ES2133759T3 - Procedimiento para la preparacion de ciclohexil-azetidinonas. - Google Patents

Procedimiento para la preparacion de ciclohexil-azetidinonas.

Info

Publication number
ES2133759T3
ES2133759T3 ES95914304T ES95914304T ES2133759T3 ES 2133759 T3 ES2133759 T3 ES 2133759T3 ES 95914304 T ES95914304 T ES 95914304T ES 95914304 T ES95914304 T ES 95914304T ES 2133759 T3 ES2133759 T3 ES 2133759T3
Authority
ES
Spain
Prior art keywords
pct
preparation
image
cycllohexil
azetidinonas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95914304T
Other languages
English (en)
Inventor
Tino Rossi
Paola Zarantonello
John Russel Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline SpA
Original Assignee
Glaxo Wellcome SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome SpA filed Critical Glaxo Wellcome SpA
Application granted granted Critical
Publication of ES2133759T3 publication Critical patent/ES2133759T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE COMPUESTOS DE FORMULA (I) EN DONDE R{SUB,1} ES UN GRUPO HIDROXIL PROTECTOR EL CUAL INCLUYE REACCIONAR LA AZETIDINONA(II) CON (2S)-2-METOXICICLOHEXANO(III) HOMOQUIRAL O EL COMPLEJO DE LA MISMA FORMANDO UNA MOLECULA DE CLORURO ESTANNICO.
ES95914304T 1994-03-26 1995-03-23 Procedimiento para la preparacion de ciclohexil-azetidinonas. Expired - Lifetime ES2133759T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9406074A GB9406074D0 (en) 1994-03-26 1994-03-26 Chemical process

Publications (1)

Publication Number Publication Date
ES2133759T3 true ES2133759T3 (es) 1999-09-16

Family

ID=10752600

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95914304T Expired - Lifetime ES2133759T3 (es) 1994-03-26 1995-03-23 Procedimiento para la preparacion de ciclohexil-azetidinonas.

Country Status (11)

Country Link
US (1) US5817806A (es)
EP (1) EP0752984B1 (es)
JP (1) JPH09510966A (es)
AT (1) ATE180250T1 (es)
AU (1) AU2135895A (es)
DE (1) DE69509764T2 (es)
DK (1) DK0752984T3 (es)
ES (1) ES2133759T3 (es)
GB (1) GB9406074D0 (es)
GR (1) GR3031020T3 (es)
WO (1) WO1995026333A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631365A (en) 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
GB9516118D0 (en) * 1995-08-05 1995-10-04 Glaxo Spa Chemical process
JPH10168057A (ja) * 1996-12-12 1998-06-23 Takasago Internatl Corp シクロヘキシルアゼチジノン誘導体の製造法
WO2000063703A1 (en) * 1999-04-16 2000-10-26 Schering Corporation Use of azetidinone compounds
US20020151431A1 (en) * 2001-01-26 2002-10-17 Jeff Thornton Recovery method
SE523623C2 (sv) * 2001-01-26 2004-05-04 Sca Hygiene Prod Ab Återvinningsmetod för hydrofoba nitroxylradikaler
JP5137228B2 (ja) 2003-03-07 2013-02-06 メルク・シャープ・アンド・ドーム・コーポレーション 高コレステロール血症の処置のための置換アゼチジノン化合物、置換アゼチジノン処方物およびそれらの使用
ES2318274T3 (es) 2003-03-07 2009-05-01 Schering Corporation Compuestos de azetidinona sustituida, formulaciones y uso de los mismos para el tratamiento de hipercolesterolemia.
US7541398B2 (en) * 2005-01-03 2009-06-02 Board Of Regents, The University Of Texas System Method for transformation of conventional and commercially important polymers into durable and rechargeable antimicrobial polymeric materials
US20070062884A1 (en) * 2005-08-11 2007-03-22 Board Of Regents, The University Of Texas System N-halamines compounds as multifunctional additives
US7998886B2 (en) * 2005-10-24 2011-08-16 Milliken & Company Hindered amine treated textiles
US20070218562A1 (en) * 2006-03-20 2007-09-20 Shulong Li Color indicator for halamine treated fabric
US8486428B2 (en) * 2006-03-27 2013-07-16 Board Of Regents, The University Of Texas System Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles
US8211361B2 (en) * 2007-03-26 2012-07-03 Board Of Regents, The University Of Texas System N-halamine-based rechargeable biofilm-controlling tubular devices, method of making and using
US7858539B2 (en) * 2007-04-09 2010-12-28 Milliken & Company Processes for generating halamine compounds on textile substrates to produce antimicrobial finish
JP2011501732A (ja) * 2007-09-19 2011-01-13 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 着色剤ベースのｎ−ハラミン組成物並びに製造及び使用の方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ435990A3 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds
GB9104832D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9305853D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical compounds

Also Published As

Publication number Publication date
GB9406074D0 (en) 1994-05-18
DE69509764T2 (de) 1999-12-02
EP0752984A1 (en) 1997-01-15
GR3031020T3 (en) 1999-12-31
EP0752984B1 (en) 1999-05-19
WO1995026333A1 (en) 1995-10-05
AU2135895A (en) 1995-10-17
US5817806A (en) 1998-10-06
ATE180250T1 (de) 1999-06-15
DE69509764D1 (de) 1999-06-24
DK0752984T3 (da) 1999-11-29
JPH09510966A (ja) 1997-11-04

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