ES2062860T3 - Composicion farmaceutica para la mejoria de la disuria. - Google Patents

Composicion farmaceutica para la mejoria de la disuria.

Info

Publication number
ES2062860T3
ES2062860T3 ES92121075T ES92121075T ES2062860T3 ES 2062860 T3 ES2062860 T3 ES 2062860T3 ES 92121075 T ES92121075 T ES 92121075T ES 92121075 T ES92121075 T ES 92121075T ES 2062860 T3 ES2062860 T3 ES 2062860T3
Authority
ES
Spain
Prior art keywords
group
atoms
carbon
dysuria
miction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92121075T
Other languages
English (en)
Inventor
Yuko Morioka
Mitsuru Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Hoechst Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan Ltd filed Critical Hoechst Japan Ltd
Application granted granted Critical
Publication of ES2062860T3 publication Critical patent/ES2062860T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPOSICIONES FARMACEUTICAS PARA LA MEJORA DE LA DISURIA QUE CONTIENEN UN PORTADOR FARMACEUTICO Y UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UN DERIVADO DE XANTINA REPRESENTADO POR LA FORMULA GENERAL I EN DONDE R1 REPRESENTA UN GRUPO DE LA FORMULA R4-CO PRESENTAN INDEPENDIENTEMENTE UN GRUPO ALQUILO QUE TIENE DE 1 A 3 ATOMOS DE CARBONO Y R6 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO QUE TIENE DE 1 A 3 ATOMOS DE CARBONO, R2 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO QUE TIENE DE 1 A 5 ATOMOS DE CARBONO O UN GRUPO ALQUILOXI QUE TIENE DE 1 A 5 ATOMOS DE CARBONO, R3 REPRESENTA UN GRUPO ALQUILO QUE TIENE DE 1 A 3 ATOMOS DE CARBONO Y N REPRESENTA DE 1 A 6 O UNA SAL DE ADICION ACIDA FARMACEUTICAMENTE ACEPTABLE DEL MISMO. SON ACTIVOS PARA PROLONGAR LOS INTERVALOS DE MICCION Y AUMENTAR LA PRESION UMBRAL DE MICCION SIN INFLUIR APENAS EN LA FUERZA CONSTRICTIVA DE LA VEJIGA. POR TANTO, SON EFECTIVAS PARA EL TRATAMIENTO Y PREVENCION DE LA DISURIA TAL COMO LA FRECUENCIA EXCESIVA DE MICCIONO LA INCONTINENCIA DE LA ORINA.
ES92121075T 1991-12-10 1992-12-10 Composicion farmaceutica para la mejoria de la disuria. Expired - Lifetime ES2062860T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3325458A JP2549480B2 (ja) 1991-12-10 1991-12-10 排尿障害改善剤

Publications (1)

Publication Number Publication Date
ES2062860T3 true ES2062860T3 (es) 1994-12-16

Family

ID=18177097

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92121075T Expired - Lifetime ES2062860T3 (es) 1991-12-10 1992-12-10 Composicion farmaceutica para la mejoria de la disuria.

Country Status (18)

Country Link
US (1) US5496823A (es)
EP (1) EP0546547B1 (es)
JP (1) JP2549480B2 (es)
KR (1) KR930012019A (es)
CN (1) CN1073861A (es)
AT (1) ATE110569T1 (es)
AU (1) AU656443B2 (es)
CA (1) CA2084962A1 (es)
CZ (1) CZ282422B6 (es)
DE (1) DE69200365T2 (es)
DK (1) DK0546547T3 (es)
ES (1) ES2062860T3 (es)
HU (2) HU9203911D0 (es)
IL (1) IL104026A (es)
MX (1) MX9207123A (es)
PH (1) PH30691A (es)
TW (1) TW210286B (es)
ZA (1) ZA929529B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780476A (en) * 1992-11-16 1998-07-14 Cell Therapeutics, Inc. Hydroxyl-containing xanthine compounds
DE19529102A1 (de) * 1995-08-08 1997-02-13 Kummer Horst Dieter Verwendung von PDE-Inhibitoren bei der Behandlung von Harnblasenerkrankungen
WO1998011888A1 (en) * 1996-09-19 1998-03-26 American Home Products Corporation Method of treating urinary incontinence
US20220054494A1 (en) * 2019-03-13 2022-02-24 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for treating bladder and urethra dysfunction and disease
WO2021065027A1 (ja) 2019-10-02 2021-04-08 あすか製薬株式会社 排尿障害改善剤
EP4039328A4 (en) 2019-10-02 2023-10-25 ASKA Pharmaceutical Co., Ltd. Dysuria-alleviating agent
TW202241452A (zh) 2020-12-18 2022-11-01 日商Ａｓｋａ製藥股份有限公司 固形製劑

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2330742C2 (de) * 1973-06-16 1982-07-29 Hoechst Ag, 6000 Frankfurt 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
JP2661666B2 (ja) * 1988-02-19 1997-10-08 ヘキスト薬品工業株式会社 抗消化性潰瘍剤

Also Published As

Publication number Publication date
DE69200365T2 (de) 1995-02-16
HUT63055A (en) 1993-07-28
ATE110569T1 (de) 1994-09-15
JPH05155773A (ja) 1993-06-22
CZ282422B6 (cs) 1997-07-16
HU9203911D0 (en) 1993-03-29
TW210286B (es) 1993-08-01
MX9207123A (es) 1993-07-30
KR930012019A (ko) 1993-07-20
CN1073861A (zh) 1993-07-07
CA2084962A1 (en) 1993-06-11
ZA929529B (en) 1993-06-15
IL104026A (en) 1995-11-27
AU656443B2 (en) 1995-02-02
IL104026A0 (en) 1993-05-13
DK0546547T3 (da) 1995-02-13
PH30691A (en) 1997-09-16
EP0546547B1 (en) 1994-08-31
JP2549480B2 (ja) 1996-10-30
AU2998592A (en) 1993-06-17
US5496823A (en) 1996-03-05
EP0546547A1 (en) 1993-06-16
CZ361192A3 (en) 1993-09-15
DE69200365D1 (de) 1994-10-06

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