ES2101712T3 - Procedimiento para la preparacion de treo-4-alcoxi-5-(arilhidroximetil)-2(5h)-furanonas. - Google Patents

Procedimiento para la preparacion de treo-4-alcoxi-5-(arilhidroximetil)-2(5h)-furanonas.

Info

Publication number
ES2101712T3
ES2101712T3 ES91121539T ES91121539T ES2101712T3 ES 2101712 T3 ES2101712 T3 ES 2101712T3 ES 91121539 T ES91121539 T ES 91121539T ES 91121539 T ES91121539 T ES 91121539T ES 2101712 T3 ES2101712 T3 ES 2101712T3
Authority
ES
Spain
Prior art keywords
furanonas
arilhidroximetil
alcoxi
treo
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91121539T
Other languages
English (en)
Inventor
David Dr Laffan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2101712T3 publication Critical patent/ES2101712T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

A TRAVES DE LA CONDENSACION DE 4-ALCOXI-2(5H)-FURANONES CON BENZ-ALDEHIDO EN PRESENCIA DE HIDROXIDO DE LITIO SE GANA TREO-4-ALCOXI -5-(ARILHIDROXIMETIL)-2(5H)-FURANONES SIN IMPUREZAS DE ERITRO-ESTEROISOMEROS CORRESPONDIENTES. LA CONDENSACION ES REALIZADA PREFERIBLEMENTE EN ACETONITRILO ACUOSO, Y EL PRODUCTO SE PRECIPITA DE LA MEZCLA DE REACCION POR MEDIO DE LA ADICCION DE AGUA. LOS PRODUCTOS FABRICABLES DEL PROCEDIMIENTO, SEGUN LA INVENCION, SON ACTIVADORES FARMACEUTICOS CONOCIDOS POR SU EFECTO ANTIEPILEPTICO O BIEN ANTICONVULSIVO.
ES91121539T 1990-12-20 1991-12-16 Procedimiento para la preparacion de treo-4-alcoxi-5-(arilhidroximetil)-2(5h)-furanonas. Expired - Lifetime ES2101712T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH405690 1990-12-20

Publications (1)

Publication Number Publication Date
ES2101712T3 true ES2101712T3 (es) 1997-07-16

Family

ID=4269000

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91121539T Expired - Lifetime ES2101712T3 (es) 1990-12-20 1991-12-16 Procedimiento para la preparacion de treo-4-alcoxi-5-(arilhidroximetil)-2(5h)-furanonas.

Country Status (9)

Country Link
US (1) US5200531A (es)
EP (1) EP0492347B1 (es)
JP (1) JP3047582B2 (es)
AT (1) ATE150016T1 (es)
CA (1) CA2058144C (es)
DE (1) DE59108615D1 (es)
DK (1) DK0492347T3 (es)
ES (1) ES2101712T3 (es)
NO (1) NO179706C (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2211503A1 (en) * 1996-09-04 1998-03-04 Josef Schroer Process for the preparation of tetronic acid derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3615157A1 (de) * 1986-05-05 1987-11-12 Schwabe Willmar Gmbh & Co 5-arylalkyl-4-alkoxy-2(5h)-furanone, zwischenprodukte und verfahren zu ihrer herstellung sowie ihre anwendung als therapeutische wirkstoffe

Also Published As

Publication number Publication date
JP3047582B2 (ja) 2000-05-29
NO915029L (no) 1992-06-22
CA2058144A1 (en) 1992-06-21
JPH04316569A (ja) 1992-11-06
ATE150016T1 (de) 1997-03-15
NO179706C (no) 1996-12-04
CA2058144C (en) 2002-08-20
EP0492347B1 (de) 1997-03-12
DE59108615D1 (de) 1997-04-17
NO179706B (no) 1996-08-26
US5200531A (en) 1993-04-06
DK0492347T3 (da) 1997-04-01
NO915029D0 (no) 1991-12-19
EP0492347A1 (de) 1992-07-01

Similar Documents

Publication Publication Date Title
MA26551A1 (fr) Agonistes de prostaglandines nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
YU48323B (sh) Postupak za dobijanje askorbinske kiseline
ES2003293A6 (es) Procedimiento de obtencion de 5-arilalquil-4-alcoxy-2(5h)-furanonas
MA24484A1 (fr) Atropisomeres de 3-aryl-4(3h)-quinazolinones, procede pour leur preparation et compositions les contenant .
EA200200479A1 (ru) Новые олигосахариды, их получение и содержащие их фармацевтические композиции
DE3667059D1 (en) Benzodipyrroles, processes for their preparation and pharmaceutical compositions containing these compounds
ES2101712T3 (es) Procedimiento para la preparacion de treo-4-alcoxi-5-(arilhidroximetil)-2(5h)-furanonas.
DE59006966D1 (de) Vefahren zur Herstellung von hochreinen Polymerisaten des Tetrahydrofurans.
MX9301747A (es) Microorganismos capaces de producir selectivamente los compuestos a y b de las estreptograminas, procedimiento para su preparacion y las estreptograminas producidas a partir del mismo.
EA199700271A1 (ru) Композиции, состоящие из тирозина и полимеризованного аллергена
TNSN90121A1 (fr) Nouvelles tetrahydro-imidazo 1,4 benzodiazepines antivirales et procede pour leur preparation.
EP0325967A3 (en) Process for the preparation of pure enantiomers of 2,2,4-trisubstituted 1,3-dioxolanes
JPS5238774A (en) Treatment of acidic or alkaline waste water containing miscellaneous s ubstances
ES2071723T3 (es) Bencilseleniobenzoamidas de aminopiridinas y picolilaminas.
RU94037751A (ru) Способ выделения карбоната натрия и сульфата калия из содо-поташных растворов переработки нефелинов
FR2404004A1 (fr) Nouveaux derives o- et s-glycosides de nouveaux lactols bicycliques, procede pour leur preparation et compositions pharmaceutiques les contenant
JPS5687510A (en) Preparation of germicide capable of causing coagulation of germicidal component by bringing pyrolignous acid formed from wood dry distilling and coal making oven into contact with kerosine by air
BR0111727A (pt) Compostos e composições antipicornavirais, seus usos farmacêuticos, e materiais para a sua sìntese
DE59005445D1 (de) Picolylselenobenzamide von Aminopyridinen, Anilinen und Picolylaminen.
EA200000632A1 (ru) Способ отделения загрязнений от 3-(2'-ацетоксиэтил)-дигидро-2(3н) фуранона
RU93048526A (ru) Вещество для инактивации вируса гриппа, способ его получения и способ его применения
TH45444A (th) (เมทิลซัลโฟนิล) ฟีนิล-2-(5h)-ฟูราโนน ที่เป็นตัวขัดขวาง cox-2
EA199800452A1 (ru) ДИГИДРАТ (2R,3S)-3-ТРЕТ-БУТОКСИКАРБОНИЛАМИНО-2-ГИДРОКСИ-3-ФЕНИЛПРОПИОНАТ 4,10β-ДИАЦЕТОКСИ-2α-БЕНЗОИЛОКСИ-5β, 20-ЭПОКСИ-1-ГИДРОКСИ-9-ОКСО-19-НОР-ЦИКЛОПРОПА[G]ТАКС-II-ЕН-13α-ИЛА И СПОСОБ ЕГО ПОЛУЧЕНИЯ
MX6526A (es) Procedimiento para la preparacion de aminoacido insaturados, producto obtenido y composicion farmaceutica util como anticonvulsivo.
DK544789A (da) Transkaryot implantering

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 492347

Country of ref document: ES