GR980300016T1 - Dna encoding galanin galr2 receptors and uses thereof - Google Patents
Dna encoding galanin galr2 receptors and uses thereofInfo
- Publication number
- GR980300016T1 GR980300016T1 GR980300016T GR980300016T GR980300016T1 GR 980300016 T1 GR980300016 T1 GR 980300016T1 GR 980300016 T GR980300016 T GR 980300016T GR 980300016 T GR980300016 T GR 980300016T GR 980300016 T1 GR980300016 T1 GR 980300016T1
- Authority
- GR
- Greece
- Prior art keywords
- dna encoding
- galr2 receptors
- encoding galanin
- galanin galr2
- receptors
- Prior art date
Links
- 102000019432 Galanin Human genes 0.000 title 1
- 101800002068 Galanin Proteins 0.000 title 1
- SLZIZIJTGAYEKK-CIJSCKBQSA-N molport-023-220-247 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)CN)[C@@H](C)O)C1=CNC=N1 SLZIZIJTGAYEKK-CIJSCKBQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59049496A | 1996-01-24 | 1996-01-24 | |
US62604696A | 1996-04-01 | 1996-04-01 | |
US08/626,685 US5972624A (en) | 1996-01-24 | 1996-04-01 | Method of identifying ligands which bind recombinant galanin receptor (GALR2) |
US72183796A | 1996-09-27 | 1996-09-27 | |
PCT/US1997/001301 WO1997026853A2 (en) | 1996-01-24 | 1997-01-24 | Dna encoding galanin galr2 receptors and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GR980300016T1 true GR980300016T1 (en) | 1998-03-31 |
Family
ID=27505000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980300016T GR980300016T1 (en) | 1996-01-24 | 1998-03-31 | Dna encoding galanin galr2 receptors and uses thereof |
Country Status (9)
Country | Link |
---|---|
US (4) | US6790656B1 (el) |
EP (1) | EP0819167A4 (el) |
JP (1) | JP2000504107A (el) |
AU (1) | AU730137B2 (el) |
CA (1) | CA2216227A1 (el) |
DE (1) | DE819167T1 (el) |
ES (1) | ES2112238T1 (el) |
GR (1) | GR980300016T1 (el) |
WO (1) | WO1997026853A2 (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU730137B2 (en) | 1996-01-24 | 2001-03-01 | H. Lundbeck A/S | DNA encoding galanin GALR2 receptors and uses thereof |
US6410686B1 (en) | 1996-06-05 | 2002-06-25 | Bayer Corporation | Galanin receptor 2 protein |
SE9602822D0 (sv) | 1996-07-19 | 1996-07-19 | Astra Pharma Inc | New receptor |
JP2000516212A (ja) * | 1996-07-24 | 2000-12-05 | ユニバーシティー オブ ブリストル | ガラニン |
CA2275465A1 (en) * | 1996-12-27 | 1998-07-09 | Merck & Co., Inc. | Galanin receptor galr2 and nucleotides encoding same |
CA2326694A1 (en) | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Galanin receptor galr3 and nucleotides encoding same |
US6337206B1 (en) | 1997-12-18 | 2002-01-08 | Merck & Co., Inc. | Nucleic acid encoding mouse galanin receptor (GALR2) |
US6232066B1 (en) * | 1997-12-19 | 2001-05-15 | Neogen, Inc. | High throughput assay system |
US20080132445A1 (en) * | 2002-09-25 | 2008-06-05 | Garvan Institute Of Medical Reserach | Method for Inducing Mammary Epithelial Cell Differentiation |
GB0403509D0 (en) * | 2004-02-17 | 2004-03-24 | Neuro Targets Ltd | Galanin receptors and brain injury |
US7309589B2 (en) * | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
US20060177853A1 (en) * | 2005-01-03 | 2006-08-10 | The Scripps Research Institute | Antidepressant drug target |
CA2698690A1 (en) * | 2007-09-11 | 2009-04-09 | Mondobiotech Laboratories Ag | Thyrotropin releasing hormone for therapeutic applications |
KR20110056452A (ko) * | 2008-09-09 | 2011-05-30 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 펩티드의 용도 |
AU2009301457B2 (en) * | 2008-10-09 | 2015-08-13 | Merck Patent Gmbh | Estrogen and anti-estrogen marker genes |
CN113512592A (zh) * | 2021-04-23 | 2021-10-19 | 中国科学院深圳先进技术研究院 | 用于检测甘丙肽分泌细胞的引物、探针以及试剂盒 |
WO2024116101A1 (en) * | 2022-11-29 | 2024-06-06 | Neuracle Science Co., Ltd. | Use of galr2 agonists to treat gastrointestinal and/or endocrine disorders |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5436455A (en) * | 1990-06-27 | 1995-07-25 | Futrex Inc. | Non-invasive near-infrared quantitative measurement instrument |
US5462856A (en) | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
US5401629A (en) * | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
WO1992008133A1 (en) | 1990-10-29 | 1992-05-14 | Dekalb Plant Genetics | Isolation of biological materials using magnetic particles |
AU1350792A (en) | 1991-01-16 | 1992-08-27 | General Hospital Corporation, The | Human galanin |
WO1992015015A1 (en) * | 1991-02-25 | 1992-09-03 | Zymogenetic, Inc. | Methods for detecting galanin antagonists |
WO1992015681A1 (en) | 1991-03-06 | 1992-09-17 | Garvan Institute Of Medical Research | HUMAN GALANIN, cDNA CLONES ENCODING HUMAN GALANIN AND A METHOD OF PRODUCING HUMAN GALANIN |
US5576296A (en) * | 1991-05-15 | 1996-11-19 | Aktiebolaget Astra | Galanin antagonist |
SE9101472D0 (sv) | 1991-05-15 | 1991-05-15 | Trion Forskning & Utveckling | Galanin antagonist |
US5436155A (en) * | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
US5290808A (en) | 1992-11-06 | 1994-03-01 | Carter-Wallace, Inc. | Method to control the intake of food |
FR2716205B1 (fr) | 1994-02-17 | 1996-04-12 | Rhone Poulenc Rorer Sa | Récepteur galanine, acides nucléiques, cellules transformées et utilisations. |
EP0711830A3 (en) | 1994-10-13 | 1997-06-11 | Takeda Chemical Industries Ltd | Murine and human galanin receptor |
US6562862B1 (en) | 1994-10-20 | 2003-05-13 | Eli Lilly And Company | Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y |
US5972624A (en) * | 1996-01-24 | 1999-10-26 | Synaptic Pharmaceutical Corporation | Method of identifying ligands which bind recombinant galanin receptor (GALR2) |
AU730137B2 (en) | 1996-01-24 | 2001-03-01 | H. Lundbeck A/S | DNA encoding galanin GALR2 receptors and uses thereof |
US6410686B1 (en) | 1996-06-05 | 2002-06-25 | Bayer Corporation | Galanin receptor 2 protein |
SE9602822D0 (sv) | 1996-07-19 | 1996-07-19 | Astra Pharma Inc | New receptor |
JP2000516212A (ja) | 1996-07-24 | 2000-12-05 | ユニバーシティー オブ ブリストル | ガラニン |
CA2275465A1 (en) * | 1996-12-27 | 1998-07-09 | Merck & Co., Inc. | Galanin receptor galr2 and nucleotides encoding same |
-
1997
- 1997-01-24 AU AU18427/97A patent/AU730137B2/en not_active Ceased
- 1997-01-24 WO PCT/US1997/001301 patent/WO1997026853A2/en not_active Application Discontinuation
- 1997-01-24 EP EP97904008A patent/EP0819167A4/en not_active Withdrawn
- 1997-01-24 ES ES97904008T patent/ES2112238T1/es active Pending
- 1997-01-24 CA CA002216227A patent/CA2216227A1/en not_active Abandoned
- 1997-01-24 JP JP9527082A patent/JP2000504107A/ja not_active Withdrawn
- 1997-01-24 US US09/011,553 patent/US6790656B1/en not_active Expired - Fee Related
- 1997-01-24 DE DE0819167T patent/DE819167T1/de active Pending
- 1997-07-23 US US08/899,112 patent/US6586191B2/en not_active Expired - Fee Related
-
1998
- 1998-03-31 GR GR980300016T patent/GR980300016T1/el unknown
-
2002
- 2002-10-31 US US10/285,019 patent/US7132248B2/en not_active Expired - Fee Related
- 2002-11-18 US US10/298,992 patent/US7060449B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU730137B2 (en) | 2001-03-01 |
EP0819167A2 (en) | 1998-01-21 |
US20030215823A1 (en) | 2003-11-20 |
WO1997026853A3 (en) | 1997-10-23 |
CA2216227A1 (en) | 1997-07-31 |
JP2000504107A (ja) | 2000-04-04 |
US7132248B2 (en) | 2006-11-07 |
US6586191B2 (en) | 2003-07-01 |
US6790656B1 (en) | 2004-09-14 |
US7060449B2 (en) | 2006-06-13 |
EP0819167A4 (en) | 2002-06-12 |
WO1997026853A2 (en) | 1997-07-31 |
ES2112238T1 (es) | 1998-04-01 |
US20030129702A1 (en) | 2003-07-10 |
AU1842797A (en) | 1997-08-20 |
DE819167T1 (de) | 1998-04-09 |
US20030082672A1 (en) | 2003-05-01 |
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