ES2104476T3 - Ensayo para determinar el glaucoma de angulo abierto primario (gaap) por analisis de la actividad de la 3-alfa-hidroxiesteroide-deshidrogenasa de las celulas sanguineas perifericas y kit para realizar el citado ensayo. - Google Patents

Ensayo para determinar el glaucoma de angulo abierto primario (gaap) por analisis de la actividad de la 3-alfa-hidroxiesteroide-deshidrogenasa de las celulas sanguineas perifericas y kit para realizar el citado ensayo.

Info

Publication number
ES2104476T3
ES2104476T3 ES95905938T ES95905938T ES2104476T3 ES 2104476 T3 ES2104476 T3 ES 2104476T3 ES 95905938 T ES95905938 T ES 95905938T ES 95905938 T ES95905938 T ES 95905938T ES 2104476 T3 ES2104476 T3 ES 2104476T3
Authority
ES
Spain
Prior art keywords
test
open angle
angle glaucoma
primary open
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95905938T
Other languages
English (en)
Inventor
A Louis Southren
Bernard I Weinstein
Gary G Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Medical College
Original Assignee
New York Medical College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Medical College filed Critical New York Medical College
Application granted granted Critical
Publication of ES2104476T3 publication Critical patent/ES2104476T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

SE PRESENTA UNA PRUEBA PARA DETERMINAR LOS PACIENTES QUE O BIEN SUFREN DE GLAUCOMA DE ANGULO ABIERTO PRIMARIO O QUE TIENE EL RIESGO DE DESARROLLAR GLAUCOMA DE ANGULO ABIERTO PRIMARIO. LA PRUEBA COMPRENDE LA COMPROBACION DE CELULAS, PREFERIBLEMENTE CELULAS DE LINFOCITOS, BUSCANDO LA ACTIVIDAD DE LA 3 {AL}-HSD Y LA DETERMINACION A PARTIR DEL NIVEL DE LA ACTIVIDAD COMPROBADA DE CUANDO EL PACIENTE BIEN ESTA SUFRIENDO EL GLAUCOMA DE ANGULO ABIERTO PRIMARIO O PRESENTA EL RIESGO DE SUFRIR EL MISMO.
ES95905938T 1993-12-17 1994-12-14 Ensayo para determinar el glaucoma de angulo abierto primario (gaap) por analisis de la actividad de la 3-alfa-hidroxiesteroide-deshidrogenasa de las celulas sanguineas perifericas y kit para realizar el citado ensayo. Expired - Lifetime ES2104476T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/169,611 US5376534A (en) 1993-12-17 1993-12-17 Use of decreased 3-alpha-hydroxysteroid dehydrogenase activity in peripheral lymphocytes or other cells of patients with primary open angle glaucoma as a diagnostic indicator

Publications (1)

Publication Number Publication Date
ES2104476T3 true ES2104476T3 (es) 1997-10-01

Family

ID=22616414

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95905938T Expired - Lifetime ES2104476T3 (es) 1993-12-17 1994-12-14 Ensayo para determinar el glaucoma de angulo abierto primario (gaap) por analisis de la actividad de la 3-alfa-hidroxiesteroide-deshidrogenasa de las celulas sanguineas perifericas y kit para realizar el citado ensayo.

Country Status (10)

Country Link
US (1) US5376534A (es)
EP (1) EP0734455B1 (es)
JP (1) JPH09506515A (es)
AT (1) ATE152776T1 (es)
AU (1) AU1436195A (es)
CA (1) CA2175996A1 (es)
DE (1) DE69403093T2 (es)
ES (1) ES2104476T3 (es)
GR (1) GR3024195T3 (es)
WO (1) WO1995016790A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080058429A1 (en) * 2003-02-14 2008-03-06 A Louis Southren Diagnosis Of Primary Open Angle Glaucoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863912A (en) * 1986-05-19 1989-09-05 New York Medical College Use of tetrahydrocortisol in glaucoma therapy

Also Published As

Publication number Publication date
CA2175996A1 (en) 1995-06-22
DE69403093D1 (de) 1997-06-12
ATE152776T1 (de) 1997-05-15
WO1995016790A1 (en) 1995-06-22
EP0734455A1 (en) 1996-10-02
AU1436195A (en) 1995-07-03
GR3024195T3 (en) 1997-10-31
JPH09506515A (ja) 1997-06-30
DE69403093T2 (de) 1997-11-20
EP0734455B1 (en) 1997-05-07
US5376534A (en) 1994-12-27

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