ES2123078T3 - Procedimiento para la preparacion de 5h-dibenz/b,f/azepin-5-carboxamida. - Google Patents

Procedimiento para la preparacion de 5h-dibenz/b,f/azepin-5-carboxamida.

Info

Publication number
ES2123078T3
ES2123078T3 ES94109605T ES94109605T ES2123078T3 ES 2123078 T3 ES2123078 T3 ES 2123078T3 ES 94109605 T ES94109605 T ES 94109605T ES 94109605 T ES94109605 T ES 94109605T ES 2123078 T3 ES2123078 T3 ES 2123078T3
Authority
ES
Spain
Prior art keywords
dibenz
carboxamide
azepin
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94109605T
Other languages
English (en)
Inventor
Rudolf Dr Eckardt
Hans-Joachim Dr Jansch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AWD Pharma GmbH and Co KG
Original Assignee
Arzneimittelwerk Dresden GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden GmbH filed Critical Arzneimittelwerk Dresden GmbH
Application granted granted Critical
Publication of ES2123078T3 publication Critical patent/ES2123078T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO SENCILLO PARA LA ELABORACION DE L 5H - DIBENZ/B,F/AZEPINA - 5 - CARBOXAMIDA (CARBAMAZEPINA). PUEDEN SER ELABORADOS DE FORMA VENTAJOSA MEDIANTE TRANSFORMACION DE IMINO ESTILBENO CON CIANATOS ALCALINOS EN ACIDO ACETICO, MEZCLAS DE ACIDO ACETICO - AGUA O MEZCLAS DE ACIDO ACETICO - ALCOHOL. LA CARBAMAZEPINA SIRVE PARA TRATAMIENTO DE UNA MULTIPLICIDAD DE ENFERMEDADES DEL SISTEMA NERVIOSO CENTRAL.
ES94109605T 1993-03-08 1994-06-22 Procedimiento para la preparacion de 5h-dibenz/b,f/azepin-5-carboxamida. Expired - Lifetime ES2123078T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4307181A DE4307181C1 (de) 1993-03-08 1993-03-08 Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid
EP94109605A EP0688768B1 (de) 1993-03-08 1994-06-22 Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid

Publications (1)

Publication Number Publication Date
ES2123078T3 true ES2123078T3 (es) 1999-01-01

Family

ID=25923720

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94109605T Expired - Lifetime ES2123078T3 (es) 1993-03-08 1994-06-22 Procedimiento para la preparacion de 5h-dibenz/b,f/azepin-5-carboxamida.

Country Status (4)

Country Link
EP (1) EP0688768B1 (es)
AT (1) ATE170514T1 (es)
DE (1) DE4307181C1 (es)
ES (1) ES2123078T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1272897B (it) * 1995-01-13 1997-07-01 I F C Iniziative Finanziaarie Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
EP1026158B1 (en) * 1999-02-08 2003-09-24 Max India Limited Process for the preparation of 5-carbamoyl-5H-dibenz(b,f)azepine
EP1513816A4 (en) * 2002-06-14 2009-12-16 Taro Pharmaceuticals Usa Inc PROCESS FOR THE PRODUCTION OF 5H-DIBENZ (B, F) AZEPINE-5-CARBOXAMIDE
CA2452588C (en) 2003-12-08 2015-05-19 Shire Pharmaceutical Development Inc. Methods for the treatment of bipolar disorder using carbamazepine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2948718A (en) * 1960-08-09 New n-heterocyclic compounds
GB1087174A (en) * 1965-04-05 1967-10-11 Allen & Hanburys Ltd Piperidine derivatives
GB1246606A (en) * 1969-04-28 1971-09-15 Starogardzkie Zakl Farma Dibenzo-azepine derivatives
DD101670A1 (es) * 1972-02-22 1973-11-12
BG21940A1 (en) * 1975-08-20 1979-12-12 Georgiev Method of obtaining of derivatives of 5- (carbamoyl)- dibenz (b, f) azepine
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
JPS5681565A (en) * 1979-10-30 1981-07-03 Ciba Geigy Ag Manufacture of nnheterocyclic compound
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DD298508A5 (de) * 1988-10-11 1992-02-27 Arzneimittelwerk Dresden Gmbh,De Verfahren zur herstellung von 5-carbamoyl-5h-dibenz/b,f/azepin
HU206321B (en) * 1989-10-16 1992-10-28 Alkaloida Vegyeszeti Gyar Improved process for producing 5-carbamoyl-5h-dibenz/b:f/azepine
DD297962A5 (de) * 1990-07-05 1992-01-30 �������@������������@��k�� Verfahren zur herstellung von 5-carbamoyl-5h-dibenz/b,f/azepin

Also Published As

Publication number Publication date
EP0688768A1 (de) 1995-12-27
DE4307181C1 (de) 1994-11-10
EP0688768B1 (de) 1998-09-02
ATE170514T1 (de) 1998-09-15

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