ES2061819T3 - Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem. - Google Patents
Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem.Info
- Publication number
- ES2061819T3 ES2061819T3 ES89113136T ES89113136T ES2061819T3 ES 2061819 T3 ES2061819 T3 ES 2061819T3 ES 89113136 T ES89113136 T ES 89113136T ES 89113136 T ES89113136 T ES 89113136T ES 2061819 T3 ES2061819 T3 ES 2061819T3
- Authority
- ES
- Spain
- Prior art keywords
- synthesis
- intermediaries
- diltiazem
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
COMPUESTO DE FORMULA III, LA CUAL ES UN INTERMEDIO EN LA SINTESIS DE SOLUCIONES DE TIAZOL, SE PREPARA POR N-ALQUILACION DE LOS CORRESPONDIENTES DERIVADOS N-H CON 2-DIMETILAMINOETANOL EN UN DISOLVENTE INERTE Y EN PRESENCIA DE CLORURO DE METANOSULFONILO Y UNA BASE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8821479A IT1226301B (it) | 1988-07-26 | 1988-07-26 | Processo per la preparazione di intermedi per la sintesi del diltiazem. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2061819T3 true ES2061819T3 (es) | 1994-12-16 |
Family
ID=11182442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89113136T Expired - Lifetime ES2061819T3 (es) | 1988-07-26 | 1989-07-18 | Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4937334A (es) |
EP (1) | EP0355395B1 (es) |
JP (1) | JP3101819B2 (es) |
AT (1) | ATE103598T1 (es) |
DE (1) | DE68914211T2 (es) |
ES (1) | ES2061819T3 (es) |
IT (1) | IT1226301B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1244878B (it) * | 1990-12-11 | 1994-09-12 | Lusochimica Spa | Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato |
TW438787B (en) * | 1997-02-27 | 2001-06-07 | Tanabe Seiyaku Co | Process for preparing optically active trans-3-substituted glycidic acid ester |
FR3033701B1 (fr) | 2015-03-19 | 2021-01-15 | Univ Claude Bernard Lyon | Nouvelles compositions antivirales pour le traitement de la grippe |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
JPS5899471A (ja) * | 1981-12-07 | 1983-06-13 | Tanabe Seiyaku Co Ltd | ベンゾチアゼピン誘導体の新規製造法 |
US4567175A (en) * | 1983-06-03 | 1986-01-28 | Tanabe Seiyaku Co., Ltd. | 8-Chloro-1,5-benzothiazepine derivatives |
HU195795B (en) * | 1985-11-06 | 1988-07-28 | Richter Gedeon Vegyeszet | Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one |
-
1988
- 1988-07-26 IT IT8821479A patent/IT1226301B/it active
-
1989
- 1989-07-18 EP EP89113136A patent/EP0355395B1/en not_active Expired - Lifetime
- 1989-07-18 ES ES89113136T patent/ES2061819T3/es not_active Expired - Lifetime
- 1989-07-18 DE DE68914211T patent/DE68914211T2/de not_active Expired - Fee Related
- 1989-07-18 AT AT89113136T patent/ATE103598T1/de not_active IP Right Cessation
- 1989-07-25 US US07/384,730 patent/US4937334A/en not_active Expired - Lifetime
- 1989-07-26 JP JP01193818A patent/JP3101819B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IT1226301B (it) | 1990-12-27 |
JP3101819B2 (ja) | 2000-10-23 |
EP0355395B1 (en) | 1994-03-30 |
ATE103598T1 (de) | 1994-04-15 |
DE68914211T2 (de) | 1994-07-07 |
US4937334A (en) | 1990-06-26 |
EP0355395A1 (en) | 1990-02-28 |
IT8821479A0 (it) | 1988-07-26 |
DE68914211D1 (de) | 1994-05-05 |
JPH0278673A (ja) | 1990-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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