ES2099007A1 - Derivados de indol. - Google Patents
Derivados de indol.Info
- Publication number
- ES2099007A1 ES2099007A1 ES09301604A ES9301604A ES2099007A1 ES 2099007 A1 ES2099007 A1 ES 2099007A1 ES 09301604 A ES09301604 A ES 09301604A ES 9301604 A ES9301604 A ES 9301604A ES 2099007 A1 ES2099007 A1 ES 2099007A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- alkinylene
- indol derivatives
- alkoxyl
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
DERIVADOS DE INDOL. LOS DERIVADOS DE INDOL DE FORMULA (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, DONDE R ES H, OH, HALO, ALQUILO C1-C4 O ALCOXILO C1-C4 ; R1, R2, R3 Y R4, SON H, OH, HALO, ALQUILO C1-C4, ALCOXILO C1-C4, -CF3, -CO2(ALQUILO C1-C4), -CONH2, -CONH(ALQUILO C1-C4) O -CON(ALQUILO C1-C4); R5 ES -COOH, -COOR7, -CONR8R9 O TETRAZOL-5-ILO; R6 ES UN RADICAL 1,3-BENZODIOXOLANO; X ES O, NH, N(ALQUILO C1-C4), UN ENLACE DIRECTO O ALQUILENO C1-C4, ALQUENILENO C2-C4 O ALQUINILENO C2-C4 OPCIONALMENTE SUSTITUIDOS; Y ES METILENO, ALQUILENO C2-C6, ALQUENILENO C2-C6 O ALQUINILENO C2-C6 O UN RADICAL CON UN CICLO DE 3 A 7 ATOMOS DE C, OPCIONALMENTE SUSTITUIDOS, SON INHIBIDORES DE LA 5AL-REDUCTASA DE ESTEROIDES Y SON UTILES PARA EL TRATAMIENTO DEL ACNE VULGAR, ALOPECIA, SEBORREA, HIRSUTISMO, HIPERTROFIA PROSTATICA BENIGNA, CALVICIE ANDROGENICA Y ADENOCARCINOMA PROSTATICO HUMANO.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9301604A ES2099007B1 (es) | 1993-07-16 | 1993-07-16 | Derivados de indol. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9301604A ES2099007B1 (es) | 1993-07-16 | 1993-07-16 | Derivados de indol. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2099007A1 true ES2099007A1 (es) | 1997-05-01 |
ES2099007B1 ES2099007B1 (es) | 1997-12-01 |
Family
ID=8282581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9301604A Expired - Fee Related ES2099007B1 (es) | 1993-07-16 | 1993-07-16 | Derivados de indol. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2099007B1 (es) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3843683A (en) * | 1968-02-20 | 1974-10-22 | Sterling Drug Inc | Alpha-(3-(4-chlorobenzoyl)-2-methyl-6-methoxy-1-ndole)-acetic acid |
US5013732A (en) * | 1984-08-06 | 1991-05-07 | Sterling Drug Inc. | 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles |
EP0445781A1 (en) * | 1990-03-08 | 1991-09-11 | Sterling Winthrop Inc. | 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions |
WO1993017014A1 (en) * | 1992-02-28 | 1993-09-02 | Pfizer Limited | Indole derivatives as steroid 5 alpha-reductase inhibitors |
-
1993
- 1993-07-16 ES ES9301604A patent/ES2099007B1/es not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3843683A (en) * | 1968-02-20 | 1974-10-22 | Sterling Drug Inc | Alpha-(3-(4-chlorobenzoyl)-2-methyl-6-methoxy-1-ndole)-acetic acid |
US5013732A (en) * | 1984-08-06 | 1991-05-07 | Sterling Drug Inc. | 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles |
EP0445781A1 (en) * | 1990-03-08 | 1991-09-11 | Sterling Winthrop Inc. | 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions |
WO1993017014A1 (en) * | 1992-02-28 | 1993-09-02 | Pfizer Limited | Indole derivatives as steroid 5 alpha-reductase inhibitors |
Non-Patent Citations (1)
Title |
---|
YOUNG, T.E. y MIZIANTY, M.F.: "Biindolyls. III. Substituted 2,3'-Biindolyls from 3-arylacetylindoles." Journal of organic Chemistry, Vol. 29, 1964, pßginas 2030-2031 * Compuestos Ic,Id * * |
Also Published As
Publication number | Publication date |
---|---|
ES2099007B1 (es) | 1997-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19970501 Kind code of ref document: A1 Effective date: 19970501 |
|
FD1A | Patent lapsed |
Effective date: 20050718 |