ES2081989T3 - Tratamiento para reducir el edema en lesiones cerebrales y musculares. - Google Patents

Tratamiento para reducir el edema en lesiones cerebrales y musculares.

Info

Publication number
ES2081989T3
ES2081989T3 ES90909011T ES90909011T ES2081989T3 ES 2081989 T3 ES2081989 T3 ES 2081989T3 ES 90909011 T ES90909011 T ES 90909011T ES 90909011 T ES90909011 T ES 90909011T ES 2081989 T3 ES2081989 T3 ES 2081989T3
Authority
ES
Spain
Prior art keywords
brain
edema
corticotropin
musculature
injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909011T
Other languages
English (en)
Inventor
Edward T Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Application granted granted Critical
Publication of ES2081989T3 publication Critical patent/ES2081989T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2228—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA ADMINISTRACION DE UN FACTOR DE LIBERACION DE LA CORTICOTROPINA (O UNA SAL O ANALOGO DEL MISMO) HACE QUE DISMINUYA EL DERRAME DE COMPONENTES SANGUINEOS EN EL TEJIDO CEREBRAL DEBIDO A VARIAS CONDICIONES MEDICAS ADVERSAS Y REDUCE EL SANGRADO CUANDO LOS TEJIDOS MUSCULARES SE CORTAN O MANEJAN, COMO POR EJEMPLO EN LA CIRUGIA PLASTICA O RECONSTITUYENTE. UN METODO PARA TRATAR A UN PACIENTE QUE SUFRE UNA LESION O UNA ENFERMEDAD EN EL CEREBRO, EN EL SISTEMA NERVIOSO CENTRAL O EN LA MUSCULATURA EN QUE UN EDEMA ES UN FACTOR CONSISTE EN ADMINISTRAR AL PACIENTE UN FACTOR DE LIBERACION DE LA CORTICOTROPINA (O UNA SAL O ANALOGO) EN UNA CANTIDAD EFECTIVA PARA DISMINUIR LA PERMEABILIDAD VASCULAR EN EL CEREBRO ENFERMO O LESIONADO, EN EL TEJIDO DEL SISTEMA NERVIOSO O EN LA MUSCULATURA PARA ASI REDUCIR EL EDEMA. SEGUN EL METODO LA ADMINISTRACION PUEDE TENER LUGAR UNAS DOS HORAS ANTES DE LA OPERACION Y SE PUEDE SEGUIR ADMINISTRANDO HASTA TRES DIAS DESPUES DE LA LESION.
ES90909011T 1989-07-28 1990-05-30 Tratamiento para reducir el edema en lesiones cerebrales y musculares. Expired - Lifetime ES2081989T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/386,885 US5137871A (en) 1989-07-28 1989-07-28 Treatment to reduce edema for brain and musculature injuries

Publications (1)

Publication Number Publication Date
ES2081989T3 true ES2081989T3 (es) 1996-03-16

Family

ID=23527476

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909011T Expired - Lifetime ES2081989T3 (es) 1989-07-28 1990-05-30 Tratamiento para reducir el edema en lesiones cerebrales y musculares.

Country Status (11)

Country Link
US (2) US5137871A (es)
EP (1) EP0484340B1 (es)
JP (1) JP3012319B2 (es)
AT (1) ATE131064T1 (es)
AU (1) AU641166B2 (es)
CA (1) CA2064039C (es)
DE (1) DE69024053T2 (es)
DK (1) DK0484340T3 (es)
ES (1) ES2081989T3 (es)
IE (1) IE63053B1 (es)
WO (1) WO1991001997A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5488033A (en) * 1989-07-28 1996-01-30 The Regents Of The University Of California Treatment to reduce edema
US5137871A (en) * 1989-07-28 1992-08-11 Regents Of The University Of California Treatment to reduce edema for brain and musculature injuries
US5374621A (en) * 1991-09-13 1994-12-20 Regents Of The University Of California Neurotensin method for inhibiting vascular leakage
EP0781140A4 (en) * 1994-09-12 1999-11-03 Univ Pennsylvania FACTOR INHIBITING THE CORTICOTROPIN RELEASE AND METHOD FOR ITS USE
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
US5869450A (en) * 1996-03-06 1999-02-09 The Regents Of The University Of California Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
US6011066A (en) * 1998-02-02 2000-01-04 Veterans General Hospital-Taipei Method for treating septic shock
WO2000037502A2 (en) * 1998-12-22 2000-06-29 Genentech, Inc. Vascular endothelial cell growth factor antagonists and uses thereof
US6849600B2 (en) * 2002-03-25 2005-02-01 The Regents Of The University Of California, Berkeley Corticotropin-releasing hormone analogs
WO2006021814A2 (en) * 2004-07-08 2006-03-02 Aimsco Limited Medicament
GB0415359D0 (en) * 2004-07-08 2004-08-11 Aimsco Ltd Medicament
GB0600202D0 (en) * 2006-01-06 2006-02-15 Aimsco Ltd Treatment of HIV
US7455447B2 (en) * 2006-05-19 2008-11-25 Mediatek Inc. Method and apparatus for a portable device
WO2010033207A1 (en) 2008-09-19 2010-03-25 Nektar Therapeutics Polymer conjugates of therapeutic peptides
WO2013169939A2 (en) 2012-05-08 2013-11-14 Aeromics, Llc New methods
WO2015069961A1 (en) 2013-11-06 2015-05-14 Aeromics, Llc Novel prodrug salts

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980778A (en) * 1973-10-25 1976-09-14 The Upjohn Company Anti-inflammatory steroid
US4579844A (en) * 1976-05-13 1986-04-01 Johnson & Johnson Topical anti-inflammatory drug therapy
US4404198A (en) * 1979-01-24 1983-09-13 Beecham Inc. Phenyl Salicylate as a topical anti-inflammatory
US4415558A (en) * 1981-06-08 1983-11-15 The Salk Institute For Biological Studies CRF And analogs
US4517181A (en) * 1982-09-15 1985-05-14 The Salk Institute For Biological Studies Mammalian PGRF
EP0120000A1 (en) * 1982-09-29 1984-10-03 LEDERIS, Karl P. Urotensin peptides
US4528189A (en) * 1983-02-03 1985-07-09 The Salk Institute For Biological Studies Urotensin peptides
US4489163A (en) * 1983-04-14 1984-12-18 The Salk Institute For Biological Studies rCRF and analogs
US4605642A (en) * 1984-02-23 1986-08-12 The Salk Institute For Biological Studies CRF antagonists
US4594329A (en) * 1984-05-14 1986-06-10 The Salk Institute For Biological Studies CRF analogs
US4801612A (en) * 1986-07-03 1989-01-31 Regents Of The University Of California Method of inhibiting inflammatory response
US5137871A (en) * 1989-07-28 1992-08-11 Regents Of The University Of California Treatment to reduce edema for brain and musculature injuries

Also Published As

Publication number Publication date
JPH05501856A (ja) 1993-04-08
DK0484340T3 (da) 1996-04-22
CA2064039A1 (en) 1991-01-29
DE69024053T2 (de) 1996-07-04
EP0484340A1 (en) 1992-05-13
AU641166B2 (en) 1993-09-16
US5306710A (en) 1994-04-26
AU5749290A (en) 1991-03-11
JP3012319B2 (ja) 2000-02-21
WO1991001997A1 (en) 1991-02-21
US5137871A (en) 1992-08-11
CA2064039C (en) 2001-01-02
ATE131064T1 (de) 1995-12-15
EP0484340B1 (en) 1995-12-06
DE69024053D1 (de) 1996-01-18
IE63053B1 (en) 1995-03-22
EP0484340A4 (en) 1993-02-17
IE902737A1 (en) 1991-02-27

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