ES2112238T1 - Acido nucleico. - Google Patents

Acido nucleico.

Info

Publication number
ES2112238T1
ES2112238T1 ES97904008T ES97904008T ES2112238T1 ES 2112238 T1 ES2112238 T1 ES 2112238T1 ES 97904008 T ES97904008 T ES 97904008T ES 97904008 T ES97904008 T ES 97904008T ES 2112238 T1 ES2112238 T1 ES 2112238T1
Authority
ES
Spain
Prior art keywords
galanine
receiver
nucleic
mammal
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES97904008T
Other languages
English (en)
Inventor
Kelli E Smith
Christophe P G Gerald
Richard L Weinshank
David Linemeyer
Theresa Branchek
Carlos Forray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synaptic Pharmaceutical Corp
Original Assignee
Synaptic Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/626,685 external-priority patent/US5972624A/en
Application filed by Synaptic Pharmaceutical Corp filed Critical Synaptic Pharmaceutical Corp
Publication of ES2112238T1 publication Critical patent/ES2112238T1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)

Abstract

ESTA INVENCION DESCRIBE ACIDOS NUCLEICOS AISLADOS QUE CODIFICAN PARA RECEPTORES DE GALANINA DE MAMIFEROS, PROTEINAS DEL RECEPTOR DE GALANINA AISLADAS, VECTORES QUE INCLUYEN UN ACIDO NUCLEICO AISLADO QUE CODIFICA PARA UN RECEPTOR DE GALANINA DE MAMIFEROS, CELULAS QUE INCLUYEN DICHOS VECTORES, ANTICUERPOS DIRIGIDOS CONTRA UN RECEPTOR DE GALANINA DE MAMIFEROS, SONDAS DE ACIDO NUCLEICO UTILES PARA DETECTAR UN ACIDO NUCLEICO QUE CODIFICA PARA UN RECEPTOR DE GALANINA DE MAMIFERO, OLIGONUCLEOTIDOS ANTISENTIDO COMPLEMENTARIOS CON LAS SECUENCIAS EXCLUSIVAS DEL ACIDO NUCLEICO QUE CODIFICA PARA UN RECEPTOR DE GALANINA DE MAMIFERO, ANIMALES TRANSGENICOS NO HUMANOS QUE EXPRESAN EL ADN QUE CODIFICA PARA UN RECEPTOR DE GALANINA DE MAMIFERO NORMAL O MUTANTE, ASI COMO PROCEDIMIENTOS PARA DETERMINAR LA UNION DE COMPUESTOS A LOS RECEPTORES DE GALANINA DE MAMIFERO.
ES97904008T 1996-01-24 1997-01-24 Acido nucleico. Pending ES2112238T1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59049496A 1996-01-24 1996-01-24
US62604696A 1996-04-01 1996-04-01
US08/626,685 US5972624A (en) 1996-01-24 1996-04-01 Method of identifying ligands which bind recombinant galanin receptor (GALR2)
US72183796A 1996-09-27 1996-09-27

Publications (1)

Publication Number Publication Date
ES2112238T1 true ES2112238T1 (es) 1998-04-01

Family

ID=27505000

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97904008T Pending ES2112238T1 (es) 1996-01-24 1997-01-24 Acido nucleico.

Country Status (9)

Country Link
US (4) US6790656B1 (es)
EP (1) EP0819167A4 (es)
JP (1) JP2000504107A (es)
AU (1) AU730137B2 (es)
CA (1) CA2216227A1 (es)
DE (1) DE819167T1 (es)
ES (1) ES2112238T1 (es)
GR (1) GR980300016T1 (es)
WO (1) WO1997026853A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000504107A (ja) 1996-01-24 2000-04-04 シナプティック・ファーマスーティカル・コーポレーション ガラニンｇａｌｒ２受容体をコードするｄｎａおよびその使用
US6410686B1 (en) 1996-06-05 2002-06-25 Bayer Corporation Galanin receptor 2 protein
SE9602822D0 (sv) 1996-07-19 1996-07-19 Astra Pharma Inc New receptor
DK0918455T3 (da) * 1996-07-24 2003-08-04 Neurotargets Ltd Anvendelse af galanin til reparation af nerveskader
WO1998029441A1 (en) 1996-12-27 1998-07-09 Merck & Co., Inc. Human galanin receptor galr2 and nucleotides encoding same
WO1999031130A1 (en) 1997-12-17 1999-06-24 Merck & Co., Inc. Galanin receptor galr3 and nucleotides encoding same
US6337206B1 (en) 1997-12-18 2002-01-08 Merck & Co., Inc. Nucleic acid encoding mouse galanin receptor (GALR2)
US6232066B1 (en) * 1997-12-19 2001-05-15 Neogen, Inc. High throughput assay system
US20080132445A1 (en) * 2002-09-25 2008-06-05 Garvan Institute Of Medical Reserach Method for Inducing Mammary Epithelial Cell Differentiation
GB0403509D0 (en) * 2004-02-17 2004-03-24 Neuro Targets Ltd Galanin receptors and brain injury
US7309589B2 (en) * 2004-08-20 2007-12-18 Vironix Llc Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing
JP2008528951A (ja) * 2005-01-03 2008-07-31 ザ スクリプス リサーチ インスティテュート 抗うつ薬の標的
US20100210561A1 (en) * 2007-09-11 2010-08-19 Dorian Bevec Use of peptide as a therapeutic agent
AU2008361604A1 (en) * 2008-09-09 2010-03-18 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
AU2009301457B2 (en) * 2008-10-09 2015-08-13 Merck Patent Gmbh Estrogen and anti-estrogen marker genes
CN113512592A (zh) * 2021-04-23 2021-10-19 中国科学院深圳先进技术研究院 用于检测甘丙肽分泌细胞的引物、探针以及试剂盒
WO2024116101A1 (en) * 2022-11-29 2024-06-06 Neuracle Science Co., Ltd. Use of galr2 agonists to treat gastrointestinal and/or endocrine disorders

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436455A (en) * 1990-06-27 1995-07-25 Futrex Inc. Non-invasive near-infrared quantitative measurement instrument
US5462856A (en) 1990-07-19 1995-10-31 Bunsen Rush Laboratories, Inc. Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
JPH06510363A (ja) 1990-10-29 1994-11-17 ディカルブ　プラント　ジェネティクス 磁気性粒子を使用する生物学的材料の単離
AU1350792A (en) 1991-01-16 1992-08-27 General Hospital Corporation, The Human galanin
WO1992015015A1 (en) 1991-02-25 1992-09-03 Zymogenetic, Inc. Methods for detecting galanin antagonists
CA2105572A1 (en) 1991-03-06 1992-09-07 Helen F. Evans Human galanin, cdna clones encoding human galanin and a method of producing human galanin
SE9101472D0 (sv) 1991-05-15 1991-05-15 Trion Forskning & Utveckling Galanin antagonist
US5576296A (en) 1991-05-15 1996-11-19 Aktiebolaget Astra Galanin antagonist
US5436155A (en) 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
US5290808A (en) * 1992-11-06 1994-03-01 Carter-Wallace, Inc. Method to control the intake of food
FR2716205B1 (fr) * 1994-02-17 1996-04-12 Rhone Poulenc Rorer Sa Récepteur galanine, acides nucléiques, cellules transformées et utilisations.
US6399325B1 (en) 1994-10-13 2002-06-04 Takeda Chemical Industries, Ltd. DNA encoding a galanin receptor
US6562862B1 (en) * 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
JP2000504107A (ja) 1996-01-24 2000-04-04 シナプティック・ファーマスーティカル・コーポレーション ガラニンｇａｌｒ２受容体をコードするｄｎａおよびその使用
US5972624A (en) * 1996-01-24 1999-10-26 Synaptic Pharmaceutical Corporation Method of identifying ligands which bind recombinant galanin receptor (GALR2)
US6410686B1 (en) 1996-06-05 2002-06-25 Bayer Corporation Galanin receptor 2 protein
SE9602822D0 (sv) 1996-07-19 1996-07-19 Astra Pharma Inc New receptor
DK0918455T3 (da) 1996-07-24 2003-08-04 Neurotargets Ltd Anvendelse af galanin til reparation af nerveskader
WO1998029441A1 (en) * 1996-12-27 1998-07-09 Merck & Co., Inc. Human galanin receptor galr2 and nucleotides encoding same

Also Published As

Publication number Publication date
US20030215823A1 (en) 2003-11-20
DE819167T1 (de) 1998-04-09
GR980300016T1 (en) 1998-03-31
US6586191B2 (en) 2003-07-01
US7132248B2 (en) 2006-11-07
US20030082672A1 (en) 2003-05-01
EP0819167A4 (en) 2002-06-12
US20030129702A1 (en) 2003-07-10
WO1997026853A2 (en) 1997-07-31
WO1997026853A3 (en) 1997-10-23
US7060449B2 (en) 2006-06-13
JP2000504107A (ja) 2000-04-04
EP0819167A2 (en) 1998-01-21
AU730137B2 (en) 2001-03-01
AU1842797A (en) 1997-08-20
US6790656B1 (en) 2004-09-14
CA2216227A1 (en) 1997-07-31

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