ES2126516B1 - Glicoproteina para proteccion de liposomas. - Google Patents

Glicoproteina para proteccion de liposomas.

Info

Publication number
ES2126516B1
ES2126516B1 ES009700784A ES9700784A ES2126516B1 ES 2126516 B1 ES2126516 B1 ES 2126516B1 ES 009700784 A ES009700784 A ES 009700784A ES 9700784 A ES9700784 A ES 9700784A ES 2126516 B1 ES2126516 B1 ES 2126516B1
Authority
ES
Spain
Prior art keywords
glycoprotein
protein
protection
liposome
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES009700784A
Other languages
English (en)
Other versions
ES2126516A1 (es
Inventor
De Ferrer Nuria Bozal
Sanchez Jesus Guinea
Recovenir Encarna Tudela
Cordoba Francisco Congregado
Juez Jose Luis Parra
La Maza Ribera Alfonso De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitat Autonoma de Barcelona UAB
Universitat de Barcelona UB
Original Assignee
Universitat Autonoma de Barcelona UAB
Universitat de Barcelona UB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitat Autonoma de Barcelona UAB, Universitat de Barcelona UB filed Critical Universitat Autonoma de Barcelona UAB
Priority to ES009700784A priority Critical patent/ES2126516B1/es
Priority to AU65006/98A priority patent/AU6500698A/en
Priority to PCT/ES1998/000074 priority patent/WO1998042731A1/es
Publication of ES2126516A1 publication Critical patent/ES2126516A1/es
Application granted granted Critical
Publication of ES2126516B1 publication Critical patent/ES2126516B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Glicoproteína para protección de liposomas. Nueva glicoproteína con un 14% de carbohidrato y un 86% de proteína; la parte glicídica tiene una relación molar de glucosa: galactosa: N-acetilglucosamina: N-acetilgalactosamina de 1.00 : 0.14 : 0.13 : 0.33; y la parte proteica tiene la siguiente composición de aminoácidos: ácido aspártico, 7.87; treonina, 10.6; serina, 8.03; ácido glutámico, 7.99; prolina, 4.12; glicina, 8.42; alanina, 11.04; valina, 5.36; metionina, 1.86; isoleucina, 2.91; leucina, 4.80; tirosina, l.,58; fenilalanina, 2.61; histidina, 13.86; lisina, 4.87; y arginina, 4.0. Se obtiene por cultivo de la nueva especie bacteriana Pseudoalteromonas antarctica CECT4664. Es útil para el recubrimiento de liposomas aumentando su estabilidad frente a factores externo tales como tensioactivos, con la ventaja adicional de actuar también como crioprotector.
ES009700784A 1997-03-26 1997-03-26 Glicoproteina para proteccion de liposomas. Expired - Fee Related ES2126516B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES009700784A ES2126516B1 (es) 1997-03-26 1997-03-26 Glicoproteina para proteccion de liposomas.
AU65006/98A AU6500698A (en) 1997-03-26 1998-03-25 Glycoprotein for the protection of liposomes
PCT/ES1998/000074 WO1998042731A1 (es) 1997-03-26 1998-03-25 Glicoproteina para proteccion de liposomas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009700784A ES2126516B1 (es) 1997-03-26 1997-03-26 Glicoproteina para proteccion de liposomas.

Publications (2)

Publication Number Publication Date
ES2126516A1 ES2126516A1 (es) 1999-03-16
ES2126516B1 true ES2126516B1 (es) 1999-12-01

Family

ID=8298939

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009700784A Expired - Fee Related ES2126516B1 (es) 1997-03-26 1997-03-26 Glicoproteina para proteccion de liposomas.

Country Status (3)

Country Link
AU (1) AU6500698A (es)
ES (1) ES2126516B1 (es)
WO (1) WO1998042731A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2181592B1 (es) * 2001-06-14 2003-11-01 Lipotec Sa Uso de glicoproteina para el tratamiento y re-epitelizacion de heridas

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796088A4 (en) * 1995-01-05 1998-12-09 Univ California PREVENTING LIPOSOME AND BIOLOGICAL CELL OUTFLOW DURING THERMOTROPIC PHASE TRANSITION

Also Published As

Publication number Publication date
AU6500698A (en) 1998-10-20
ES2126516A1 (es) 1999-03-16
WO1998042731A1 (es) 1998-10-01

Similar Documents

Publication Publication Date Title
ES2165492T3 (es) Profarmacos ciclicos de peptidos y acidos nucleicos de peptidos con estabilidad metabolica mejorada y permeabilidad de la membrana celular.
AU3003395A (en) Active calpain expressed by baculovirus
ATE390441T1 (de) Niedrigallergene proteinvarianten
CA2182970A1 (en) Lyophilized Stem Cell Factor Formulations
ES2273447T3 (es) Plantas transgenicas resistentes a insectos y procedimientos para mejorar la actividad frente a insectos.
DE69730218D1 (de) Fusogene liposomen
WO1998007745A3 (en) Compositions and methods for treating infections using analogues of indolicidin
AU4280600A (en) Supplement for restoring growth hormone levels
DK0464140T3 (da) Aktivt adhæsionspeptid
KR960031602A (ko) 유전자 조환에 의한 사람 인슐린 전구체의 제조 및 이를 이용한 인슐린의 제조 방법
ATE245999T1 (de) Aminosäurezusammensetzungen
AR021602A1 (es) Metodo y composiciones para minimizar la obstruccion por acumulacion de material biologico y coloidal
ES2126516B1 (es) Glicoproteina para proteccion de liposomas.
PL342578A1 (en) Deep-frozen article of food
WO2002102360A3 (en) Compositions based on branched chain amino acids for improving the myocardial ventricular function in patients suffering from diabetes
CA2143045A1 (en) Lactic-acid-containing cyclic depsipeptides having 18 ring atoms as endoparasiticidal agents, and process for their preparation
AU5690400A (en) Novel compounds
WO1993016087A3 (en) Amadori reaction compounds and products, process for their manufacture, and their use
ATE315577T1 (de) Neue aminosäuresequenzen, deren kodierende dns, antikörper dagegen und deren verwendungen
BR0012572A (pt) Processo para produção de l-aminoácidos de seus derivados racêmicos de n-acetil-d, l por dissociação de racemato enzimática por meio de enzimas isoladas, recombinantes
DK1296675T3 (da) Sammensætninger baseret på aminosyrer, egnet til behandling af hjertesvigt
AU1509097A (en) Proteoglycan (G 009) effective in enhancing antitumor immunity
EP0563383A4 (en) (ganoderma lucidium) iy009 which produces proteoglycan (g009) having effect of enhancing antitumor immunity
EP0740935A4 (en) STIMULATOR OF ANALGESIC ACTIVITY
RU94024392A (ru) Минерально-аминокислотный концентрат

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19990316

Kind code of ref document: A1

Effective date: 19990316

FD2A Announcement of lapse in spain

Effective date: 20170703