C (en) * | 1987-07-06 | 1994-03-01 | Jesse M. Jaynes | Therapeutic antimicrobial polypeptides, their use and methods for preparation |
US5861478A (en) * | 1987-07-06 | 1999-01-19 | Helix Biomedix, Inc. | Lytic peptides |
WO1989000194A1 (en) | 1987-07-06 | 1989-01-12 | Louisiana State University Agricultural And Mechan | Inhibition of eucaryotic pathogens and neoplasms and stimulation of fibroblasts and lymphocytes with lytic peptides |
US5912231A (en) * | 1989-07-07 | 1999-06-15 | Scripps Clinic And Research Foundation | Substitution analogues of magainin peptides |
US5242902A (en) * | 1989-09-06 | 1993-09-07 | The Regents Of The University Of California | Defensin peptide compositions and methods for their use |
NZ237202A (en) * | 1990-02-23 | 1994-01-26 | Bristol Myers Squibb Co | Composition containing beta-lactam antibiotic and cationic oligopeptide |
AU648140B2 (en) * | 1991-02-01 | 1994-04-14 | Virtual Drug Development, Inc. | Reverse antimicrobial peptides and antimicrobial compositions |
WO1993001723A1 (en) * | 1991-07-25 | 1993-02-04 | Magainin Pharmaceuticals, Inc. | Prophylaxis and treatment of adverse oral conditions with biologically active peptides |
US5656456A (en) * | 1992-07-13 | 1997-08-12 | Bionebraska, Inc. | Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof |
ATE225801T1 (de) * | 1992-07-13 | 2002-10-15 | Bionebraska Inc | Verfahren zur modifizierung rekombinanter polypeptide |
US5593866A (en) * | 1992-08-21 | 1997-01-14 | The University Of British Columbia | Cationic peptides and method for production |
AU6251594A (en) * | 1993-02-26 | 1994-09-14 | Magainin Pharmaceuticals, Inc. | Treatment of cancerous growths with biologically active peptides and protease inhibitors |
US5733872A (en) * | 1993-03-12 | 1998-03-31 | Xoma Corporation | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
US5561107A (en) * | 1993-06-04 | 1996-10-01 | Demeter Biotechnologies, Ltd. | Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides |
US5968904A (en) * | 1993-06-04 | 1999-10-19 | Demegen, Inc. | Modified arginine containing lytic peptides and method of making the same by glyoxylation |
US5856178A (en) * | 1993-08-30 | 1999-01-05 | Utah State University | DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same |
KR960704524A (ko) * | 1993-10-25 | 1996-10-09 | 카롤 질레스피 | 디피신을 함유한 리포좀(liposomal defensins) |
AU1086595A (en) | 1993-11-08 | 1995-05-29 | Demeter Biotechnologies, Ltd. | Methylated lysine-rich lytic peptides and method of making same by reductive alkylation |
US6057291A (en) | 1995-06-02 | 2000-05-02 | University Of British Columbia | Antimicrobial cationic peptides |
FR2735983B1 (fr) | 1995-06-29 | 1997-12-05 | Centre Nat Rech Scient | Peptide permettant de modifier l'activite du systeme immunitaire humain ou animal |
US6191254B1 (en) | 1995-08-23 | 2001-02-20 | University Of British Columbia | Antimicrobial cationic peptides |
US6077826A (en) * | 1996-01-25 | 2000-06-20 | Kansas State University Research Foundation | Synthetic macromolecular channel assembly for transport of chloride ions through epithelium useful in treating cystic fibrosis |
JP4048565B2 (ja) * | 1996-04-23 | 2008-02-20 | 東レ株式会社 | 「抗ピロリ菌剤」 |
DE10051983A1 (de) * | 2000-10-20 | 2002-06-13 | Beate Kehrel | Inhibierung der pathogenen Wirkung oxidierter Proteine |
WO2005094423A2 (en) * | 2004-02-26 | 2005-10-13 | President And Fellows Of Harvard College | Selective inhibition of proteasomes of tuberculosis and other bacteria |
WO2009070564A2 (en) * | 2007-11-27 | 2009-06-04 | Macrochem Corporation | Compositions and methods for prevention of infection in transcutaneous osseointegrated implants |
US11174288B2 (en) | 2016-12-06 | 2021-11-16 | Northeastern University | Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4507230A (en) * | 1982-05-12 | 1985-03-26 | Research Corporation | Peptide synthesis reagents and method of use |
US4863899A (en) * | 1983-05-09 | 1989-09-05 | Todaro George J | Biologically active polypeptides |
US4734399A (en) * | 1985-08-06 | 1988-03-29 | Hoffmann-La Roche Inc. | Growth hormone releasing factor analogs |
US4810777A (en) * | 1987-03-04 | 1989-03-07 | The United States Of America As Represented By The Department Of Health And Human Services | Antimicrobial compounds |
DE3852636T2 (de) * | 1987-12-24 | 1995-05-04 | Gropep Pty Ltd | Peptid-analoge vom insulinähnlichen wachstums-faktor 1 (igf-1) oder faktor 2 (igf-2). |
US4962277A (en) * | 1988-12-09 | 1990-10-09 | Scripps Clinic And Research Foundation | Deletion analogues of magainin peptides |
US5073542A (en) * | 1989-06-07 | 1991-12-17 | Magainin Sciences Inc. | CPF peptide compositions and their use in inhibiting growth of target cells or a virus |
-
1989
- 1989-12-18 US US07/451,777 patent/US5045531A/en not_active Expired - Lifetime
-
1990
- 1990-12-12 JP JP91503265A patent/JPH05504566A/ja active Pending
- 1990-12-12 AT AT91902831T patent/ATE181835T1/de not_active IP Right Cessation
- 1990-12-12 CA CA002032059A patent/CA2032059C/en not_active Expired - Fee Related
- 1990-12-12 DE DE69033200T patent/DE69033200T2/de not_active Expired - Fee Related
- 1990-12-12 ES ES91902831T patent/ES2136599T3/es not_active Expired - Lifetime
- 1990-12-12 WO PCT/US1990/007440 patent/WO1991008758A1/en active IP Right Grant
- 1990-12-12 EP EP91902831A patent/EP0505497B1/en not_active Expired - Lifetime
- 1990-12-12 DK DK91902831T patent/DK0505497T3/da active
-
1994
- 1994-09-08 US US08/303,061 patent/USRE35492E/en not_active Expired - Lifetime
-
1999
- 1999-10-07 GR GR990402550T patent/GR3031459T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0505497A1 (en) | 1992-09-30 |
DE69033200D1 (de) | 1999-08-12 |
CA2032059A1 (en) | 1991-06-19 |
EP0505497B1 (en) | 1999-07-07 |
WO1991008758A1 (en) | 1991-06-27 |
CA2032059C (en) | 2003-02-25 |
EP0505497A4 (en) | 1993-09-08 |
DK0505497T3 (da) | 1999-11-22 |
US5045531A (en) | 1991-09-03 |
DE69033200T2 (de) | 2000-02-24 |
GR3031459T3 (en) | 2000-01-31 |
JPH05504566A (ja) | 1993-07-15 |
USRE35492E (en) | 1997-04-08 |
ATE181835T1 (de) | 1999-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2136599T3 (es) | Tratamiento de las heridas utilizando peptidos biologicamente activos. | |
RU94027680A (ru) | Паращитовидный гормон и ралоксифон для увеличения массы кости, фармацевтический состав и способ увеличения костной массы | |
ES2196640T3 (es) | Dispositivo terapeutico transdermico con capsaicina y analogos de capsaicina. | |
SE8501050D0 (sv) | Biologically active fragments of human antihemophilic factor and method for preparation thereof | |
GEP20002146B (en) | Therapeutic Peptide Derivatives | |
TR199801180T2 (xx) | Aneljestik etkiye sahip yeni bile�ikler. | |
DE69132688D1 (de) | Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin | |
ATE306931T1 (de) | Unterdrückung von veränderungen in zusammenhang mit beta-amyloid bei alzheimer | |
DE69116380D1 (de) | Pharmazeutische zubereitung zur behandlung verlängerter gerinnungszeit | |
DE69625682T2 (de) | Verfahren zur behandlung von entzündungen und zusammensetzungen dafür | |
ATE103804T1 (de) | Pharmazeutische praeparate. | |
DK403384D0 (da) | Enteralt effektivt, biologisk aktivt peptid- eller proteinmiddel ogfremgangsmaader til fremstilling deraf | |
TR199801184T2 (xx) | Analjezik tesirli yeni bile�ikler. | |
ATE107170T1 (de) | Zusammensetzung und behandelung mittels biologisch aktiven peptiden und bestimmten anionen. | |
DE69739482D1 (de) | Therapeutische formulierungen, die schlangen- und/oder insektengift enthalten, zur prophylaxe und therapie von neoplasmen | |
ATE306278T1 (de) | Behandlung von knochenleiden mit adrenomedullin | |
FR2549835B1 (fr) | Acides peneme-carboxyliques, leur preparation et leur utilisation therapeutique, notamment en tant qu'agents antibacteriens | |
BR9708037A (pt) | Método para o tratamento de abuso de substância | |
GEP20012377B (en) | Use of Trophoblastic Beta-1 Glycoprotein for Treating Auto-Immune Diseases and Method of Treatment These Diseases | |
RU94044795A (ru) | Способ лечения невралгии тройничного нерва | |
NO911470L (no) | Sammensetning og behandling med biologisk aktive peptiderog visse anioner. | |
RU93058154A (ru) | Способ лечения ранних приобретенных форм сифилиса | |
RU92016096A (ru) | Массажное устройство | |
GR1000913B (el) | Συνθεση & θεραπεια με βιολογικως δραστικα πεπτιδια & ορισμενα ανιοντα | |
RU94045317A (ru) | Способ лечения вилюйского энцефаломиелита |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 505497 Country of ref document: ES |