ES2091267T3 - Substratos enzimaticos de acridinona cromogena. - Google Patents
Substratos enzimaticos de acridinona cromogena.Info
- Publication number
- ES2091267T3 ES2091267T3 ES91113550T ES91113550T ES2091267T3 ES 2091267 T3 ES2091267 T3 ES 2091267T3 ES 91113550 T ES91113550 T ES 91113550T ES 91113550 T ES91113550 T ES 91113550T ES 2091267 T3 ES2091267 T3 ES 2091267T3
- Authority
- ES
- Spain
- Prior art keywords
- enzyme
- hydroxy
- acridinone
- enzyme substrate
- acridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/40—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving amylase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/64—Acridine or hydrogenated acridine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
Abstract
COMPUESTOS DE SUSTRATOS DE ENZIMAS DE ACRIDINONA CROMOGENICA QUE CONTIENEN CROMOGENES DE 7-HIDROXI-9H-ACRIDINA-2-ONA DERIVADOS EN LA POSICION 7 -HIDROXI CON UN GRUPO QUE PUEDE DIVIDIRSE ENZIMATICAMENTE Y DISUSTITUIDO EN LA POSICION 9 CON GRUPOS ALQUILO O ARILO, QUE PUEDEN SER IGUALES O DIFERENTES, PREFERIBLEMENTE ALQUILO INFERIOR O FENILO, RESPECTIVAMENTE, O JUNTOS FORMAN UN RESIDUO DE CICLOHEXA-2, 5-DIEN-4-ONA O UN RESIDUO DE 4 -HIDROXICICLOHEXILO, E INTERMEDIOS DE 7-HIDROXI-1, 3-DIHALO-9, 9-DIMETIL -ACRIDIN-2-ONA UTILES PARA PREPARAR LOS NUEVOS COMPUESTOS DE SUSTRATO DE ENZIMA DE ACRIDINONA CROMOGENICA Y METODOS PARA ELLO. EL GRUPO QUE PUEDE DIVIDIRSE ENZIMATICAMENTE ES UN RADICAL DE UN COMPUESTO Y-OH QUE COMPRENDE UNA MITAD DE ENZIMA ESPECIFICA QUE PUEDE DIVIDIRSE MEDIANTE UNA ENZIMA ESPECIFICA EN LA QUE SE LIBERA UNA FORMA DESPROTONADA DEL CROMOGEN CON UNA ABSORBENCIA MAXIMA EN UNA SOLUCION BASICA QUE ES SUSTANCIALMENTE MAYOR QUE LA ABSORBENCIA MAXIMA DEL COMPUESTO DE SUSTRATO DE ENZIMADE ACRIDINONA CROMOGENICA PARA FACILITAR UN CAMBIO DISTINTO EN LA ABSORBENCIA QUE PUEDE SER MEDIDO CON PRECISION Y CORRELACIONADO CON LA CANTIDAD DE ENZIMA PRESENTE EN UNA MUESTRA DE ANALISIS LIQUIDO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93985586A | 1986-12-09 | 1986-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2091267T3 true ES2091267T3 (es) | 1996-11-01 |
Family
ID=25473855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91113550T Expired - Lifetime ES2091267T3 (es) | 1986-12-09 | 1987-11-27 | Substratos enzimaticos de acridinona cromogena. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0459536B1 (es) |
JP (1) | JPH0662569B2 (es) |
AT (1) | ATE142202T1 (es) |
AU (1) | AU585472B2 (es) |
DE (2) | DE3751896T2 (es) |
DK (1) | DK643887A (es) |
ES (1) | ES2091267T3 (es) |
IE (1) | IE60183B1 (es) |
IL (1) | IL84666A (es) |
NO (1) | NO175308C (es) |
ZA (1) | ZA879223B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7183069B2 (en) | 2002-03-07 | 2007-02-27 | Toyama University | Reagent, method and apparatus for measuring amylase activity |
US7186696B2 (en) * | 2002-03-07 | 2007-03-06 | Toyama University | Reagent and method for measuring amylase |
FR2850378B1 (fr) * | 2003-01-29 | 2005-03-04 | Bio Merieux | Substrats enzymatiques, milieux de culture les contenant, utilisation pour detecter une activite aminopeptidase et/ou differencier des bacteries a gram+ par rapport a des bacteries a gram- |
EP2371927B1 (en) * | 2004-09-16 | 2020-03-11 | Life Technologies Corporation | Fluorescent dye compounds, conjugates and uses thereof |
EP2913408A1 (en) | 2010-12-29 | 2015-09-02 | Life Technologies Corporation | Ddao compounds as fluorescent reference standards |
-
1987
- 1987-11-27 EP EP91113550A patent/EP0459536B1/en not_active Expired - Lifetime
- 1987-11-27 DE DE3751896T patent/DE3751896T2/de not_active Expired - Fee Related
- 1987-11-27 AT AT91113550T patent/ATE142202T1/de not_active IP Right Cessation
- 1987-11-27 DE DE8787117548T patent/DE3779066D1/de not_active Expired - Fee Related
- 1987-11-27 ES ES91113550T patent/ES2091267T3/es not_active Expired - Lifetime
- 1987-12-01 IL IL84666A patent/IL84666A/xx not_active IP Right Cessation
- 1987-12-01 NO NO875008A patent/NO175308C/no not_active IP Right Cessation
- 1987-12-03 AU AU82060/87A patent/AU585472B2/en not_active Ceased
- 1987-12-08 ZA ZA879223A patent/ZA879223B/xx unknown
- 1987-12-08 DK DK643887A patent/DK643887A/da not_active Application Discontinuation
- 1987-12-08 IE IE333187A patent/IE60183B1/en not_active IP Right Cessation
- 1987-12-08 JP JP62308813A patent/JPH0662569B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO875008L (no) | 1988-06-10 |
EP0459536B1 (en) | 1996-09-04 |
JPH0662569B2 (ja) | 1994-08-17 |
DE3751896T2 (de) | 1997-01-16 |
AU585472B2 (en) | 1989-06-15 |
ZA879223B (en) | 1988-08-31 |
EP0459536A1 (en) | 1991-12-04 |
AU8206087A (en) | 1988-06-09 |
DE3751896D1 (de) | 1996-10-10 |
IE873331L (en) | 1988-06-09 |
IL84666A0 (en) | 1988-05-31 |
DK643887D0 (da) | 1987-12-08 |
NO875008D0 (no) | 1987-12-01 |
ATE142202T1 (de) | 1996-09-15 |
DK643887A (da) | 1988-06-10 |
IL84666A (en) | 1992-02-16 |
JPH01131192A (ja) | 1989-05-24 |
IE60183B1 (en) | 1994-06-15 |
NO175308B (no) | 1994-06-20 |
DE3779066D1 (en) | 1992-06-17 |
NO175308C (no) | 1994-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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