ES2092844T3 - Uso de derivados de piridoxal para la preparacion de un medicamento para el tratamiento de cataratas. - Google Patents

Uso de derivados de piridoxal para la preparacion de un medicamento para el tratamiento de cataratas.

Info

Publication number
ES2092844T3
ES2092844T3 ES94104943T ES94104943T ES2092844T3 ES 2092844 T3 ES2092844 T3 ES 2092844T3 ES 94104943 T ES94104943 T ES 94104943T ES 94104943 T ES94104943 T ES 94104943T ES 2092844 T3 ES2092844 T3 ES 2092844T3
Authority
ES
Spain
Prior art keywords
piridoxal
cataracts
medication
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94104943T
Other languages
English (en)
Inventor
Kazumi Ogata
Shunji Sogo
Eri Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2092844T3 publication Critical patent/ES2092844T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN USO NUEVO DEL COMPUESTO DE LA FORMULA EN LA QUE R1 ES UN ATOMO DE HIDROGENO O ALKILO INFERIOR Y R2 ES UN ATOMO DE HIDROGENO O UN GRUPO DE ACIDO FOSFORICO O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO PARA LA PREVENCION Y TRATAMIENTO DE CATARATAS. LOS COMPUESTOS DE LA FORMULA (I) Y LAS SALES FARMACOLOGICAMENTE ACEPTABLES DE LOS MISMOS DE LA PRESENTE INVENCION INHIBEN LOS CAMBIOS INICIALES DE LAS LENTES TALES COMO EL CAMBIO DE VACUOLACION Y TROCOIDE E INHIBEN CASI POR COMPLETO UN DESCENSO EN LAS CANTIDADES DE GLUTATIONA Y CISTEINAS REDUCIDAS DE LAS LENTES, POR LO QUE SE PUEDEN UTILIZAR CONVENIENTEMENTE PARA LA PREVENCION DEL INICIO Y AVANCE DE LAS CATARATAS.
ES94104943T 1993-04-02 1994-03-29 Uso de derivados de piridoxal para la preparacion de un medicamento para el tratamiento de cataratas. Expired - Lifetime ES2092844T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7649093 1993-04-02

Publications (1)

Publication Number Publication Date
ES2092844T3 true ES2092844T3 (es) 1996-12-01

Family

ID=13606667

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94104943T Expired - Lifetime ES2092844T3 (es) 1993-04-02 1994-03-29 Uso de derivados de piridoxal para la preparacion de un medicamento para el tratamiento de cataratas.

Country Status (7)

Country Link
US (1) US5441972A (es)
EP (1) EP0617960B1 (es)
AT (1) ATE144140T1 (es)
CA (1) CA2120300A1 (es)
DE (1) DE69400723T2 (es)
ES (1) ES2092844T3 (es)
TW (1) TW268948B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
DE60023125T2 (de) 1999-03-08 2006-06-22 University Of Manitoba, Winnipeg Pyridoxal-analoge zur behandlung von störungen ausgelöst durch einen vitamin b6 mangel
US6489345B1 (en) 1999-07-13 2002-12-03 Medicure, Inc. Treatment of diabetes and related pathologies
EP1872797A3 (en) * 1999-08-24 2008-04-02 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
DE60110054T2 (de) 2000-02-29 2006-03-09 Medicure International Inc. Cardioprotektive phosphonate
AU784840B2 (en) 2000-03-28 2006-07-06 Medicure International Inc. Treatment of cerebrovascular disease
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US6897228B2 (en) * 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
WO2002004421A2 (en) 2000-07-07 2002-01-17 Medicure International Inc. Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
US20040121988A1 (en) * 2001-03-28 2004-06-24 Medicure International Inc. Treatment of cerebrovascular disease
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
EP1773370A1 (en) * 2004-07-07 2007-04-18 Medicure International Inc. Combination therapies employing platelet aggregation drugs
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
CA2585165A1 (en) * 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
AU2006317440A1 (en) * 2005-11-28 2007-05-31 Medicure International Inc. Selected dosage for the treatment of cardiovascular and related pathologies

Also Published As

Publication number Publication date
ATE144140T1 (de) 1996-11-15
EP0617960B1 (en) 1996-10-16
TW268948B (es) 1996-01-21
CA2120300A1 (en) 1994-10-03
EP0617960A1 (en) 1994-10-05
DE69400723D1 (de) 1996-11-21
DE69400723T2 (de) 1997-03-20
US5441972A (en) 1995-08-15

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