ES2118234T3 - Dispositivo para generar particulas inhalables de sustancias activas. - Google Patents

Dispositivo para generar particulas inhalables de sustancias activas.

Info

Publication number
ES2118234T3
ES2118234T3 ES93909948T ES93909948T ES2118234T3 ES 2118234 T3 ES2118234 T3 ES 2118234T3 ES 93909948 T ES93909948 T ES 93909948T ES 93909948 T ES93909948 T ES 93909948T ES 2118234 T3 ES2118234 T3 ES 2118234T3
Authority
ES
Spain
Prior art keywords
ring
active substance
shaped body
substance particles
face mill
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93909948T
Other languages
English (en)
Inventor
Helmut Heide
Bernhard Hugemann
Joachim Pabst
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GGU GESUNDHEITS UMWELTFORSCH
Original Assignee
GGU GESUNDHEITS UMWELTFORSCH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GGU GESUNDHEITS UMWELTFORSCH filed Critical GGU GESUNDHEITS UMWELTFORSCH
Application granted granted Critical
Publication of ES2118234T3 publication Critical patent/ES2118234T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • A61M2202/066Powder made from a compacted product by abrading

Abstract

UN DISPOSITIVO PARA LA GENERACION MECANICA DE PARTICULAS DE SUSTANCIA ACTIVA INHALABLE A PARTIR DE UN SUMINISTRO DE MEDICAMENTO CONSOLIDADO Y PARA LA GUIA DE LAS PARTICULAS DE SUSTANCIA ACTIVA AL TRACTO RESPIRATORIO ESTA CARACTERIZADO POR LA DISPOSICION DE UN FRESADO FRONTAL PARA LA GENERACION DE PARTICULAS DE SUSTANCIA ACTIVA, Y CONTRA EL CUAL LA PARTE FRONTAL DE UN SUMINISTRO DE MEDICAMENTO PUEDE SER PRESIONADO EN FORMA DE UN CUERPO CON PERFIL ANULAR. EL CUERPO PERFILADO DE MODO ANULAR FORMA EL PRINCIPIO DE UN TUBO DE INHALACION QUE TERMINA EN UNA PIEZA DE BOCA. LA CARCASA QUE INCLUYE EL CUERPO PERFILADO ANULAR Y EL FRESADO FRONTAL ESTAN PROVISTOS CON ABERTURAS DE ENTRADA DE AIRE EN LA ZONA DE CORTE DEL FRESADO FRONTAL. CONJUNTAMENTE CON LAS DEPRESIONES LOCALIZADAS ENTRE LAS PALETAS Y EL TUBO DE INHALACION, LAS ABERTURAS DE ENTRADA DE AIRE FORMAN UN CANAL DE AIRE QUE GUIA A LA PIEZA DE BOCA.
ES93909948T 1992-05-29 1993-05-11 Dispositivo para generar particulas inhalables de sustancias activas. Expired - Lifetime ES2118234T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4217787 1992-05-29

Publications (1)

Publication Number Publication Date
ES2118234T3 true ES2118234T3 (es) 1998-09-16

Family

ID=6459994

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93909948T Expired - Lifetime ES2118234T3 (es) 1992-05-29 1993-05-11 Dispositivo para generar particulas inhalables de sustancias activas.

Country Status (11)

Country Link
US (1) US5673685A (es)
EP (1) EP0642366B1 (es)
AT (1) ATE158951T1 (es)
AU (1) AU686560B2 (es)
CA (1) CA2136835C (es)
DE (2) DE9307115U1 (es)
DK (1) DK0642366T3 (es)
ES (1) ES2118234T3 (es)
FI (1) FI945589A (es)
NO (1) NO944528L (es)
WO (1) WO1993024165A1 (es)

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GB9326574D0 (en) * 1993-12-31 1994-03-02 King S College London Dry power inhalers
WO1996004032A1 (de) * 1994-08-04 1996-02-15 BUKOR, Ruth-Maria Auswechselbares mundstück für inhalatoren mit integrierter, verfestigter, ringförmiger wirkstofftablette
DE4429707C1 (de) * 1994-08-04 1996-02-01 Bernhard Dipl Ing Hugemann Inhalator mit integrierter, verfestigter, ringförmiger Wirkstofftablette
DE29501527U1 (de) * 1995-02-01 1995-03-30 Kern & Liebers Vorrichtung zur Erzeugung inhalierbarer Wirkstoffpartikel
PT921830E (pt) * 1996-04-25 2002-12-31 Astrazeneca Ab Inalador
DE19629944C2 (de) * 1996-07-24 2003-04-24 Gaplast Gmbh Pulverinhalator
GB9722285D0 (en) * 1997-10-23 1997-12-17 Rhone Poulenc Rorer Ltd Inhalation device
ATE281860T1 (de) 1997-12-23 2004-11-15 Euro Celtique Sa Teilchenabscheider für einen inhalator
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
FI990915A0 (fi) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj Jauheinhalaattori
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
ES2235891T3 (es) 1999-05-27 2005-07-16 Euro-Celtique S.A. Uso de antisepticos en la fabricacion de una preparacion farmaceutica para la prevencion y tratamiento de infecciones y/o reestructuracion funcional del tejido en el interior del cuerpo humano.
IL146132A0 (en) 1999-05-27 2002-07-25 Euro Celtique Sa Preparations for the application of anti-infective and/or anti-inflammatory agents to external or internal parts of the human or animal body in functional and cosmetic tissue remodelling and repair treatments
US7297344B1 (en) 1999-05-27 2007-11-20 Euro-Celtique, S.A. Preparations for the promotion of wound healing in the upper respiratory tract and/or ear
DE19945155A1 (de) * 1999-09-21 2001-06-28 Medsym Aerzteservice Informati Verfahren zur Herstellung eines Medikaments
CA2401288A1 (en) 2000-02-28 2001-09-07 Vectura Limited Improvements in or relating to the delivery of oral drugs
AU2001263098A1 (en) 2000-05-12 2001-11-26 Iep Pharmaceutical Devices, Inc. Powder/liquid metering valve
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10350555A1 (de) * 2003-10-29 2005-06-09 Hugo Kern Und Liebers Gmbh & Co. Platinen- Und Federnfabrik Inhalator
DE102005001170A1 (de) 2005-01-10 2006-07-20 Pulmotec Gmbh Medizinisches Gerät
RS55114B1 (sr) 2005-05-18 2016-12-30 Raptor Pharmaceuticals Inc Aerosolizovani fluorohinoloni i njihove upotrebe
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
DE102007056263A1 (de) * 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz
DE102007058112A1 (de) 2007-12-03 2009-06-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Wirkstofftablette
ES2809177T3 (es) 2008-10-07 2021-03-03 Horizon Orphan Llc Inhalación de levofloxacino para reducir la inflamación pulmonar
AU2009302478B2 (en) 2008-10-07 2015-09-03 Horizon Orphan Llc Aerosol fluoroquinolone formulations for improved pharmacokinetics
CA2938650C (en) 2009-09-04 2018-01-09 Raptor Pharmaceuticals Inc. Use of aerosolized levofloxacin for treating cystic fibrosis
AU2010319328A1 (en) 2009-11-12 2012-05-31 Stc.Unm Dry powder inhaler with flutter dispersion member
WO2012078804A1 (en) 2010-12-07 2012-06-14 Respira Therapeutics, Inc. Dry powder inhaler
EP2670242B1 (en) 2011-01-31 2022-03-16 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
CA3172586A1 (en) 2013-07-31 2015-02-05 Avalyn Pharma Inc. Aerosol imatininb compounds and uses thereof
NZ760541A (en) 2014-01-10 2022-08-26 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
WO2016049463A1 (en) * 2014-09-25 2016-03-31 Altria Client Services Llc. Electronic inhalation device including an abrasive element
WO2016115379A1 (en) 2015-01-14 2016-07-21 Respira Therapeutics, Inc. Powder dispersion methods and devices
US10518070B1 (en) 2019-03-21 2019-12-31 King Saud University Device for powdering a solid unit dosage form of medication and administering the powder form
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof

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GB671582A (en) * 1949-04-16 1952-05-07 Donald Herbert Brooks Improvements in dispensers for medicinal and other powders
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US3027897A (en) * 1959-07-23 1962-04-03 Carofiglio Louis Edward Nasal inhaler
US3362405A (en) * 1964-04-06 1968-01-09 Hamilton O. Hazel Method and apparatus for admixing gas with solid particles
US3980074A (en) * 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
IT1017153B (it) * 1974-07-15 1977-07-20 Isf Spa Apparecchio per inalazioni
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
DE3274065D1 (de) * 1981-07-08 1986-12-11 Draco Ab Powder inhalator
GR861995B (en) * 1985-07-30 1986-11-04 Glaxo Group Ltd Devices for administering medicaments to patients
AT384552B (de) * 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
ATE111364T1 (de) * 1989-05-31 1994-09-15 Fisons Plc Medikament und inhalationsvorrichtung dafür.
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
DE4027390C2 (de) * 1990-08-30 1994-11-03 Boehringer Ingelheim Kg Treibgasfreies Inhalationsgerät
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments

Also Published As

Publication number Publication date
NO944528D0 (no) 1994-11-25
AU4066593A (en) 1993-12-30
CA2136835A1 (en) 1993-12-09
EP0642366B1 (de) 1997-10-08
AU686560B2 (en) 1998-02-12
DE9307115U1 (de) 1993-09-02
ATE158951T1 (de) 1997-10-15
FI945589A0 (fi) 1994-11-28
WO1993024165A1 (de) 1993-12-09
DE59307510D1 (de) 1997-11-13
US5673685A (en) 1997-10-07
FI945589A (fi) 1994-11-28
DK0642366T3 (da) 1998-07-20
CA2136835C (en) 2000-02-29
EP0642366A1 (de) 1995-03-15
NO944528L (no) 1994-11-25

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