ES2066147T3 - Derivados de la 1,4-dihidro-4-oxo-3-quinolina como agentes antibacterianos en mamiferos selectivamente toxicos. - Google Patents

Derivados de la 1,4-dihidro-4-oxo-3-quinolina como agentes antibacterianos en mamiferos selectivamente toxicos.

Info

Publication number
ES2066147T3
ES2066147T3 ES90310576T ES90310576T ES2066147T3 ES 2066147 T3 ES2066147 T3 ES 2066147T3 ES 90310576 T ES90310576 T ES 90310576T ES 90310576 T ES90310576 T ES 90310576T ES 2066147 T3 ES2066147 T3 ES 2066147T3
Authority
ES
Spain
Prior art keywords
mammals
antibacterial agents
quinoline
dihydro
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90310576T
Other languages
English (en)
Inventor
Paul R Mcguirk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of ES2066147T3 publication Critical patent/ES2066147T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

COMPUESTOS DE LA FORMULA Y LAS SALES FRAMACEUTICAMENTE ACEPTABLES DE ELLA, EN DONDE Q, X Y R SON COMO SE DEFINEN EN LA MEMORIA. LOS COMPUESTOS DE FORMULA I SON AGENTES ANTIBACTERIANOS DE AMPLIO ESPECTRO PARA MAMIFEROS Y EXHIBEN SELECTIVIDAD FAVORABLE CONTRA CELULAS PROCARIOTAS.
ES90310576T 1989-10-06 1990-09-27 Derivados de la 1,4-dihidro-4-oxo-3-quinolina como agentes antibacterianos en mamiferos selectivamente toxicos. Expired - Lifetime ES2066147T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/004438 WO1991004972A1 (en) 1989-10-06 1989-10-06 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents

Publications (1)

Publication Number Publication Date
ES2066147T3 true ES2066147T3 (es) 1995-03-01

Family

ID=22215279

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90310576T Expired - Lifetime ES2066147T3 (es) 1989-10-06 1990-09-27 Derivados de la 1,4-dihidro-4-oxo-3-quinolina como agentes antibacterianos en mamiferos selectivamente toxicos.

Country Status (12)

Country Link
EP (1) EP0421668B1 (es)
JP (1) JPH03130286A (es)
AT (1) ATE116649T1 (es)
CA (1) CA2026972A1 (es)
DE (1) DE69015756T2 (es)
DK (1) DK0421668T3 (es)
ES (1) ES2066147T3 (es)
FI (1) FI921475L (es)
GR (1) GR3015002T3 (es)
IE (1) IE64194B1 (es)
PT (1) PT95519B (es)
WO (1) WO1991004972A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
US7902227B2 (en) * 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
IN166416B (es) * 1985-09-18 1990-05-05 Pfizer
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
AU618235B2 (en) * 1986-03-31 1991-12-19 Sankyo Company Limited Quinoline-3-carboxylic acid derivatives, their preparation and use
JPS63198664A (ja) * 1986-03-31 1988-08-17 Sankyo Co Ltd キノロンカルボン酸誘導体
DE3641312A1 (de) * 1986-12-03 1988-06-09 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
DE3713672A1 (de) * 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent

Also Published As

Publication number Publication date
CA2026972A1 (en) 1991-04-07
IE64194B1 (en) 1995-07-12
IE903566A1 (en) 1991-04-10
WO1991004972A1 (en) 1991-04-18
FI921475A0 (fi) 1992-04-03
JPH03130286A (ja) 1991-06-04
DK0421668T3 (da) 1995-03-20
DE69015756T2 (de) 1995-05-11
EP0421668A2 (en) 1991-04-10
FI921475A7 (fi) 1992-04-03
GR3015002T3 (en) 1995-05-31
ATE116649T1 (de) 1995-01-15
PT95519B (pt) 1997-07-31
EP0421668B1 (en) 1995-01-04
DE69015756D1 (de) 1995-02-16
EP0421668A3 (en) 1991-08-07
PT95519A (pt) 1991-08-14
FI921475L (fi) 1992-04-03

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