ES2133454T3 - Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles. - Google Patents

Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles.

Info

Publication number
ES2133454T3
ES2133454T3 ES94113877T ES94113877T ES2133454T3 ES 2133454 T3 ES2133454 T3 ES 2133454T3 ES 94113877 T ES94113877 T ES 94113877T ES 94113877 T ES94113877 T ES 94113877T ES 2133454 T3 ES2133454 T3 ES 2133454T3
Authority
ES
Spain
Prior art keywords
lysinates
effervescent
insoluble
mix
hardly soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94113877T
Other languages
English (en)
Inventor
Gerhard Dr Gergely
Thomas Dr Gergely
Irmgard Gergely
Stefan Dr Gergely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2133454T3 publication Critical patent/ES2133454T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/82—Acid flavourants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)

Abstract

LA MEZCLA EFERVESCENTE CONTIENE AL MENOS UNA SUSTANCIA ACTIVA FARMACEUTICA ACIDA, INSOLUBLE O DIFICILMENTE SOLUBLE EN FORMA DE SU SAL ALCALINA SOLUBLE O LISINATO, QUE EN UNA MEZCLA INTIMA ESTA PRESENTE CON EL COMPONENTE ALCALINO Y CON PREFERENCIA ENVUELTO CON LAS PARTICULAS DEL COMPONENTE ALCALINO DEL SISTEMA EFERVESCENTE, POR EJEMPLO BICARBONATO DE SODIO Y/O CARBONATO DE SODIO. AMBOS COMPONENTES PUEDEN TAMBIEN ESTAR PRESENTES DE FORMA PULVERIZADA FINA CON LA AYUDA DE UN AGLOMERANTE COMO GRANULADO. LA MEZCLA EFERVESCENTE CONTIENE ESPECIALMENTE SOBRE 100 PARTES DE SUSTANCIA ACTIVA AL MENOS 0,5, CON PREFERENCIA DESDE 1 HASTA 3 PARTES DE UN SURFACTANTE, ESPECIALMENTE DIOCTIL SULFOSUCINATO, Y/O AL MENOS 1, CON PREFERENCIA 3 HASTA 5 PARTES DE UN MEDIO AGLOMERANTE O MEDIO AUXILIAR DE SUSPENSION, EN PARTICULAR POLIVINIL PIRROLIDON. EL COMPONENTE ACIDO DEL SISTEMA EFERVESCENTE ESTA PASIVADO SUPERFICIALMENTE.
ES94113877T 1993-09-07 1994-09-05 Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles. Expired - Lifetime ES2133454T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH265293 1993-09-07

Publications (1)

Publication Number Publication Date
ES2133454T3 true ES2133454T3 (es) 1999-09-16

Family

ID=4238568

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94113877T Expired - Lifetime ES2133454T3 (es) 1993-09-07 1994-09-05 Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles.

Country Status (9)

Country Link
US (1) US5593693A (es)
EP (2) EP0642784B1 (es)
JP (1) JPH07223937A (es)
CN (1) CN1096279C (es)
AT (2) ATE219762T1 (es)
CA (1) CA2131515C (es)
DE (3) DE59408273D1 (es)
DK (1) DK0642784T3 (es)
ES (1) ES2133454T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283029B1 (it) * 1996-05-17 1998-04-03 Resa Farma Composizioni farmaceutiche a base di diclofenac
US7687542B2 (en) 1996-05-17 2010-03-30 Kowa Pharmaeuticals America, Inc. Rapidly bioavailable tablet and capsule formulations of diclofenac
US6974595B1 (en) 1996-05-17 2005-12-13 Proethic Pharmaceuticals, Inc. Pharmaceutical compositions based on Diclofenae
EP0962443B1 (de) * 1998-06-03 2003-04-23 Dr. Gergely & Co. Mit Alkali- bzw. Erdalkali-Ionen dotierte Zitronensäure
US6121215A (en) * 1999-08-27 2000-09-19 Phyzz, Inc. Foaming effervescent bath product
EP1082957B1 (de) * 1999-09-09 2003-04-23 Dr. Gergely & Co. Brausegranulat mit verzögerter Brausewirkung
US6432450B1 (en) 1999-09-09 2002-08-13 Gerhard Gergely Effervescent granules with delayed effervescent effect
FR2811531A1 (fr) * 2000-07-12 2002-01-18 Bionatec Produit pour le maintien d'objets decoratifs, procede de fabrication et d'utilisation dudit produit
JP2005521497A (ja) * 2002-03-25 2005-07-21 ワシントン・ユニバーシティ キメラ膵臓
AU2002350719A1 (en) * 2002-11-29 2004-06-23 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
EP1750677B1 (en) * 2004-05-28 2017-02-01 Imaginot Pty Ltd. Oral therapeutic compound delivery system
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
JO3352B1 (ar) 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
EP3263117A1 (en) * 2005-11-28 2018-01-03 Imaginot Pty Ltd. Oral therapeutic compound delivery system
US7939561B2 (en) 2006-02-07 2011-05-10 Apr Applied Pharma Research S.A. Blister packaging for acute pain regimens
US7700125B2 (en) 2006-02-07 2010-04-20 Kowa Pharmaceuticals America, Inc. Moisture resistant container systems for rapidly bioavailable dosage forms
BRPI0714423B1 (pt) 2006-07-12 2016-10-04 Purac Biochem Bv partícula grau alimentício revestida com ácido parcialmente neutralizado, produto alimentício ou bebida, método para preparação da referida partícula e uso de ácido policarboxílico
WO2013052019A1 (en) * 2011-08-19 2013-04-11 Mahmut Bilgic Production method for effervescent formulations comprising diclofenac
WO2013109222A1 (en) * 2012-01-18 2013-07-25 Mahmut Bilgic Formulations comprising diclofenac as the active agent
EP3037387A1 (en) * 2014-12-22 2016-06-29 Solvay SA Alkali metal bicarbonate particles with exceptional flowability

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076340B1 (de) * 1981-10-06 1984-08-15 Gerhard Dr. Gergely Verfahren zur Herstellung von gewünschtenfalls zu Brausetabletten verarbeitbaren Brausegranulaten
GB2148117B (en) * 1983-09-28 1987-10-21 Gergely Gerhard An effervescent composition suitable for effervescent tablets
US4678661A (en) * 1983-09-28 1987-07-07 Gerhard Gergely Effervescent composition and method of making same
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
DE3627475A1 (de) * 1986-06-26 1988-01-14 Gergely Gerhard Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung
DE3838431A1 (de) 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
US5064656A (en) * 1989-11-14 1991-11-12 Dr. Gergely & Co. Uncoated pharmaceutical reaction tablet
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5415870A (en) * 1991-07-01 1995-05-16 Gerhard Gergely Effervescent systems using reaction doping agents
DE9300886U1 (de) * 1993-01-22 1993-05-27 Ebinger, Klaus, 5000 Köln Stabförmige Magnetometer-Sonde

Also Published As

Publication number Publication date
US5593693A (en) 1997-01-14
ATE219762T1 (de) 2002-07-15
DE59408273D1 (de) 1999-06-24
CN1096279C (zh) 2002-12-18
DE9422239U1 (de) 1999-05-06
ATE180164T1 (de) 1999-06-15
EP0867426A3 (en) 1998-11-11
CA2131515C (en) 2006-08-29
JPH07223937A (ja) 1995-08-22
DK0642784T3 (da) 1999-11-22
EP0642784A1 (de) 1995-03-15
EP0867426B1 (de) 2002-06-26
EP0867426A2 (de) 1998-09-30
CN1107366A (zh) 1995-08-30
CA2131515A1 (en) 1995-03-08
DE59410143D1 (de) 2002-08-01
EP0642784B1 (de) 1999-05-19

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