ES2116652T3 - Hidrogenacion asimetrica de derivados de la cetoisoforona. - Google Patents

Hidrogenacion asimetrica de derivados de la cetoisoforona.

Info

Publication number
ES2116652T3
ES2116652T3 ES95109592T ES95109592T ES2116652T3 ES 2116652 T3 ES2116652 T3 ES 2116652T3 ES 95109592 T ES95109592 T ES 95109592T ES 95109592 T ES95109592 T ES 95109592T ES 2116652 T3 ES2116652 T3 ES 2116652T3
Authority
ES
Spain
Prior art keywords
cetoisoforona
derivatives
bencil
sup
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95109592T
Other languages
English (en)
Inventor
Emil Albin Broger
Yvo Crameri
Rudolf Schmid
Theodor Siegfried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2116652T3 publication Critical patent/ES2116652T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/283—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/06—Preparation of esters of carbonic or haloformic acids from organic carbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCESO PARA LA ELABORACION DE COMPUESTOS ACTIVOS OPTICOS DE LA FORMULA GENERAL DONDE R SIGNIFICA ALQUILO INFERIOR, ALCOXI INFERIOR, BENCILO O NR{SUP,1 SUB,2} , R{SUP,1} SIGNIFICA ALQUILO INFERIOR, FENILO, BENCILO O HIDROGENO Y * SIGNIFICA UN CENTRO ACTIVO OPTICO, CARACTERIZANDOSE DE TAL MODO QUE SE HIDROGENA DE FORMA ASIMETRICA DE DERIVADO ENOL DE CETOISOFORONA DE LA FORMULA GENERAL, DONDE R TIENE EL SIGNIFICADO ANTES DADO, EN PRESENCIA DE UN COMPLEJO DE RODIO DE UN ENLACE DIFOSFINA ACTIVO OPTICO.
ES95109592T 1994-07-07 1995-06-21 Hidrogenacion asimetrica de derivados de la cetoisoforona. Expired - Lifetime ES2116652T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH217394 1994-07-07

Publications (1)

Publication Number Publication Date
ES2116652T3 true ES2116652T3 (es) 1998-07-16

Family

ID=4227601

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95109592T Expired - Lifetime ES2116652T3 (es) 1994-07-07 1995-06-21 Hidrogenacion asimetrica de derivados de la cetoisoforona.

Country Status (9)

Country Link
US (1) US5543559A (es)
EP (1) EP0691325B1 (es)
JP (1) JP3710846B2 (es)
KR (1) KR100377712B1 (es)
CN (1) CN1061970C (es)
AT (1) ATE165080T1 (es)
DE (1) DE59501886D1 (es)
DK (1) DK0691325T3 (es)
ES (1) ES2116652T3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187961B1 (en) * 1997-11-06 2001-02-13 Roche Vitamins Inc. Process for the preparation of trans-(R,R)-actinol
US6849483B2 (en) * 2002-12-09 2005-02-01 Progressant Technologies, Inc. Charge trapping device and method of forming the same
US20060155150A1 (en) * 2004-10-01 2006-07-13 Lockwood Samuel F Methods for the synthesis of lutein
CN102180793B (zh) * 2011-03-15 2014-08-27 浙江新和成药业有限公司 一种2,3,5-三甲基氢醌二酯的合成方法
KR20160117841A (ko) 2015-03-31 2016-10-11 주식회사 이지이앤엠 일체형 산화 및 흡수에 의한 탈취장치
KR101653544B1 (ko) 2016-02-17 2016-09-02 이노엔비텍(주) 오염공기 탈취장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3000445C2 (de) 1980-01-08 1982-12-02 Degussa Ag, 6000 Frankfurt Rhodiumkomplexe und deren Verwendung
EP0251164B1 (en) 1986-06-25 1992-12-16 Kazuo Achiwa New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds
US5171892A (en) 1991-07-02 1992-12-15 E. I. Du Pont De Nemours And Company Chiral phospholanes via chiral 1,4-diol cyclic sulfates
SG42936A1 (en) 1992-04-02 1997-10-17 Ciba Geigy Ag Ferrocenyl diphosphines as ligands for homogeneous catalysts
US5374727A (en) 1992-06-19 1994-12-20 Hoffmann-La Roche Inc. Asymmetric hydrogenation of dihydro-pyrido [1,2-a]indoles

Also Published As

Publication number Publication date
DK0691325T3 (da) 1999-01-25
EP0691325A1 (de) 1996-01-10
EP0691325B1 (de) 1998-04-15
DE59501886D1 (de) 1998-05-20
CN1061970C (zh) 2001-02-14
KR960004313A (ko) 1996-02-23
JP3710846B2 (ja) 2005-10-26
ATE165080T1 (de) 1998-05-15
CN1127741A (zh) 1996-07-31
KR100377712B1 (ko) 2003-09-13
US5543559A (en) 1996-08-06
JPH0859554A (ja) 1996-03-05

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