ES2121916T3 - Metodo mejorado para la preparacion de 3-amino-2-cloro-4-alquilpiridinas. - Google Patents

Metodo mejorado para la preparacion de 3-amino-2-cloro-4-alquilpiridinas.

Info

Publication number
ES2121916T3
ES2121916T3 ES93118542T ES93118542T ES2121916T3 ES 2121916 T3 ES2121916 T3 ES 2121916T3 ES 93118542 T ES93118542 T ES 93118542T ES 93118542 T ES93118542 T ES 93118542T ES 2121916 T3 ES2121916 T3 ES 2121916T3
Authority
ES
Spain
Prior art keywords
preparation
amino
piridines
chlorine
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93118542T
Other languages
English (en)
Inventor
Laurence John Nummy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BOEHRINGER INGELHEIM PHARMA, Boehringer Ingelheim Pharmaceuticals Inc filed Critical BOEHRINGER INGELHEIM PHARMA
Application granted granted Critical
Publication of ES2121916T3 publication Critical patent/ES2121916T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE UNA 3 RO CARBURO LINEAL, RAMIFICADO O CICLICO, O DESDE UNO A OCHO ATOMOS, OPCIONALMENTE SUSTITUIDOS POR UNO O MAS GRUPOS DE ESTABILIZACION DE ELECTRONES; UN PRODUCTO INTERMEDIO EN LA PREPARACION DE CIERTOS COMPUESTOS DE 5,11 B: 2'', 3'' AMIENTO DE INFECCION DE HIV.
ES93118542T 1992-11-18 1993-11-18 Metodo mejorado para la preparacion de 3-amino-2-cloro-4-alquilpiridinas. Expired - Lifetime ES2121916T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97796292A 1992-11-18 1992-11-18

Publications (1)

Publication Number Publication Date
ES2121916T3 true ES2121916T3 (es) 1998-12-16

Family

ID=25525683

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93118542T Expired - Lifetime ES2121916T3 (es) 1992-11-18 1993-11-18 Metodo mejorado para la preparacion de 3-amino-2-cloro-4-alquilpiridinas.

Country Status (5)

Country Link
EP (1) EP0598396B1 (es)
AT (1) ATE170512T1 (es)
DE (1) DE69320759T2 (es)
DK (1) DK0598396T3 (es)
ES (1) ES2121916T3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4333697A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen
ZA9710197B (en) * 1996-11-13 1999-05-12 Dow Agrosciences Llc N-arylsulfilimine compounds and their use as catalysts in the preparation of n-arylarylsulfonamide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172095A (en) * 1977-06-10 1979-10-23 Schering Corporation Novel synthesis of 3-amino-2-methylbenzotrifluoride and the intermediates thereof
US4480130A (en) * 1983-09-07 1984-10-30 Monsanto Company Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement
US4496765A (en) * 1983-09-07 1985-01-29 Monsanto Company Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
DE69215346T2 (de) * 1991-06-11 1997-04-30 Boehringer Ingelheim Pharma Verfahren zur herstellung von 3-amino-2-chloro-4-alkylpyridinen
US5200522A (en) * 1991-06-11 1993-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for preparing 3-amino-2-chloro-4-alkylpyridines

Also Published As

Publication number Publication date
ATE170512T1 (de) 1998-09-15
DK0598396T3 (da) 1998-11-23
DE69320759D1 (de) 1998-10-08
EP0598396B1 (en) 1998-09-02
EP0598396A1 (en) 1994-05-25
DE69320759T2 (de) 1999-03-25

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