ES2115854T3 - Esteres de 21-hidroxipregnano-acido quinolin-carboxilico y composiciones antibacterianas y antiinflamatorias que los contienen. - Google Patents
Esteres de 21-hidroxipregnano-acido quinolin-carboxilico y composiciones antibacterianas y antiinflamatorias que los contienen.Info
- Publication number
- ES2115854T3 ES2115854T3 ES94120195T ES94120195T ES2115854T3 ES 2115854 T3 ES2115854 T3 ES 2115854T3 ES 94120195 T ES94120195 T ES 94120195T ES 94120195 T ES94120195 T ES 94120195T ES 2115854 T3 ES2115854 T3 ES 2115854T3
- Authority
- ES
- Spain
- Prior art keywords
- hydroxypregnano
- quinolin
- antibacterial
- acid esters
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
ESTA INVENCION PROVEE UN NUEVO DERIVADO ESTEROIDE QUE TIENE LA ESTRUCTURA DE UN ESTER ENTRE EL GRUPO CARBOXILO DE UN ACIDO QUINOLONACARBOXILICO Y EL GRUPO HIDROXILO ALCOHOLICO EN LA POSICION 21 DE UN COMPONENTE ESTEROIDE, QUE TIENE LA SIGUIENTE FORMULA (I) (EN DONDE R ES UN ATOMO DE HIDROGENO, UN GRUPO METILO O UN GRUPO HIDROXILO) O SU SAL ACEPTABLE FARMACOLOGICAMENTE. EL COMPONENTE DE ESTA INVENCION TIENE ALTA ACTIVIDAD ANTIBACTERIAL Y ACTIVIDAD ANTIINFLAMATORIA EN UNO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32440593 | 1993-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2115854T3 true ES2115854T3 (es) | 1998-07-01 |
Family
ID=18165437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94120195T Expired - Lifetime ES2115854T3 (es) | 1993-12-22 | 1994-12-20 | Esteres de 21-hidroxipregnano-acido quinolin-carboxilico y composiciones antibacterianas y antiinflamatorias que los contienen. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5599807A (es) |
EP (1) | EP0659763B1 (es) |
KR (1) | KR950018036A (es) |
AT (1) | ATE166358T1 (es) |
CA (1) | CA2136803A1 (es) |
DE (1) | DE69410419T2 (es) |
ES (1) | ES2115854T3 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69817565T2 (de) * | 1997-02-11 | 2004-06-24 | The Victoria University Of Manchester | Bioreduktive konjugate zur gezielten wirkstoffzufuhr |
US6372712B1 (en) | 1998-05-22 | 2002-04-16 | The Board Of Trustees Of The Leland Stanford Jr. University | Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand |
US6696592B2 (en) | 2001-05-22 | 2004-02-24 | Nicox-S.A. | Methods of making 21-[4′-(nitrooxyalkyl)benzoate] corticosteroid derivatives and intermediates useful in the synthesis thereof |
GB0114672D0 (en) | 2001-06-15 | 2001-08-08 | Orthogenics As | Pharmaceutical formulations and methods of medical treatment |
AU2003265576A1 (en) * | 2002-08-23 | 2004-03-11 | The Mclean Hospital Corporation | Corticosteroid conjugates and uses thereof |
CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
EP1945240B1 (en) | 2005-09-16 | 2016-12-28 | Raptor Pharmaceutical Inc | Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof |
PT2398500T (pt) | 2009-02-20 | 2019-06-14 | 2 Bbb Medicines B V | Sistema de entrega de medicamentos à base de glutationas |
CN110075069A (zh) | 2009-05-06 | 2019-08-02 | 实验室护肤股份有限公司 | 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用 |
CU20110244A7 (es) | 2011-12-27 | 2013-08-29 | Ct De Investigación Y Desarrollo De Medicamentos Cidem | Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios |
AU2014225743A1 (en) | 2013-03-08 | 2015-09-24 | Allergan, Inc. | Antibiotic conjugates directly linked with steroid drugs |
WO2014138359A1 (en) | 2013-03-08 | 2014-09-12 | Allergan, Inc. | Steroid antibiotic conjugates |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH421957A (de) * | 1962-03-23 | 1966-10-15 | Thomae Gmbh Dr K | Verfahren zur Herstellung von Steroidestern |
JPS4925279A (es) * | 1972-06-29 | 1974-03-06 | ||
IT1036870B (it) * | 1975-02-13 | 1979-10-30 | Acraf | Derivati steroidei dell acido bendazolico |
GB1565680A (en) * | 1976-12-31 | 1980-04-23 | Leo Ab | Method for the preparation of carboxylic acid esters |
US5380839A (en) * | 1985-09-12 | 1995-01-10 | The Upjohn Company | Phenylpiperazinyl steroids |
AU4201189A (en) * | 1988-08-26 | 1990-03-23 | Alcon Laboratories, Inc. | Combination of quinolone antibiotics and steroids for topical ophthalmic use |
-
1994
- 1994-11-28 CA CA002136803A patent/CA2136803A1/en not_active Abandoned
- 1994-12-16 US US08/356,962 patent/US5599807A/en not_active Expired - Fee Related
- 1994-12-20 EP EP94120195A patent/EP0659763B1/en not_active Expired - Lifetime
- 1994-12-20 DE DE69410419T patent/DE69410419T2/de not_active Expired - Fee Related
- 1994-12-20 ES ES94120195T patent/ES2115854T3/es not_active Expired - Lifetime
- 1994-12-20 AT AT94120195T patent/ATE166358T1/de not_active IP Right Cessation
- 1994-12-21 KR KR1019940035684A patent/KR950018036A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE166358T1 (de) | 1998-06-15 |
KR950018036A (ko) | 1995-07-22 |
DE69410419T2 (de) | 1998-09-17 |
EP0659763A3 (en) | 1995-12-20 |
DE69410419D1 (de) | 1998-06-25 |
CA2136803A1 (en) | 1995-06-23 |
EP0659763A2 (en) | 1995-06-28 |
US5599807A (en) | 1997-02-04 |
EP0659763B1 (en) | 1998-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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