ES2078893T3 - Sistema de entrega de drogas transdermica pulsatoria. - Google Patents

Sistema de entrega de drogas transdermica pulsatoria.

Info

Publication number
ES2078893T3
ES2078893T3 ES88108314T ES88108314T ES2078893T3 ES 2078893 T3 ES2078893 T3 ES 2078893T3 ES 88108314 T ES88108314 T ES 88108314T ES 88108314 T ES88108314 T ES 88108314T ES 2078893 T3 ES2078893 T3 ES 2078893T3
Authority
ES
Spain
Prior art keywords
patient
oscillator
skin
membrane
periodic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88108314T
Other languages
English (en)
Inventor
Dan Sibalis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Drug Delivery Systems Inc
Original Assignee
Drug Delivery Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drug Delivery Systems Inc filed Critical Drug Delivery Systems Inc
Application granted granted Critical
Publication of ES2078893T3 publication Critical patent/ES2078893T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J7/00—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
    • H02J7/007—Regulation of charging or discharging current or voltage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J2310/00—The network for supplying or distributing electric power characterised by its spatial reach or by the load
    • H02J2310/10—The network having a local or delimited stationary reach
    • H02J2310/20—The network being internal to a load
    • H02J2310/23—The load being a medical device, a medical implant, or a life supporting device
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J2310/00—The network for supplying or distributing electric power characterised by its spatial reach or by the load
    • H02J2310/40—The network being an on-board power network, i.e. within a vehicle
    • H02J2310/44—The network being an on-board power network, i.e. within a vehicle for aircrafts

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Power Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN SISTEMA DE ENTREGA DE DROGAS TRANSDERMICA ELECTROFORETICA / ELECTROOSMOTICA PARA PASAR AL MENOS UNA DROGA, O COMPONENTE TERAPEUTICO, A TRAVES DE LA PIEL (16) DE UN PACIENTE POR VIA DE UN DEPOSITO DE DROGA (12) O GEL PARA ENTREGA AL SISTEMA SANGUINEO DE UN PACIENTE EN PULSACIONES PERIODICAS SELECCIONADAS. EL SISTEMA PUEDE SER VARIADO PARA ACOMODARLO A VARIOS TIPOS DE COMPONENTES TERAPEUTICOS QUE TIENEN CARACTERISTICAS Y PROPOSITOS VARIADOS. EL SISTEMA INCLUYE UN OSCILADOR DE CORRIENTE (28) QUE APLICA VARIACIONES ELECTRICAS PERIODICAS AL SISTEMA EN ORDEN A PONER EN FUNCIONAMIENTO VARIACIONES RITMICAS DEL POTENCIAL Y RESISTENCIAS DE LA MEMBRANA DE LA PIEL PARA CAUSAR CARITACION ELECTRO - OSMOTICA OSCILATORIAMENTE DEL LIQUIDO CON EL COMPONENETE TERAPEUTICO A TRAVES DE LA MEMBRANA DE LA PIEL EN SINCRONIZACION CON EL OSCILADOR PARA EL SISTEMA SANGUINEO DEL PACIENTE EN RESPUESTA A LAS VARIACIONES RITMICAS. EL OSCILADOR CAUSA LA FUENTE DE POTENCIA (22) PARA ENTREGAR UNA CORRIENTE PULSATORIOPERIODICA.
ES88108314T 1987-05-28 1988-05-25 Sistema de entrega de drogas transdermica pulsatoria. Expired - Lifetime ES2078893T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5551887A 1987-05-28 1987-05-28

Publications (1)

Publication Number Publication Date
ES2078893T3 true ES2078893T3 (es) 1996-01-01

Family

ID=21998388

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88108314T Expired - Lifetime ES2078893T3 (es) 1987-05-28 1988-05-25 Sistema de entrega de drogas transdermica pulsatoria.

Country Status (10)

Country Link
EP (1) EP0292930B1 (es)
JP (1) JPH0647017B2 (es)
KR (1) KR960011032B1 (es)
AT (1) ATE129643T1 (es)
AU (1) AU615188B2 (es)
BR (1) BR8802589A (es)
CA (1) CA1299457C (es)
DE (1) DE3854631T2 (es)
ES (1) ES2078893T3 (es)
GR (1) GR3018864T3 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734090A (en) * 1986-07-18 1988-03-29 Drug Delivery Systems Inc. Electrical transdermal drug applicator
US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5334138A (en) * 1990-03-15 1994-08-02 North Carolina State University Method and composition for increased skin concentration of active agents by iontophoresis
US6004309A (en) * 1990-03-30 1999-12-21 Alza Corporation Method and apparatus for controlled environment electrotransport
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5213568A (en) * 1990-03-30 1993-05-25 Medtronic Inc. Activity controlled electrotransport drug delivery device
WO1996022810A1 (en) * 1995-01-27 1996-08-01 Alessandro Aloisi A device for ionophoresis physiotherapy with frozen medicament crystals
EP0941085B1 (en) * 1996-11-14 2003-04-23 Alza Corporation Device for electrically assisted delivery of agents such as lidocaine and epinephrine
US6295469B1 (en) 1997-11-14 2001-09-25 Alza Corporation Formulation for electrically assisted delivery of lidocaine and epinephrine
IT1307852B1 (it) 1999-03-22 2001-11-19 Africa Antonino D Un dispositivo per la somministrazione per via transcutanea dimolecole contenute in un prodotto veicolante relativamente viscoso,
IT1315207B1 (it) 1999-06-09 2003-02-03 Antonino D Africa Dispositvo e metodo per il trasporto molecolare transdermico.
IT1316594B1 (it) 2000-08-02 2003-04-24 Elisabetta Rossi Elettrodo e contenitore per la somministrazione per via transcutaneadi molecole contenute in un prodotto veicolante
IT1315449B1 (it) 2000-09-22 2003-02-11 Elisabetta Rossi Dispositivo e metodo per il trasporto molecolare transdermico
US6872292B2 (en) * 2003-01-28 2005-03-29 Microlin, L.C. Voltage modulation of advanced electrochemical delivery system
CN1994489B (zh) * 2006-12-22 2010-05-12 江西师范大学 调制超音频电场经皮给药装置
CN102512753B (zh) * 2011-12-22 2013-11-13 浙江大学 一种经皮给药电磁导入仪
FR3116951B1 (fr) * 2020-11-27 2023-08-25 Accumulateurs Fixes Dispositif d’inertage d’une batterie, bloc d’alimentation, système et procédé d’inertage associés
CN112999144B (zh) * 2021-01-27 2023-03-21 杭州医学院 一种离子电渗透经皮给药系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218255A (en) * 1976-08-30 1980-08-19 University Of Dayton Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/or other mamillian species and method
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
EP0060452B1 (en) * 1981-03-05 1985-10-23 Medtronic, Inc. Iontophoretic device
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
GB2175207B (en) * 1985-05-20 1989-07-05 Nabil Ibraham Rizk Improvements in or relating to implantable electrophoretic pumps
JPS61279257A (ja) * 1985-06-05 1986-12-10 林原　健 眉毛発育装置
CA1317522C (en) * 1987-03-20 1993-05-11 Dan Sibalis Transdermal drug delivery system

Also Published As

Publication number Publication date
BR8802589A (pt) 1988-12-20
GR3018864T3 (en) 1996-05-31
JPS63305879A (ja) 1988-12-13
KR960011032B1 (ko) 1996-08-16
CA1299457C (en) 1992-04-28
EP0292930A1 (en) 1988-11-30
DE3854631D1 (de) 1995-12-07
DE3854631T2 (de) 1996-06-20
AU615188B2 (en) 1991-09-26
AU1612588A (en) 1988-12-01
JPH0647017B2 (ja) 1994-06-22
ATE129643T1 (de) 1995-11-15
KR880013587A (ko) 1988-12-21
EP0292930B1 (en) 1995-11-02

Similar Documents

Publication Publication Date Title
ES2078893T3 (es) Sistema de entrega de drogas transdermica pulsatoria.
US5312325A (en) Pulsating transdermal drug delivery system
ES2051270T3 (es) Dispositivo de administracion transdermica de medicamentos.
DE3751917D1 (de) Iontotherapeutische vorrichtung mit dosiereinheit
BR9104777A (pt) Aparelho e processo para aplicar tratamento iontoforetico a um paciente biologico,aparelho em um sistema iontoforetico para infusao de substancias medicamentosas,aparelho para preparacao de superficie,aparelho para tirar perturbacoes ionicas de um sistema de ministracao de medicamentos,processo de infusao iontoforetica de substancias medicinais e processo em um sistema iontoforetico de ministracao de medicamentos
DE68901140D1 (de) Waessrige loesung von fettloeslichen wirkstoffen.
ES2012944A6 (es) Procedimiento y su dispositivo para la admionistracion de farmacos mediante ionoforesis, para tratamiento loco-regionales.
ATE49126T1 (de) Mittel zur transdermalen applikation von arzneistoffen.
DE3785103T2 (de) Elektrisches system zur transdermalen medikamentenverabreichung.
DE3586595D1 (de) Programmierbare kontrolle und bausystem eines verabreichungsgeraetes fuer transdermische arzneien.
DE69121885T2 (de) Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten
DE69312916D1 (de) Wirkstoffabgabevorrichtungen
MX173932B (es) Sistema electro-osmotico transdermico de suministro de droga
BR0011459A (pt) Dispositivo ionoforético de liberação de droga
ES2136605T3 (es) Dispositivo electrico de aplicacion transdermica de farmacos con un agente de contrarresto.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 292930

Country of ref document: ES