ES2118481T3 - Procedimiento para la obtencion de 2-halogenopiridinaldehidos. - Google Patents
Procedimiento para la obtencion de 2-halogenopiridinaldehidos.Info
- Publication number
- ES2118481T3 ES2118481T3 ES95112442T ES95112442T ES2118481T3 ES 2118481 T3 ES2118481 T3 ES 2118481T3 ES 95112442 T ES95112442 T ES 95112442T ES 95112442 T ES95112442 T ES 95112442T ES 2118481 T3 ES2118481 T3 ES 2118481T3
- Authority
- ES
- Spain
- Prior art keywords
- obtaining
- halogenopiridinaldehyde
- procedure
- hydroxyiminoolefins
- halogenpiridines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001299 aldehydes Chemical group 0.000 abstract 2
- -1 AMINO Chemical class 0.000 abstract 1
- QQVDYSUDFZZPSU-UHFFFAOYSA-M chloromethylidene(dimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)=CCl QQVDYSUDFZZPSU-UHFFFAOYSA-M 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4429465A DE4429465A1 (de) | 1994-08-19 | 1994-08-19 | Verfahren zur Herstellung von 2-Halogenpyridinaldehyden und neue 2-Halogenpyridinaldehyde |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2118481T3 true ES2118481T3 (es) | 1998-09-16 |
Family
ID=6526101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95112442T Expired - Lifetime ES2118481T3 (es) | 1994-08-19 | 1995-08-08 | Procedimiento para la obtencion de 2-halogenopiridinaldehidos. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5708180A (OSRAM) |
| EP (1) | EP0702003B1 (OSRAM) |
| JP (1) | JPH0859619A (OSRAM) |
| CA (1) | CA2156230A1 (OSRAM) |
| DE (2) | DE4429465A1 (OSRAM) |
| ES (1) | ES2118481T3 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6737529B2 (en) * | 2002-03-07 | 2004-05-18 | Council Of Scientific And Industrial Research | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde |
| US6479664B1 (en) | 2002-03-18 | 2002-11-12 | Council Of Scientific And Industrial Research | Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde |
| DE60228045D1 (de) * | 2002-03-20 | 2008-09-18 | Council Scient Ind Res | Verfahren zur Herstellung von 2-Chlor-5-methylpyridin-3-carbaldehyd |
| DE102006033572A1 (de) | 2006-07-20 | 2008-01-24 | Bayer Cropscience Ag | N'-Cyano-N-halogenalkyl-imidamid Derivate |
| PL2069336T3 (pl) | 2006-09-07 | 2013-05-31 | Idorsia Pharmaceuticals Ltd | Pochodne pirydyn-4-ylu jako środki immunomodulujące |
| MX2009002234A (es) | 2006-09-08 | 2009-03-16 | Actelion Pharmaceuticals Ltd | Derivados de piridin-3-il como agentes inmunomoduladores. |
| WO2008114157A1 (en) | 2007-03-16 | 2008-09-25 | Actelion Pharmaceuticals Ltd | Amino- pyridine derivatives as s1p1 /edg1 receptor agonists |
| EP2262799B1 (en) * | 2008-03-06 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Pyridine compounds |
| DK2252609T3 (da) | 2008-03-07 | 2013-06-24 | Actelion Pharmaceuticals Ltd | Pyridin-2-yl-derivater som immunomodulerende midler |
| PT2454255E (pt) | 2009-07-16 | 2014-01-14 | Actelion Pharmaceuticals Ltd | Derivados de piridin-4-il como agonistas de s1/p1/edg1 |
| SI2665720T1 (sl) | 2011-01-19 | 2015-08-31 | Actelion Pharmaceuticals Ltd. | Derivati 2-metoksi-piridin-4-ila |
| US20140113824A1 (en) | 2011-05-10 | 2014-04-24 | Bayer Intellectual Property Gmbh | Bicyclic (thio)carbonylamidines |
| DK3298008T3 (da) | 2015-05-20 | 2020-02-10 | Idorsia Pharmaceuticals Ltd | Krystallinsk form af forbindelsen (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propan-1,2-diol |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2232326B1 (OSRAM) | 1973-06-05 | 1977-11-10 | Pfizer | |
| EP0021453B1 (en) | 1977-08-12 | 1985-04-10 | Imperial Chemical Industries Plc | 2-chloro-5-trichloromethylpyridine |
| US4279913A (en) | 1978-01-04 | 1981-07-21 | Merck & Co., Inc. | Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines |
| DE3314196A1 (de) | 1982-07-16 | 1983-09-29 | CIBA-GEIGY AG, 4002 Basel | Heterocyclylaether |
| EP0192060B1 (de) | 1985-02-04 | 1991-09-18 | Nihon Bayer Agrochem K.K. | Heterocyclische Verbindungen |
| US5001138B1 (en) * | 1985-02-04 | 1998-01-20 | Bayer Agrochem Kk | Heterocyclic compounds |
| US4757073A (en) | 1986-09-30 | 1988-07-12 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylipiperazin-1-yl) pyridines, compositions and use |
| WO1992022203A1 (en) * | 1991-06-12 | 1992-12-23 | E.I. Du Pont De Nemours And Company | Substituted pyridine herbicides |
| JPH0517475A (ja) | 1991-07-09 | 1993-01-26 | Sapporo Breweries Ltd | 新規な３，４−ジヒドロ−１，８−ナフチリジン誘導体及びそれを含有する抗気管支喘息薬 |
| US5508410A (en) * | 1993-11-30 | 1996-04-16 | Reilly Industries, Inc. | Process for preparing 2-halo-5-substituted pyridines |
-
1994
- 1994-08-19 DE DE4429465A patent/DE4429465A1/de not_active Withdrawn
-
1995
- 1995-08-08 EP EP95112442A patent/EP0702003B1/de not_active Expired - Lifetime
- 1995-08-08 DE DE59502572T patent/DE59502572D1/de not_active Expired - Fee Related
- 1995-08-08 ES ES95112442T patent/ES2118481T3/es not_active Expired - Lifetime
- 1995-08-16 CA CA002156230A patent/CA2156230A1/en not_active Abandoned
- 1995-08-16 JP JP7229616A patent/JPH0859619A/ja active Pending
-
1996
- 1996-11-27 US US08/758,625 patent/US5708180A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0702003A2 (de) | 1996-03-20 |
| DE59502572D1 (de) | 1998-07-23 |
| DE4429465A1 (de) | 1996-02-22 |
| EP0702003A3 (OSRAM) | 1996-03-27 |
| JPH0859619A (ja) | 1996-03-05 |
| EP0702003B1 (de) | 1998-06-17 |
| CA2156230A1 (en) | 1996-02-20 |
| US5708180A (en) | 1998-01-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT101627A (pt) | Polipeptideo trombopoietina isolado e substancialmente homogeneo, dna que o codifica e metodos recombinantes ou de sintese para a sua preparacao e purificacao | |
| ES2118481T3 (es) | Procedimiento para la obtencion de 2-halogenopiridinaldehidos. | |
| NO960772L (no) | Naftylforbindelser og fremgangsmåte for fremstilling derav, mellomprodukter og preparater | |
| FI953134L (fi) | Vesiliukoisia kondensaatiotuotteita, jotka muodostuvat aminoryhmiä sisältävistä yhdisteistä ja silloitusaineista, menetelmä niiden valmistamiseksi ja niiden käyttö | |
| DK0739898T3 (da) | Phosphononmoneosternukleinsyrer, fremgangsmåde til fremstilling deraf og anvendelse deraf | |
| MX9206306A (es) | Peptidos, procedimiento para su produccion y composicion farmaceutica que los contiene. | |
| FI922620A7 (fi) | Peptidijohdannainen, menetelmä sen valmistamiseksi, sitä sisältävä far maseuttinen valmiste ja menetelmä glaukooman hoitamiseksi | |
| FI951468L (fi) | Lipopeptidijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö | |
| DE59610469D1 (de) | Vorrichtung zur Verabreichung von Substanzen, insbesondere Inhalationspräparate | |
| MX9202748A (es) | Compuesto de arileter, proceso para su obtencion y composicion farmaceutica que los contiene. | |
| ID21955A (id) | Sistim identifikasi medan | |
| FI973195L (fi) | Hairuston uutteet, menetelmä niiden valmistamiseksi ja niiden käyttö | |
| FI963781A7 (fi) | Eristettyjä, MAGE-3-peräisiä peptidejä, jotka kompleksoivat HLA-A2-mol ekyylejä, ja niiden käyttöjä | |
| BR9501980A (pt) | Copolimeros,processo para sua preparação | |
| PT788310E (pt) | Metodo para inibir doencas nas plantas | |
| FI963646L (fi) | Haarautuneet polyoksa-alkyylimakromolekyylit, menetelmä niiden valmistamiseksi sekä niiden käytöt | |
| MX24890A (es) | Polipeptido sintetico, procedimiento par su preparacion y composicion farmaceutica que lo contiene. | |
| DE59005554D1 (de) | Messerzylinder. | |
| GR1001593B (el) | Διαλυτοι σακκοι. | |
| DE58909116D1 (de) | Gasflaschenventil. | |
| IT1232009B (it) | Impianto di essiccazione, particolarmente per legname | |
| DE58903972D1 (de) | Verpackungseinheit fuer zierpflanzen, insbesondere blumenstraeusse. | |
| BR9600779A (pt) | Benzenossulfoniluréias e -tioréias substituidas processo para sua preparação uso e medicamento | |
| ES2089091T3 (es) | Complejos que contienen acidos s(+)-fenilalcanoicos y acidos alfa-hidroalcanoicos. | |
| TR25392A (tr) | Oligomerik tiokarbonatlar bunlari yapmaya mahsus yöntemler ve bunlarin pestisidler ve koruyucu maddeler olarak kullanimlari. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 702003 Country of ref document: ES |