ES2075191T3 - 1-(3-(2-hidroxi-3-alquilaminopropoxi)-2-tienil)-3-fenil-1-propanonas y procedimiento para su preparacion. - Google Patents
1-(3-(2-hidroxi-3-alquilaminopropoxi)-2-tienil)-3-fenil-1-propanonas y procedimiento para su preparacion.Info
- Publication number
- ES2075191T3 ES2075191T3 ES90890015T ES90890015T ES2075191T3 ES 2075191 T3 ES2075191 T3 ES 2075191T3 ES 90890015 T ES90890015 T ES 90890015T ES 90890015 T ES90890015 T ES 90890015T ES 2075191 T3 ES2075191 T3 ES 2075191T3
- Authority
- ES
- Spain
- Prior art keywords
- propanonas
- alquilaminopropoxi
- tienil
- hidroxi
- fenil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
EL INVENTO SE REFIERE A UN NUEVO DERIVADO DE 1-(3-(2-HIDROXI-3-ALQUILAMINO PROPOXI)-2-TIENILO)-3-FENILO-1-PROPAMONA DE FORMULA (I) Y DESCRIBE LA APLICACION DEL COMPUESTO DE FORMULA (I) PARA EL TRATAMIENTO DE ARRITMIAS. SIENDO; R1 ALQUILO, ARILO, HETEROARILO (TIENILO, FURILO, PIRIDILO), ALQUILARILO, ALQUILHETEROARILO DE C1 A 5 SATURADOS O INSATURADOS Y R2 ALQUILO DE BAJO PESO MOLECULAR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT130/89A AT392967B (de) | 1989-01-24 | 1989-01-24 | Neue 1-(3-(2-hydroxy-3-alkylaminopropoxy)-2- thienyl)-3-phenyl-1-propanone und verfahren zu deren herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075191T3 true ES2075191T3 (es) | 1995-10-01 |
Family
ID=3482324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90890015T Expired - Lifetime ES2075191T3 (es) | 1989-01-24 | 1990-01-23 | 1-(3-(2-hidroxi-3-alquilaminopropoxi)-2-tienil)-3-fenil-1-propanonas y procedimiento para su preparacion. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4994484A (es) |
EP (1) | EP0381661B1 (es) |
JP (1) | JPH02233677A (es) |
AT (1) | AT392967B (es) |
CA (1) | CA2007785C (es) |
DE (1) | DE59009107D1 (es) |
DK (1) | DK0381661T3 (es) |
ES (1) | ES2075191T3 (es) |
GR (1) | GR3017119T3 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3907512C2 (de) * | 1989-03-08 | 1997-08-14 | Laevosan Gmbh & Co Kg | Neue Aryloxy-alkylamine, deren Herstellung und diese enthaltende Arzneimittel |
US5891885A (en) * | 1996-10-09 | 1999-04-06 | Algos Pharmaceutical Corporation | Method for treating migraine |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7232924B2 (en) | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1266119B (de) * | 1963-03-19 | 1968-04-11 | Waertsilae Yhtymae O Y Waertsi | Trockenzylinder fuer Papiermaschinen |
US3614983A (en) * | 1969-04-09 | 1971-10-26 | Johnson Corp | Internal small bore roll syphon |
AT369739B (de) * | 1980-11-28 | 1983-01-25 | Laevosan Gmbh & Co Kg | Verfahren zur herstellung neuer 1-(3-(2-hydroxy-3alkylaminopropoxy)-2-thienyl)-3-phenyl-1- propanone und ihrer saeureadditionssalze |
DE3316155A1 (de) * | 1983-05-03 | 1984-11-08 | Helopharm W. Petrik & Co Kg, 1000 Berlin | 2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittel |
JPS62178585A (ja) * | 1986-01-29 | 1987-08-05 | レフオ−サン−ゲゼルシヤフト エム・ベ−・ハ− | 1−〔3−(2−ヒドロキシ−3−アルキルアミノプロポキシ)−2−チエニル〕−3−フエニル−1−プロパノン及びそれらの酸付加塩並びにそれらの製造法及びそれらを含む薬学的組成物 |
DE3770117D1 (de) * | 1986-10-29 | 1991-06-20 | Binder Dieter | Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3-phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
-
1989
- 1989-01-24 AT AT130/89A patent/AT392967B/de not_active IP Right Cessation
-
1990
- 1990-01-15 CA CA002007785A patent/CA2007785C/en not_active Expired - Fee Related
- 1990-01-23 EP EP90890015A patent/EP0381661B1/de not_active Expired - Lifetime
- 1990-01-23 ES ES90890015T patent/ES2075191T3/es not_active Expired - Lifetime
- 1990-01-23 DK DK90890015.2T patent/DK0381661T3/da not_active Application Discontinuation
- 1990-01-23 DE DE59009107T patent/DE59009107D1/de not_active Expired - Fee Related
- 1990-01-24 JP JP2012770A patent/JPH02233677A/ja active Pending
- 1990-01-24 US US07/469,893 patent/US4994484A/en not_active Expired - Fee Related
-
1995
- 1995-08-16 GR GR950402238T patent/GR3017119T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AT392967B (de) | 1991-07-25 |
ATA13089A (de) | 1990-12-15 |
EP0381661A1 (de) | 1990-08-08 |
DK0381661T3 (da) | 1995-10-09 |
CA2007785C (en) | 1996-09-03 |
JPH02233677A (ja) | 1990-09-17 |
CA2007785A1 (en) | 1990-07-24 |
DE59009107D1 (de) | 1995-06-29 |
US4994484A (en) | 1991-02-19 |
GR3017119T3 (en) | 1995-11-30 |
EP0381661B1 (de) | 1995-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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