ES2107280T3 - Sales de nefazodona que tienen velocidades de disolucion mejoradas. - Google Patents

Sales de nefazodona que tienen velocidades de disolucion mejoradas.

Info

Publication number
ES2107280T3
ES2107280T3 ES95307812T ES95307812T ES2107280T3 ES 2107280 T3 ES2107280 T3 ES 2107280T3 ES 95307812 T ES95307812 T ES 95307812T ES 95307812 T ES95307812 T ES 95307812T ES 2107280 T3 ES2107280 T3 ES 2107280T3
Authority
ES
Spain
Prior art keywords
salts
nefazodone
improved dissolution
dissolution
dissolution speeds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95307812T
Other languages
English (en)
Inventor
Hemant N Joshi
Terry D Wilson
Jatin M Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2107280T3 publication Critical patent/ES2107280T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

LAS SALES DE NEFAZODONA L-MALATA, L-TARTRATA Y METANO SULFONADAS MUESTRAN UNA DISOLUCION INTRINSECA AL AGUA Y UN REACTIVO COMPENSADOR THAM SIGNIFICATIVAMENTE MAS ALTO COMPARADO CON OTRAS SALES DE NEFAZODONA. LOS INDICES DE DISOLUCION MAS RAPIDOS DE ESTAS SALES A PH''S MAS ELEVADOS PUEDE SUGERIR MEJOR DISOLUCION Y ABSORCION EN EL INTESTINO, Y UNA BIODISPONIBILIDAD MEJORADA PARA FORMULACIONES ORALES.
ES95307812T 1994-11-02 1995-11-01 Sales de nefazodona que tienen velocidades de disolucion mejoradas. Expired - Lifetime ES2107280T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33339094A 1994-11-02 1994-11-02

Publications (1)

Publication Number Publication Date
ES2107280T3 true ES2107280T3 (es) 1997-11-16

Family

ID=23302579

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95307812T Expired - Lifetime ES2107280T3 (es) 1994-11-02 1995-11-01 Sales de nefazodona que tienen velocidades de disolucion mejoradas.

Country Status (10)

Country Link
US (1) US6034085A (es)
EP (1) EP0710653B1 (es)
JP (1) JPH08208480A (es)
AT (1) ATE157659T1 (es)
AU (1) AU689645B2 (es)
CA (1) CA2160423A1 (es)
DE (1) DE69500652T2 (es)
DK (1) DK0710653T3 (es)
ES (1) ES2107280T3 (es)
GR (1) GR3025376T3 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
PT1071425E (pt) * 1998-04-24 2007-11-16 Scarista Ltd ''tratamento da depressão e composições farmacêuticas para o efeito''
ES2152860B1 (es) * 1998-10-23 2001-08-16 Finaf 92 Sa Forma cristalina de la nefazodona y procedimiento para su preparacion.
WO2000025790A1 (en) * 1998-11-02 2000-05-11 Alza Corporation Controlled delivery of antidepressants
US20030129680A1 (en) * 2001-10-31 2003-07-10 O'connor Thomas Patrick Multi-analyte assay device
US7183060B2 (en) * 2005-02-22 2007-02-27 Idexx Laboratories, Inc. Peptides for detection of antibody to Ehrlichia ewingii
US7407770B2 (en) * 2001-01-18 2008-08-05 Idexx Corporation Compositions and methods for detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies
US7087372B2 (en) * 2001-01-18 2006-08-08 Idexx Laboratories, Inc. Compositions and methods for detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies
US20030194756A1 (en) 2002-04-12 2003-10-16 O'connor Thomas Patrick Peptides for detection of antibody to Ehrlichia equi
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
GB0217056D0 (en) * 2002-07-23 2002-08-28 Ass Octel Use
WO2005065317A2 (en) 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
AU2004311879B2 (en) * 2003-12-31 2010-08-05 Cima Labs Inc. Effervescent oral opiate dosage form
BRPI0418228B8 (pt) * 2003-12-31 2021-05-25 Cima Labs Inc forma de dosagem, e, método de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil
US20060069060A1 (en) * 2004-09-27 2006-03-30 Sanjeev Redkar Salts of decitabine
US20060063735A1 (en) * 2004-09-17 2006-03-23 Supergen, Inc. Salts of 5-azacytidine
US7507789B2 (en) * 2007-04-09 2009-03-24 Idexx Laboratories, Inc. Detection of Anaplasma platys
WO2009039414A2 (en) 2007-09-21 2009-03-26 Idexx Laboratories, Inc. Methods and compositions for detection of ehrlichia chaffeensis (vlpt)
CA2700474C (en) * 2007-09-21 2016-10-04 Idexx Laboratories, Inc. Methods and compositions for detection of ehrlichia chaffeensis (p120)
WO2009070507A2 (en) * 2007-11-27 2009-06-04 Idexx Laboratories, Inc. Anaplasma phagocytophilum (aph) antigens and antibodies specific for anaplasma
MX2011003634A (es) * 2008-10-08 2011-05-02 Idexx Lab Inc Composiciones y metodos para la deteccion de anticuerpos especificos de anaplasma phagocytophilum (aph) y anaplasma platys (apl).
US20120065221A1 (en) 2009-02-26 2012-03-15 Theraquest Biosciences, Inc. Extended Release Oral Pharmaceutical Compositions of 3-Hydroxy-N-Methylmorphinan and Method of Use
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
WO2013113000A2 (en) 2012-01-26 2013-08-01 Luc Montagnier Detection of dna sequences as risk factors for hiv infection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
IT1196429B (it) * 1986-07-01 1988-11-16 Mediolanum Farmaceutici Srl Processo per la preparazione di pirido benzotiazine ad attivita' antibatterica e loro sali con acidi solfonici
US5188836A (en) * 1990-07-27 1993-02-23 Warner-Lambert Company Sustained release formulations
TW279864B (es) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv

Also Published As

Publication number Publication date
DE69500652T2 (de) 1998-02-19
EP0710653B1 (en) 1997-09-03
DE69500652D1 (de) 1997-10-09
EP0710653A1 (en) 1996-05-08
US6034085A (en) 2000-03-07
JPH08208480A (ja) 1996-08-13
CA2160423A1 (en) 1996-05-03
AU3458395A (en) 1996-05-09
AU689645B2 (en) 1998-04-02
GR3025376T3 (en) 1998-02-27
DK0710653T3 (da) 1997-12-08
ATE157659T1 (de) 1997-09-15

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