ES2087186T3 - Nuevas piperidinas sustituidas y su empleo como inhibidores de la sintesis de colesterol. - Google Patents
Nuevas piperidinas sustituidas y su empleo como inhibidores de la sintesis de colesterol.Info
- Publication number
- ES2087186T3 ES2087186T3 ES91112343T ES91112343T ES2087186T3 ES 2087186 T3 ES2087186 T3 ES 2087186T3 ES 91112343 T ES91112343 T ES 91112343T ES 91112343 T ES91112343 T ES 91112343T ES 2087186 T3 ES2087186 T3 ES 2087186T3
- Authority
- ES
- Spain
- Prior art keywords
- chesterol
- substituted piperidines
- synthesis inhibitors
- new substituted
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
ESTA INVENCION SE REFIERE A UN GRUPO DE COMPUESTOS QUE SON NUEVAS PIPERIDINAS SUSTITUIDAS Y QUE ACTUAN PARA INHIBIR LA SINTESIS DEL COLESTEROL EN MAMIFEROS Y EN HONGOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55785590A | 1990-07-24 | 1990-07-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2087186T3 true ES2087186T3 (es) | 1996-07-16 |
Family
ID=24227150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91112343T Expired - Lifetime ES2087186T3 (es) | 1990-07-24 | 1991-07-23 | Nuevas piperidinas sustituidas y su empleo como inhibidores de la sintesis de colesterol. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0468457B1 (es) |
JP (1) | JP3072923B2 (es) |
KR (1) | KR100198178B1 (es) |
CN (1) | CN1058394A (es) |
AT (1) | ATE134997T1 (es) |
AU (1) | AU638852B2 (es) |
CA (1) | CA2047389C (es) |
DE (1) | DE69117607T2 (es) |
ES (1) | ES2087186T3 (es) |
FI (1) | FI913532A (es) |
HU (1) | HUT58289A (es) |
IE (1) | IE912588A1 (es) |
IL (1) | IL98919A0 (es) |
NO (1) | NO912875L (es) |
NZ (1) | NZ239023A (es) |
PT (1) | PT98424A (es) |
ZA (1) | ZA915660B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5348964A (en) * | 1990-07-25 | 1994-09-20 | Merrell Dow Pharmaceuticals Inc. | Piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis |
US5350758A (en) * | 1992-07-08 | 1994-09-27 | Merrell Dow Pharmaceuticals Inc. | Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis |
FR2697250B1 (fr) * | 1992-10-28 | 1995-01-20 | Fournier Ind & Sante | Dérivés de beta,beta-diméthyl-4-pipéridineéthanol et de 1,2,3,6-tétrahydro-beta,beta-diméthyl-4-pyridineéthanol, leur procédé de préparation et leur utilisation en thérapeutique. |
FR2705343B1 (fr) * | 1993-05-17 | 1995-07-21 | Fournier Ind & Sante | Dérivés de beta,beta-diméthyl-4-pipéridineéthanamine, leur procédé de préparation et leur utilisation en thérapeutique. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3178439A (en) * | 1963-05-06 | 1965-04-13 | Reilly Tar & Chem Corp | N-alkanoyl and alkenoyl hydroxy alkyl piperidides |
DE3433036A1 (de) * | 1984-09-08 | 1986-03-20 | Basf Ag, 6700 Ludwigshafen | Piperidinderivate und diese enthaltende fungizide sowie verfahren zur bekaempfung von pilzen |
DE3708033A1 (de) * | 1987-03-12 | 1988-09-22 | Bayer Ag | Mittel zur insekten- und milbenabwehr |
CA1337418C (en) * | 1988-03-28 | 1995-10-24 | Engelbert Ciganek | 4-aryl-4-piperiding (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof |
ZA899436B (en) * | 1988-12-12 | 1990-08-29 | Ciba Geigy | Piperidine derivatives |
-
1991
- 1991-07-18 AU AU81111/91A patent/AU638852B2/en not_active Ceased
- 1991-07-18 CA CA002047389A patent/CA2047389C/en not_active Expired - Fee Related
- 1991-07-18 NZ NZ239023A patent/NZ239023A/en unknown
- 1991-07-18 ZA ZA915660A patent/ZA915660B/xx unknown
- 1991-07-22 IL IL98919A patent/IL98919A0/xx unknown
- 1991-07-23 AT AT91112343T patent/ATE134997T1/de not_active IP Right Cessation
- 1991-07-23 ES ES91112343T patent/ES2087186T3/es not_active Expired - Lifetime
- 1991-07-23 EP EP91112343A patent/EP0468457B1/en not_active Expired - Lifetime
- 1991-07-23 IE IE258891A patent/IE912588A1/en unknown
- 1991-07-23 PT PT98424A patent/PT98424A/pt not_active Application Discontinuation
- 1991-07-23 KR KR1019910012637A patent/KR100198178B1/ko not_active IP Right Cessation
- 1991-07-23 HU HU912469A patent/HUT58289A/hu unknown
- 1991-07-23 FI FI913532A patent/FI913532A/fi unknown
- 1991-07-23 NO NO91912875A patent/NO912875L/no unknown
- 1991-07-23 DE DE69117607T patent/DE69117607T2/de not_active Expired - Fee Related
- 1991-07-24 JP JP03206242A patent/JP3072923B2/ja not_active Expired - Fee Related
- 1991-07-24 CN CN91105085A patent/CN1058394A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69117607D1 (de) | 1996-04-11 |
IL98919A0 (en) | 1992-07-15 |
DE69117607T2 (de) | 1996-08-01 |
JPH04234363A (ja) | 1992-08-24 |
FI913532A (fi) | 1992-01-25 |
HUT58289A (en) | 1992-02-28 |
NO912875L (no) | 1992-01-27 |
HU912469D0 (en) | 1991-12-30 |
KR920002569A (ko) | 1992-02-28 |
JP3072923B2 (ja) | 2000-08-07 |
IE912588A1 (en) | 1992-01-29 |
EP0468457B1 (en) | 1996-03-06 |
CA2047389C (en) | 2002-04-23 |
NO912875D0 (no) | 1991-07-23 |
CA2047389A1 (en) | 1992-01-25 |
FI913532A0 (fi) | 1991-07-23 |
CN1058394A (zh) | 1992-02-05 |
KR100198178B1 (ko) | 1999-06-15 |
AU638852B2 (en) | 1993-07-08 |
ZA915660B (en) | 1992-05-27 |
AU8111191A (en) | 1992-01-30 |
NZ239023A (en) | 1993-12-23 |
PT98424A (pt) | 1992-05-29 |
ATE134997T1 (de) | 1996-03-15 |
EP0468457A1 (en) | 1992-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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