ES2111002T3 - Factor activador de macrofagos derivado de la proteina de fijacion de vitamina d. - Google Patents
Factor activador de macrofagos derivado de la proteina de fijacion de vitamina d.Info
- Publication number
- ES2111002T3 ES2111002T3 ES91917591T ES91917591T ES2111002T3 ES 2111002 T3 ES2111002 T3 ES 2111002T3 ES 91917591 T ES91917591 T ES 91917591T ES 91917591 T ES91917591 T ES 91917591T ES 2111002 T3 ES2111002 T3 ES 2111002T3
- Authority
- ES
- Spain
- Prior art keywords
- macrophagus
- vitamin
- activating factor
- factor derived
- fixation protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003213 activating effect Effects 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 229940088594 vitamin Drugs 0.000 title abstract 2
- 229930003231 vitamin Natural products 0.000 title abstract 2
- 235000013343 vitamin Nutrition 0.000 title abstract 2
- 239000011782 vitamin Substances 0.000 title abstract 2
- 150000003722 vitamin derivatives Chemical class 0.000 title abstract 2
- 102000005744 Glycoside Hydrolases Human genes 0.000 abstract 1
- 108010031186 Glycoside Hydrolases Proteins 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SE PRESENTA UN NUEVO Y POTENTE FACTOR DE ACTIVACION DE MACROFAGOS QUE SE PREPARA IN VITRO TRATANDO UN COMPONENTE ESPECIFICO DEL GRUPO HUMANO, TAMBIEN CONOCIDO COMO PROTEINA DE UNION DE LA VITAMINA D HUMANA, CON GLICOSIDASAS. EL COMPONENTE ESPECIFICO DE GRUPO, QUE SE AISLA A PARTIR DE LA SANGRE OBTENIDA POR PROCEDIMIENTOS CONOCIDOS, SE CONVIERTE DE ESTA FORMA EN UN FACTOR ACTIVADOR DE MACROFAGOS ALTAMENTE POTENTES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/576,248 US5177002A (en) | 1989-11-20 | 1990-08-31 | In vitro enzymatic conversion of glycosylated human vitamin D binding protein to a potent macrophage activating factor |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2111002T3 true ES2111002T3 (es) | 1998-03-01 |
Family
ID=24303582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91917591T Expired - Lifetime ES2111002T3 (es) | 1990-08-31 | 1991-08-29 | Factor activador de macrofagos derivado de la proteina de fijacion de vitamina d. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5177002A (es) |
EP (1) | EP0546096B1 (es) |
JP (1) | JP2596491B2 (es) |
AT (1) | ATE161580T1 (es) |
AU (1) | AU8654191A (es) |
CA (1) | CA2092720C (es) |
DE (1) | DE69128535T2 (es) |
ES (1) | ES2111002T3 (es) |
WO (1) | WO1992004459A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177001A (en) * | 1989-11-20 | 1993-01-05 | Nobuto Yamamoto | In vitro enzymatic conversion of glycosylated mammalian vitamin D-binding protein to a potent macrophage activating factor |
US5326749A (en) * | 1989-11-20 | 1994-07-05 | Nobuto Yamamoto | Macrophage activating factor from vitamin D binding protein |
US5627029A (en) * | 1991-05-03 | 1997-05-06 | Genzyme Corporation | Method for obtaining informative cells |
US5691160A (en) * | 1992-08-14 | 1997-11-25 | Biogen, Inc. | Effects of actin filaments of fibrin clot structure and lysis |
US5641747A (en) * | 1994-07-25 | 1997-06-24 | Temple University-Of The Commonwealth System Of Higher Education | Treatment of osteopetrotic diseases |
US20060014143A1 (en) * | 1995-06-07 | 2006-01-19 | Nobuto Yamamoto | Preparation of potent macrophage activating factors derived from cloned vitamin D binding protein and its domain and their therapeutic usage for cancer, HIV-infection and osteopetrosis |
US6410269B1 (en) * | 1995-06-07 | 2002-06-25 | Nobuto Yamamoto | Preparation of potent macrophage activating factors derived from cloned vitamin D binding protein and its domain and their therapeutic usage for cancer, HIV-infection and osteopetrosis |
AU6137801A (en) * | 2000-05-09 | 2001-11-20 | Childrens Medical Center | Method and composition for the treatment of angiogenesis |
DE60226327T2 (de) * | 2001-08-14 | 2009-07-09 | Statens Serum Institut | Reinigungsverfahren zur grossmassstabigen produktion von gc-globulin, damit erhaltenes produkt und dessen verwendung in medizin |
EP2612921B1 (en) * | 2010-09-03 | 2016-11-02 | Morita Pharmaceutical Ind., Ltd. | Method for production of novel degalactosylated gc globulin |
CA2832487A1 (en) | 2011-04-07 | 2012-10-11 | Efranat Ltd. | Macrophage activating factor for pharmaceutical compositions |
ES2805795T3 (es) * | 2012-09-28 | 2021-02-15 | Ellis Kline | Régimen de glicosidasa para el tratamiento de enfermedades infecciosas |
CN105530950A (zh) * | 2013-06-09 | 2016-04-27 | 艾弗兰纳特有限公司 | 包含Gc-巨噬细胞活化因子的组合物及其用途 |
US20210198307A1 (en) * | 2017-12-15 | 2021-07-01 | Foundation For Biomedical Research And Innovation At Kobe | Method for producing active gcmaf |
-
1990
- 1990-08-31 US US07/576,248 patent/US5177002A/en not_active Expired - Lifetime
-
1991
- 1991-08-29 EP EP91917591A patent/EP0546096B1/en not_active Expired - Lifetime
- 1991-08-29 AT AT91917591T patent/ATE161580T1/de not_active IP Right Cessation
- 1991-08-29 WO PCT/US1991/006172 patent/WO1992004459A1/en active IP Right Grant
- 1991-08-29 ES ES91917591T patent/ES2111002T3/es not_active Expired - Lifetime
- 1991-08-29 JP JP3516260A patent/JP2596491B2/ja not_active Expired - Lifetime
- 1991-08-29 CA CA002092720A patent/CA2092720C/en not_active Expired - Lifetime
- 1991-08-29 DE DE69128535T patent/DE69128535T2/de not_active Expired - Lifetime
- 1991-08-29 AU AU86541/91A patent/AU8654191A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0546096A1 (en) | 1993-06-16 |
DE69128535T2 (de) | 1998-05-20 |
AU8654191A (en) | 1992-03-30 |
ATE161580T1 (de) | 1998-01-15 |
CA2092720A1 (en) | 1992-03-01 |
DE69128535D1 (de) | 1998-02-05 |
EP0546096B1 (en) | 1997-12-29 |
US5177002A (en) | 1993-01-05 |
WO1992004459A1 (en) | 1992-03-19 |
JP2596491B2 (ja) | 1997-04-02 |
JPH06503716A (ja) | 1994-04-28 |
EP0546096A4 (es) | 1994-04-27 |
CA2092720C (en) | 1999-12-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2111002T3 (es) | Factor activador de macrofagos derivado de la proteina de fijacion de vitamina d. | |
ES2120416T3 (es) | Inhibidores del crecimiento tumoral derivados de tejidos, metodos de preparacion y usos de dichos inhibidores. | |
TR200301846T2 (tr) | Cripto bloke edici Antikorlar ve bu antikorların kullanımları. | |
BG99605A (en) | Antagonists of the growth factor or endothelial cells of the circulatory system | |
MX162688A (es) | Suturas compuestas de seda y elastomeros termoplasticos hidrofobos | |
ATE368054T1 (de) | Verbindungen und methoden zur modulierung von occludin-abhängiger gewebepermeabilität | |
SG170730A1 (en) | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 | |
IL127558A0 (en) | Hepatocyte growth factor receptor agonists and uses thereof | |
DK0429570T3 (da) | Osteoinducerende præparater | |
NL300353I1 (nl) | Geneesmiddelen met monoclonale antilichamen, die specifiek zijn voor de menselijk epidermale groeifactorreceptor | |
DK275482A (da) | Medicinske klaebeark til behandling af hjertesygdomme samt fremgangsmaade til fremstilling deraf | |
HK1048831A1 (en) | Human ctla-4 antibodies and their uses | |
DE60020529D1 (de) | Antikörper zur krebsbehandlung und -diagnose | |
DK0396387T3 (da) | Nyt antistoffremføringssystem for modifikatorer for biologisk respons | |
CY1108765T1 (el) | ΑΓΩΓΗ ME ΑΝΤΙΣΩΜΑΤΑ ANTI-ErbB2 | |
BR9712259A (pt) | Colostrininin, uso do mesmo, processos de tratar distúrbios do sistema nervoso central e/ou do sistema imune, de preparar colostrinin de colostro de mamìferos e de produzir uma composição farmacêutica, composição farmacêutica, suplemento dietético, nanopeptìdeo, e, uso do mesmo. | |
NO883306D0 (no) | Farmasoeytisk aktive konjugater med forbedret bindingsspesifisitet for kroppsvev. | |
ATE97316T1 (de) | Kosmetisches mittel und zusammensetzung zur behandlung der haut. | |
NO971341L (no) | Promoter for reseptor tyrosinkinase TIE | |
ES2128348T3 (es) | Obtencion de composiciones para el tratamiento de alteraciones de la proliferacion celular. | |
ES2074983T3 (es) | Procedimieto para el aislamiento de proteinas de membranas basales a partir de tejidos humanos y animales. | |
DE3580524D1 (de) | Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen. | |
ATE222501T1 (de) | Tissue-faktor zur beeinflussung von gefässbildung | |
ATE274920T1 (de) | Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen | |
ATE101519T1 (de) | Verwendung von gestoden zur herstellung von arzneimitteln. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 546096 Country of ref document: ES |