ES2133428T3 - Fabricacion de amidas y peptidos, exenta de racemizacion, en presencia de cantidades cataliticas de un compuesto n-hidroxi. - Google Patents
Fabricacion de amidas y peptidos, exenta de racemizacion, en presencia de cantidades cataliticas de un compuesto n-hidroxi.Info
- Publication number
- ES2133428T3 ES2133428T3 ES94101784T ES94101784T ES2133428T3 ES 2133428 T3 ES2133428 T3 ES 2133428T3 ES 94101784 T ES94101784 T ES 94101784T ES 94101784 T ES94101784 T ES 94101784T ES 2133428 T3 ES2133428 T3 ES 2133428T3
- Authority
- ES
- Spain
- Prior art keywords
- amides
- peptides
- hydroxy compound
- racemization
- exempt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
- C07K1/084—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing nitrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Indole Compounds (AREA)
Abstract
PROCESO PARA LA OBTENCION DE AMIDAS Y DE PEPTIDOS POR TRANSFORMACION DE UN ACIDO CARBOXILICO CON UNA AMINA PRIMARIA O SECUNDARIA EN PRESENCIA DE UNA CARBODIIMIDA Y DE UNA CANTIDAD CATALITICA DE UN COMPUESTO DE HIDROXI-N.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH51893 | 1993-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2133428T3 true ES2133428T3 (es) | 1999-09-16 |
Family
ID=4188840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94101784T Expired - Lifetime ES2133428T3 (es) | 1993-02-19 | 1994-02-07 | Fabricacion de amidas y peptidos, exenta de racemizacion, en presencia de cantidades cataliticas de un compuesto n-hidroxi. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5536816A (es) |
EP (1) | EP0611774B1 (es) |
JP (1) | JP2524685B2 (es) |
CN (1) | CN1035873C (es) |
AT (1) | ATE180491T1 (es) |
DE (1) | DE59408292D1 (es) |
DK (1) | DK0611774T3 (es) |
ES (1) | ES2133428T3 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59408292D1 (de) * | 1993-02-19 | 1999-07-01 | Hoffmann La Roche | Racemisierungsfreie Herstellung von Amiden und Peptiden in Gegenwart katalytischer Mengen einer N-Hydroxy-Verbindung |
GB9424842D0 (en) * | 1994-12-09 | 1995-02-08 | British Tech Group | Pharmaceutical compositions |
EP0823424A1 (de) * | 1996-08-09 | 1998-02-11 | F. Hoffmann-La Roche Ag | Verfahren zur Herstellung von Chinargin |
US5914404A (en) * | 1996-08-09 | 1999-06-22 | Hoffmann-La Roche Inc. | Process for the preparation of quinargine |
DE59709770D1 (de) | 1996-12-11 | 2003-05-15 | Hoffmann La Roche | Verfahren zur Herstellung gemischter Anhydride |
CA2331330A1 (en) * | 1998-06-17 | 1999-12-23 | Magainin Pharmaceuticals, Inc. | Non-enzymatic chemical amidation process |
KR20020002480A (ko) * | 1999-03-17 | 2002-01-09 | 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 | 펩티드의 아실화법 및 신규한 아실화제 |
US6719080B1 (en) | 2000-01-10 | 2004-04-13 | The United States Of America As Represented By The Administrator Of The Environmental Protection Agency | Hydraulic hybrid vehicle |
CN1281624C (zh) | 2001-03-19 | 2006-10-25 | 藤森工业株式会社 | 凝血酶衍生物及其制造方法 |
US7423166B2 (en) * | 2001-12-13 | 2008-09-09 | Advanced Technology Materials, Inc. | Stabilized cyclosiloxanes for use as CVD precursors for low-dielectric constant thin films |
US7273921B2 (en) | 2002-09-25 | 2007-09-25 | Novo Nordisk A/S | Method for producing acylated peptides |
US20040077703A1 (en) * | 2002-10-02 | 2004-04-22 | Soll Mark D. | Nodulisporic acid derivative spot-on formulations for combating parasites |
CN103113177B (zh) * | 2013-02-06 | 2015-02-04 | 济南志合医药科技有限公司 | 一种酰胺的制备方法 |
CA2907454C (en) | 2013-03-21 | 2021-05-04 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
MX365465B (es) | 2013-03-21 | 2019-06-04 | Sanofi Aventis Deutschland | Sintesis de productos peptidicos que contienen imida ciclica. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2202613C3 (de) * | 1972-01-20 | 1974-06-20 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Verfahren zur Herstellung von Peptiden |
JP3866279B2 (ja) * | 1992-09-28 | 2007-01-10 | リサーチ コーポレイション テクノロジーズ,インコーポレイテッド | ペプチド連結用の新規な試薬 |
DE59408292D1 (de) * | 1993-02-19 | 1999-07-01 | Hoffmann La Roche | Racemisierungsfreie Herstellung von Amiden und Peptiden in Gegenwart katalytischer Mengen einer N-Hydroxy-Verbindung |
-
1994
- 1994-02-07 DE DE59408292T patent/DE59408292D1/de not_active Expired - Fee Related
- 1994-02-07 AT AT94101784T patent/ATE180491T1/de not_active IP Right Cessation
- 1994-02-07 DK DK94101784T patent/DK0611774T3/da not_active Application Discontinuation
- 1994-02-07 EP EP94101784A patent/EP0611774B1/de not_active Revoked
- 1994-02-07 ES ES94101784T patent/ES2133428T3/es not_active Expired - Lifetime
- 1994-02-15 US US08/196,750 patent/US5536816A/en not_active Expired - Fee Related
- 1994-02-15 JP JP6039301A patent/JP2524685B2/ja not_active Expired - Lifetime
- 1994-02-18 CN CN94101380A patent/CN1035873C/zh not_active Expired - Fee Related
-
1996
- 1996-02-23 US US08/606,104 patent/US5750649A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2524685B2 (ja) | 1996-08-14 |
DK0611774T3 (da) | 1999-11-15 |
JPH06256225A (ja) | 1994-09-13 |
EP0611774B1 (de) | 1999-05-26 |
EP0611774A1 (de) | 1994-08-24 |
US5750649A (en) | 1998-05-12 |
CN1111237A (zh) | 1995-11-08 |
DE59408292D1 (de) | 1999-07-01 |
CN1035873C (zh) | 1997-09-17 |
US5536816A (en) | 1996-07-16 |
ATE180491T1 (de) | 1999-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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