ES2060775T3 - Egf para la prevencion de daños en tejidos despues de un episodio isquemico. - Google Patents
Egf para la prevencion de daños en tejidos despues de un episodio isquemico.Info
- Publication number
- ES2060775T3 ES2060775T3 ES89307909T ES89307909T ES2060775T3 ES 2060775 T3 ES2060775 T3 ES 2060775T3 ES 89307909 T ES89307909 T ES 89307909T ES 89307909 T ES89307909 T ES 89307909T ES 2060775 T3 ES2060775 T3 ES 2060775T3
- Authority
- ES
- Spain
- Prior art keywords
- egf
- prevention
- tissue damage
- ischemic episode
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE PROPORCIONA UN METODO PARA EVITAR EL DETERIORO DE LOS TEJIDOS EN UN PACIENTE, DESPUES QUE EL TEJIDO HA SIDO PRIVADO DEL APORTE DE SANGRE QUE RESULTA EN ISQUEMIA. EL METODO CONSISTE EN ADMINISTRAR AL PACIENTE UN POLIPEPTIDO QUE TIENE ACTIVIDAD DE FACTOR DE CRECIMIENTO EPIDERMICO, O ACTIVIDAD DE FACTOR DE CRECIMIENTO DE FIBROBLASTO, ANTES O DESPUES DEL SUCESO ISQUEMICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/227,579 US5057494A (en) | 1988-08-03 | 1988-08-03 | Method for preventing tissue damage after an ischemic episode |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2060775T3 true ES2060775T3 (es) | 1994-12-01 |
Family
ID=22853654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89307909T Expired - Lifetime ES2060775T3 (es) | 1988-08-03 | 1989-08-03 | Egf para la prevencion de daños en tejidos despues de un episodio isquemico. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5057494A (es) |
EP (1) | EP0357240B1 (es) |
JP (1) | JP2921870B2 (es) |
AU (1) | AU623423B2 (es) |
CA (1) | CA1332351C (es) |
DE (1) | DE68911068T2 (es) |
ES (1) | ES2060775T3 (es) |
ZA (1) | ZA895910B (es) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2814529B2 (ja) * | 1989-03-16 | 1998-10-22 | 味の素株式会社 | 虚血性脳障害治療薬 |
US5370870A (en) * | 1989-10-06 | 1994-12-06 | Genentech, Inc. | Method for protection against reactive oxygen species |
US5200176A (en) * | 1989-10-06 | 1993-04-06 | Genentech, Inc. | Method for protection of ischemic tissues using tumor nerosis factor |
IT1240683B (it) * | 1990-04-26 | 1993-12-17 | Zambon Spa | Composizione farmaceutica contenente egf |
US5434135A (en) * | 1990-08-02 | 1995-07-18 | Indu Parikh | Growth factor compositions, preparation and use |
AU660630B2 (en) * | 1990-10-01 | 1995-07-06 | Brigham And Women's Hospital | Beta-carotene and vitamin E therapy for inhibition of major vascular events |
WO1992007578A1 (en) * | 1990-10-25 | 1992-05-14 | Genentech, Inc. | Use of protective agents against reactive oxygen species |
GR1002610B (el) * | 1991-01-02 | 1997-02-20 | Johnson & Johnson Consumer Products Inc. | Θεραπευτικες συνθεσεις πληγων που περιεχουν παραγοντα αναπτυξης ινοβλαστων και ασκορβικον οξυ. |
US5530109A (en) * | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
SE9101840L (sv) * | 1991-06-14 | 1992-12-15 | Kabi Pharmacia | Ny medicinsk anvaendning |
US5733871A (en) * | 1991-11-08 | 1998-03-31 | The General Hospital Corporation | Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration |
AU659723B2 (en) * | 1992-02-14 | 1995-05-25 | Kaken Pharmaceutical Co., Ltd. | Remedy for airway diseases |
CA2061567C (en) * | 1992-02-20 | 1998-02-03 | Rudolf E. Falk | Use of hyaluronic acid to repair ischemia reperfusion damage |
ES2061380B1 (es) * | 1992-11-23 | 1995-07-01 | Boehringer Ingelheim Espana | Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores. |
WO1994021116A1 (en) * | 1993-03-16 | 1994-09-29 | Alliance Pharmaceutical Corp. | Preservation solution and method for warm organ preservation |
AU7404994A (en) * | 1993-07-30 | 1995-02-28 | Regents Of The University Of California, The | Endocardial infusion catheter |
US5464815A (en) * | 1993-09-08 | 1995-11-07 | Genentech, Inc. | Inhibition of heparin-binding |
US5411940A (en) * | 1993-09-29 | 1995-05-02 | Alcon Laboratories, Inc. | Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma |
US5449671A (en) * | 1993-09-29 | 1995-09-12 | Alcon Laboratories, Inc. | Use of TGF-β3, to prevent or retard fistula closure following glaucoma filtration surgery |
JP3145409B2 (ja) | 1995-03-24 | 2001-03-12 | フォーカル, インコーポレイテッド | 活性酸素阻害剤の制御送達を用いる癒着の低減 |
US6214796B1 (en) | 1996-03-22 | 2001-04-10 | The General Hospital Corporation | Administration of polypeptide growth factors following central nervous system ischemia or trauma |
US20030113271A1 (en) * | 1997-01-29 | 2003-06-19 | University Technology Corporation | Formulations for pulmonary delivery |
US6306826B1 (en) * | 1997-06-04 | 2001-10-23 | The Regents Of The University Of California | Treatment of heart failure with growth hormone |
US6123956A (en) * | 1997-07-10 | 2000-09-26 | Keith Baker | Methods for universally distributing therapeutic agents to the brain |
US6191109B1 (en) * | 1997-10-31 | 2001-02-20 | Children's Hospital, Inc. | Methods of treating intestinal ischemia using heparin-binding epidermal growth factor |
US7304029B1 (en) * | 1998-09-03 | 2007-12-04 | Neuren Pharmaceuticals Ltd. | Neuroprotective effect of growth hormone |
US7112570B2 (en) | 2000-08-24 | 2006-09-26 | Neuren Pharmaceuticals, Ltd. | GPE analogs |
CN1466463A (zh) | 2000-09-13 | 2004-01-07 | 中外制药株式会社 | 缺血性疾病治疗剂 |
CU23157A1 (es) | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
US20040077689A1 (en) * | 2001-04-25 | 2004-04-22 | Yasuo Sugiyama | Abc expression promoters |
DE60232880D1 (de) | 2001-05-24 | 2009-08-20 | Neuren Pharmaceuticals Ltd | Gpe-analoga und peptidomimetika |
US7605177B2 (en) | 2001-05-24 | 2009-10-20 | Neuren Pharmaceuticals Limited | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration |
US7714020B2 (en) | 2001-05-24 | 2010-05-11 | Neuren Pharmaceuticals Limited | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate |
US7202066B2 (en) | 2002-01-29 | 2007-04-10 | Carrington Laboratories, Inc. | Combination of a growth factor and a protease enzyme |
US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
US7723327B2 (en) * | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
US7375133B2 (en) * | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
CA2495167C (en) * | 2002-07-29 | 2018-08-21 | Hawaii Biotech, Inc. | Structural carotenoid analogs for the inhibition and amelioration of disease |
US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
US7763649B2 (en) * | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
US20050009788A1 (en) * | 2002-07-29 | 2005-01-13 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling connexin 43 expression |
AU2003263948A1 (en) * | 2002-08-22 | 2004-03-11 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
US20040044220A1 (en) * | 2002-08-22 | 2004-03-04 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
WO2005102356A1 (en) * | 2004-04-14 | 2005-11-03 | Hawaii Biotech, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
US8093213B2 (en) * | 2007-04-30 | 2012-01-10 | Nationwide Children's Hospital, Inc. | Heparin binding epidermal growth factor (HB-EGF) for use in methods of treating and preventing intestinal injury related to hemorrhagic shock and resuscitation |
US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
US10702226B2 (en) | 2015-08-06 | 2020-07-07 | Covidien Lp | System and method for local three dimensional volume reconstruction using a standard fluoroscope |
US10674982B2 (en) | 2015-08-06 | 2020-06-09 | Covidien Lp | System and method for local three dimensional volume reconstruction using a standard fluoroscope |
US10716525B2 (en) | 2015-08-06 | 2020-07-21 | Covidien Lp | System and method for navigating to target and performing procedure on target utilizing fluoroscopic-based local three dimensional volume reconstruction |
US11529190B2 (en) | 2017-01-30 | 2022-12-20 | Covidien Lp | Enhanced ablation and visualization techniques for percutaneous surgical procedures |
US11793579B2 (en) | 2017-02-22 | 2023-10-24 | Covidien Lp | Integration of multiple data sources for localization and navigation |
US10699448B2 (en) | 2017-06-29 | 2020-06-30 | Covidien Lp | System and method for identifying, marking and navigating to a target using real time two dimensional fluoroscopic data |
EP3694412A4 (en) | 2017-10-10 | 2021-08-18 | Covidien LP | SYSTEM AND METHOD FOR IDENTIFYING AND MARKING A TARGET IN A THREE-DIMENSIONAL FLUOROSCOPIC RECONSTRUCTION |
US10893842B2 (en) | 2018-02-08 | 2021-01-19 | Covidien Lp | System and method for pose estimation of an imaging device and for determining the location of a medical device with respect to a target |
US11705238B2 (en) | 2018-07-26 | 2023-07-18 | Covidien Lp | Systems and methods for providing assistance during surgery |
US11877806B2 (en) | 2018-12-06 | 2024-01-23 | Covidien Lp | Deformable registration of computer-generated airway models to airway trees |
US11617493B2 (en) | 2018-12-13 | 2023-04-04 | Covidien Lp | Thoracic imaging, distance measuring, surgical awareness, and notification system and method |
US11801113B2 (en) | 2018-12-13 | 2023-10-31 | Covidien Lp | Thoracic imaging, distance measuring, and notification system and method |
US11357593B2 (en) | 2019-01-10 | 2022-06-14 | Covidien Lp | Endoscopic imaging with augmented parallax |
US11625825B2 (en) | 2019-01-30 | 2023-04-11 | Covidien Lp | Method for displaying tumor location within endoscopic images |
US11744643B2 (en) | 2019-02-04 | 2023-09-05 | Covidien Lp | Systems and methods facilitating pre-operative prediction of post-operative tissue function |
US11627924B2 (en) | 2019-09-24 | 2023-04-18 | Covidien Lp | Systems and methods for image-guided navigation of percutaneously-inserted devices |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE474981A (es) * | 1940-02-20 | |||
US4378347A (en) * | 1980-06-30 | 1983-03-29 | Franco Wayne P | Composition for treating the heart for myocardial infarction |
US4766073A (en) * | 1985-02-25 | 1988-08-23 | Zymogenetics Inc. | Expression of biologically active PDGF analogs in eucaryotic cells |
DE10120467A1 (de) * | 2001-04-26 | 2002-10-31 | Bosch Gmbh Robert | Wischblatt zum Reinigen von Scheiben, insbesondere von Kraftfahrzeugen |
-
1988
- 1988-08-03 US US07/227,579 patent/US5057494A/en not_active Expired - Lifetime
-
1989
- 1989-08-02 ZA ZA895910A patent/ZA895910B/xx unknown
- 1989-08-02 CA CA000607374A patent/CA1332351C/en not_active Expired - Fee Related
- 1989-08-02 AU AU39244/89A patent/AU623423B2/en not_active Ceased
- 1989-08-03 DE DE68911068T patent/DE68911068T2/de not_active Expired - Lifetime
- 1989-08-03 ES ES89307909T patent/ES2060775T3/es not_active Expired - Lifetime
- 1989-08-03 JP JP1202266A patent/JP2921870B2/ja not_active Expired - Fee Related
- 1989-08-03 EP EP89307909A patent/EP0357240B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2921870B2 (ja) | 1999-07-19 |
CA1332351C (en) | 1994-10-11 |
AU623423B2 (en) | 1992-05-14 |
EP0357240A2 (en) | 1990-03-07 |
EP0357240A3 (en) | 1991-07-24 |
ZA895910B (en) | 1991-04-24 |
EP0357240B1 (en) | 1993-12-01 |
JPH0283334A (ja) | 1990-03-23 |
US5057494A (en) | 1991-10-15 |
AU3924489A (en) | 1990-02-08 |
DE68911068T2 (de) | 1994-06-30 |
DE68911068D1 (de) | 1994-01-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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