ES2131598T3 - Procedimiento para la obtencion de derivados del oxazol. - Google Patents

Procedimiento para la obtencion de derivados del oxazol.

Info

Publication number
ES2131598T3
ES2131598T3 ES94102191T ES94102191T ES2131598T3 ES 2131598 T3 ES2131598 T3 ES 2131598T3 ES 94102191 T ES94102191 T ES 94102191T ES 94102191 T ES94102191 T ES 94102191T ES 2131598 T3 ES2131598 T3 ES 2131598T3
Authority
ES
Spain
Prior art keywords
procedure
obtaining
oxazole derivatives
oxazoles
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94102191T
Other languages
English (en)
Inventor
Werner Bonrath
Reinhard Karge
Horst Pauling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2131598T3 publication Critical patent/ES2131598T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

SE DESCRIBE UN PROCESO PARA LA PRODUCCION DE 5-CIANO-4-ALQUILO PRECIPITADO-OXAZOL, PARA LO QUE EN CONDICIONES BASTANTE SUAVES SE DESHIDRATA EN PRESENCIA DE UNA SOLUCION, EL 5-CARBAMOIL-4-ALQUILO PRECIPITADO-OXAZOL CON CLORURO CIANURICO Y N,N-DIMETILFORMALDEHIDO.
ES94102191T 1993-02-25 1994-02-12 Procedimiento para la obtencion de derivados del oxazol. Expired - Lifetime ES2131598T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH57893 1993-02-25

Publications (1)

Publication Number Publication Date
ES2131598T3 true ES2131598T3 (es) 1999-08-01

Family

ID=4190248

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94102191T Expired - Lifetime ES2131598T3 (es) 1993-02-25 1994-02-12 Procedimiento para la obtencion de derivados del oxazol.

Country Status (8)

Country Link
US (1) US5502212A (es)
EP (1) EP0612736B1 (es)
JP (1) JP3622991B2 (es)
CN (1) CN1043890C (es)
AT (1) ATE178896T1 (es)
DE (1) DE59408098D1 (es)
DK (1) DK0612736T3 (es)
ES (1) ES2131598T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5910594A (en) * 1997-02-13 1999-06-08 Roche Vitamins Inc. Process for the manufacture of 5-cyano-4-lower alkyl-oxazoles
US6265579B1 (en) * 1999-10-29 2001-07-24 Salsbury Chemicals, Inc. Process for preparing piperazine-substituted aliphatic carboxylates
EP1380578A1 (en) * 2001-04-19 2004-01-14 Ono Pharmaceutical Co., Ltd. Process for producing nitrile compound
US8916715B2 (en) 2011-06-20 2014-12-23 Dsm Ip Assets B.V. Process for 4-methyloxazole-5-carboxamide
CN102424658B (zh) * 2011-10-31 2015-03-25 聊城大学 一种苯二腈或取代苯二腈的合成方法
CN104203930A (zh) * 2012-04-25 2014-12-10 帝斯曼知识产权资产管理有限公司 合成4-甲基噁唑-5-甲酰胺的方法
CN116075498A (zh) * 2020-08-06 2023-05-05 帝斯曼知识产权资产管理有限公司 制备噁唑化合物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH449623A (de) * 1963-05-22 1968-01-15 Hoffmann La Roche Verfahren zur Herstellung von 4-Alkyl-5-cyan-oxazolen
US4026901A (en) * 1975-04-30 1977-05-31 Hoffmann-La Roche Inc. Conversion of 4-lower alkyloxazole-5-carboxamide to 4-lower alkyl-5-cyanooxazoles
US4093654A (en) * 1977-03-31 1978-06-06 Hoffmann-La Roche Inc. Production of pyridoxine intermediates from diketene
CA1122220A (en) * 1978-11-02 1982-04-20 Hans Hoffmann-Paquotte Process for the manufacture of an oxazole
EP0224706A1 (de) * 1985-11-01 1987-06-10 F. Hoffmann-La Roche Ag Verfahren zur Herstellung eines Oxazols
US5214162A (en) * 1990-12-21 1993-05-25 Hoffman-La Roche Inc. Process for manufacturing 5-cyano-4-lower alkyloxazoles

Also Published As

Publication number Publication date
US5502212A (en) 1996-03-26
DE59408098D1 (de) 1999-05-20
ATE178896T1 (de) 1999-04-15
EP0612736B1 (de) 1999-04-14
JPH072806A (ja) 1995-01-06
JP3622991B2 (ja) 2005-02-23
EP0612736A1 (de) 1994-08-31
DK0612736T3 (da) 1999-10-25
CN1104213A (zh) 1995-06-28
CN1043890C (zh) 1999-06-30

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