ES2124910T3 - Dispensador que contiene un agente hidrofobo. - Google Patents

Dispensador que contiene un agente hidrofobo.

Info

Publication number
ES2124910T3
ES2124910T3 ES94926618T ES94926618T ES2124910T3 ES 2124910 T3 ES2124910 T3 ES 2124910T3 ES 94926618 T ES94926618 T ES 94926618T ES 94926618 T ES94926618 T ES 94926618T ES 2124910 T3 ES2124910 T3 ES 2124910T3
Authority
ES
Spain
Prior art keywords
active agent
formulation
hydrophobic
delivery device
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94926618T
Other languages
English (en)
Inventor
Liang C Dong
Steven D Espinal
Patrick S-L Wong
George V Guittard
Lawrence G Hamel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2124910T3 publication Critical patent/ES2124910T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Packages (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA FORMULACION PARA EL SUMINISTRO DE AGENTES HIDROFOBOS ACTIVOS A UN MEDIO FLUIDO PARA SU USO MIENTRAS SE EVITA LA AGREGACION DE LOS AGENTES HIDROFOBOS EN EL MEDIO, EN DONDE LA FORMULACION CONTIENE UN AGENTE HIDROFOBO ACTIVO EN UNA CANTIDAD DE UN 50 % DEL PESO O MAS JUNTO CON UN ESTEARATO DE POLIOXIETILENO 40 Y UN DESINTEGRANTE. LA PRESENTE INVENCION TAMBIEN SE ORIENTA A UNA MEJORA EN UN DISPOSITIVO DE SUMINISTRO ACTIVADO POR UN FLUIDO (10) EL QUE EL DISPOSITIVO DE SUMINISTRO INCLUYE UN ALOJAMIENTO (12) QUE DEFINE UN COMPARTIMIENTO INTERNO (14), UNA FORMULACION DE UN AGENTE ACTIVO (15) DISPUESTA EN EL COMPARTIMIENTO, UN ELEMENTO DE SALIDA (13) DISPUESTO EN EL ALOJAMIENTO (12) PARA EL SUMINISTRO DE LA FORMULACION DEL AGENTE ACTIVO (15) DESDE EL DISPOSITIVO DE SUMINISTRO, UN MIEMBRO ACCIONADOR EXPANDIBLE ACTIVADO POR UN FLUIDO (16) DISPUESTO EN EL COMPARTIMIENTO, OPCIONALMENTE UNA CAPA DE SEPARACION COLOCADA ENTRE LA FORMULACION DEL AGENTE ACTIVO (15) Y ELMIEMBRO ACCIONADOR (16) Y OPCIONALMENTE UNA FORMULA UN SUBREVESTIMIENTO LUBRICANTE (18); EN EL QUE LA MEJORA CONSISTE EN UNA FORMULACION DE UN AGENTE ACTIVO (15) QUE CONTIENE UN AGENTE HIDROFOBO ACTIVO EN UNA CANTIDAD DE UN 50 % DEL PESO O MAS JUNTO CON ESTEARATO DE POLIOXIETILENO 40 Y UN DESINTEGRANTE.
ES94926618T 1993-08-31 1994-08-31 Dispensador que contiene un agente hidrofobo. Expired - Lifetime ES2124910T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11457393A 1993-08-31 1993-08-31

Publications (1)

Publication Number Publication Date
ES2124910T3 true ES2124910T3 (es) 1999-02-16

Family

ID=22356090

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94926618T Expired - Lifetime ES2124910T3 (es) 1993-08-31 1994-08-31 Dispensador que contiene un agente hidrofobo.

Country Status (10)

Country Link
EP (1) EP0716595B1 (es)
JP (1) JP4015184B2 (es)
AT (1) ATE173613T1 (es)
AU (1) AU7640294A (es)
CA (1) CA2165190C (es)
DE (1) DE69414863T2 (es)
DK (1) DK0716595T3 (es)
ES (1) ES2124910T3 (es)
WO (1) WO1995006460A1 (es)
ZA (1) ZA946663B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
DK1112060T3 (da) * 1998-09-09 2006-04-18 Alza Corp Doseringsform anvendende flydende formulering
ATE323493T1 (de) * 1998-11-02 2006-05-15 Alza Corp Gesteuerte freisetzung von antidepressiva
AU1238500A (en) * 1998-11-02 2000-05-22 Alza Corporation Controlled delivery of active agents
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
US9173847B2 (en) 2003-10-10 2015-11-03 Veloxis Pharmaceuticals A/S Tablet comprising a fibrate
EP1680091B1 (en) 2003-10-10 2017-05-31 Veloxis Pharmaceuticals A/S A solid dosage form comprising a fibrate
AU2004308973A1 (en) * 2003-12-23 2005-07-14 Alza Corporation Methods and dosage forms for increasing solubility of drug compositions for controlled delivery

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192550A (en) * 1990-05-07 1993-03-09 Alza Corporation Dosage form for treating central nervous system disorders

Also Published As

Publication number Publication date
EP0716595B1 (en) 1998-11-25
EP0716595A1 (en) 1996-06-19
ZA946663B (en) 1995-03-31
WO1995006460A1 (en) 1995-03-09
CA2165190A1 (en) 1995-03-09
ATE173613T1 (de) 1998-12-15
DK0716595T3 (da) 1999-08-09
CA2165190C (en) 2005-07-12
JP4015184B2 (ja) 2007-11-28
JPH09502182A (ja) 1997-03-04
DE69414863T2 (de) 1999-04-22
DE69414863D1 (de) 1999-01-07
AU7640294A (en) 1995-03-22

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