ES2059710T3 - Granulados para composiciones orales de particulas multiples del tipo de liberacion controlada. - Google Patents
Granulados para composiciones orales de particulas multiples del tipo de liberacion controlada.Info
- Publication number
- ES2059710T3 ES2059710T3 ES89203243T ES89203243T ES2059710T3 ES 2059710 T3 ES2059710 T3 ES 2059710T3 ES 89203243 T ES89203243 T ES 89203243T ES 89203243 T ES89203243 T ES 89203243T ES 2059710 T3 ES2059710 T3 ES 2059710T3
- Authority
- ES
- Spain
- Prior art keywords
- granulates
- controlled release
- oral compositions
- release type
- multiple particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
GRANULADOS PARA COMPOSICIONES ORALES DE LIBERACION CONTROLADA MULTIPARTICULADA QUE COMPRENDEN SUSTANCIAS ACTIVAS BIOLOGICAMENTE EN LA DISPERSION SOLIDA CON UN COMPONENTE LIMITADOR DE LIBERACION Y/O RESISTENTE DE ACIDO, LA DISPERSION SOLIDA ES MEZCLADA CON PARTICULAS PORTADORAS INSOLUBLES EN AGUA, Y LA PREPARACION DE TALES GRANULADOS. LAS SUSTANCIAS ACTIVAS BIOLOGICAMENTE REFERIDAS SON CORTICOESTEROIDES, NO DROGAS ANTI-INFLAMATORIAS NO ESTEROIDALES Y COMPONENTES DE BISMUTO. LOS GRANULOS TIENEN UN TAMAÑO DE PARTICULA REFERIDO DE MENOS QUE 1 MM.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88202983 | 1988-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2059710T3 true ES2059710T3 (es) | 1994-11-16 |
Family
ID=8199893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89203243T Expired - Lifetime ES2059710T3 (es) | 1988-12-20 | 1989-12-18 | Granulados para composiciones orales de particulas multiples del tipo de liberacion controlada. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0375063B1 (es) |
JP (1) | JPH02223513A (es) |
KR (1) | KR900009059A (es) |
CN (1) | CN1044398A (es) |
AU (1) | AU622745B2 (es) |
CA (1) | CA2005992A1 (es) |
DE (1) | DE68909023T2 (es) |
DK (1) | DK647689A (es) |
ES (1) | ES2059710T3 (es) |
FI (1) | FI896062A0 (es) |
HU (1) | HU203279B (es) |
IL (1) | IL92343A0 (es) |
NO (1) | NO176125C (es) |
NZ (1) | NZ231828A (es) |
PT (1) | PT92616B (es) |
ZA (1) | ZA899732B (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776493A (en) * | 1989-07-14 | 1998-07-07 | Alza Corporation | Oral osmotic device for delivery of nystatin with hydrogel driving member |
GEP19971086B (en) * | 1991-02-22 | 1997-12-02 | Tillotts Pharma Ag | Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine |
TW212139B (es) * | 1991-04-15 | 1993-09-01 | Yamanouchi Pharma Co Ltd | |
WO1992018106A1 (en) * | 1991-04-16 | 1992-10-29 | Nippon Shinyaku Co., Ltd. | Method of manufacturing solid dispersion |
US5248310A (en) * | 1992-03-27 | 1993-09-28 | Alza Corporation | Oral osmotic device with hydrogel driving member |
US5512299A (en) * | 1992-03-30 | 1996-04-30 | Alza Corporation | Method of treating oral inflammatory disease |
WO1995016451A1 (fr) * | 1992-06-22 | 1995-06-22 | Franck Arno Gouchet | Comprimes a liberation controlee de 4-asa |
FR2692484B1 (fr) * | 1992-06-22 | 1995-06-30 | Gouchet Franck | Nouvelle forme galenique de 4-asa a liberation controlee. |
US5395627A (en) * | 1992-09-04 | 1995-03-07 | Akzo N.V. | Pharmaceutical granulate |
US5573776A (en) * | 1992-12-02 | 1996-11-12 | Alza Corporation | Oral osmotic device with hydrogel driving member |
US6426085B1 (en) | 1994-05-02 | 2002-07-30 | Josman Laboratories Inc. | Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis |
US5834002A (en) | 1994-05-02 | 1998-11-10 | Josman Laboratories, Inc. | Chewing gum containing colloidal bismuth subcitrate |
US6902738B2 (en) | 1994-05-02 | 2005-06-07 | Josman Laboratories, Inc. | Topical oral dosage forms containing bismuth compounds |
AT403988B (de) * | 1994-05-18 | 1998-07-27 | Lannacher Heilmittel | Festes orales retardpräparat |
GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
US6379651B1 (en) | 1995-02-07 | 2002-04-30 | Josman Laboratories | Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases |
US6372784B1 (en) | 1995-02-07 | 2002-04-16 | Josman Laboratories, Inc. | Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds |
IT1301947B1 (it) * | 1998-07-28 | 2000-07-20 | Chiesi Farma Spa | Formulazioni farmaceutiche di beclometasone dipropionato per iltrattamento di malattie infiammatorie croniche della mucosa |
DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
ITMI991316A1 (it) * | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
PT1183014E (pt) | 1999-06-14 | 2003-12-31 | Cosmo Spa | Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor |
US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
JP4310605B2 (ja) * | 2001-05-25 | 2009-08-12 | 大塚製薬株式会社 | 医薬用組成物 |
US20030190343A1 (en) * | 2002-03-05 | 2003-10-09 | Pfizer Inc. | Palatable pharmaceutical compositions for companion animals |
US8557291B2 (en) | 2002-07-05 | 2013-10-15 | Collegium Pharmaceutical, Inc. | Abuse-deterrent pharmaceutical compositions of opioids and other drugs |
AU2003247876B2 (en) | 2002-07-05 | 2006-10-05 | Collegium Pharmaceutical, Inc | Abuse-deterrent pharmaceutical compositions of opiods and other drugs |
US10004729B2 (en) | 2002-07-05 | 2018-06-26 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US8840928B2 (en) | 2002-07-05 | 2014-09-23 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
WO2005123039A1 (en) | 2004-06-12 | 2005-12-29 | Collegium Pharmaceutical, Inc. | Abuse-deterrent drug formulations |
US20070048373A1 (en) * | 2005-08-30 | 2007-03-01 | Cima Labs Inc. | Dried milled granulate and methods |
US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
EP2538923A2 (en) * | 2010-02-22 | 2013-01-02 | Lupin Limited | Taste-masked powder for suspension compositions of methylprednisolone |
IT1405012B1 (it) * | 2010-08-06 | 2013-12-16 | Sofar Spa | Composizioni di beclometasone dipropionato in microsfere gastroresistenti a rilascio modificato e processo per il loro ottenimento |
US10154964B2 (en) | 2011-09-07 | 2018-12-18 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
WO2017222575A1 (en) | 2016-06-23 | 2017-12-28 | Collegium Pharmaceutical, Inc. | Process of making more stable abuse-deterrent oral formulations |
-
1989
- 1989-11-17 IL IL92343A patent/IL92343A0/xx not_active IP Right Cessation
- 1989-12-12 KR KR1019890018375A patent/KR900009059A/ko not_active Application Discontinuation
- 1989-12-18 DE DE89203243T patent/DE68909023T2/de not_active Expired - Fee Related
- 1989-12-18 FI FI896062A patent/FI896062A0/fi not_active IP Right Cessation
- 1989-12-18 NZ NZ231828A patent/NZ231828A/en unknown
- 1989-12-18 ES ES89203243T patent/ES2059710T3/es not_active Expired - Lifetime
- 1989-12-18 EP EP89203243A patent/EP0375063B1/en not_active Expired - Lifetime
- 1989-12-19 ZA ZA899732A patent/ZA899732B/xx unknown
- 1989-12-19 CN CN89109394A patent/CN1044398A/zh active Pending
- 1989-12-19 DK DK647689A patent/DK647689A/da not_active Application Discontinuation
- 1989-12-19 CA CA002005992A patent/CA2005992A1/en not_active Abandoned
- 1989-12-19 HU HU896686A patent/HU203279B/hu not_active IP Right Cessation
- 1989-12-19 PT PT92616A patent/PT92616B/pt not_active IP Right Cessation
- 1989-12-19 JP JP1329380A patent/JPH02223513A/ja active Pending
- 1989-12-19 NO NO895114A patent/NO176125C/no unknown
- 1989-12-20 AU AU47131/89A patent/AU622745B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0375063A1 (en) | 1990-06-27 |
NO176125C (no) | 1995-02-08 |
NO176125B (no) | 1994-10-31 |
DK647689D0 (da) | 1989-12-19 |
EP0375063B1 (en) | 1993-09-08 |
PT92616B (pt) | 1995-09-12 |
CA2005992A1 (en) | 1990-06-20 |
PT92616A (pt) | 1990-06-29 |
DE68909023T2 (de) | 1994-02-03 |
AU622745B2 (en) | 1992-04-16 |
IL92343A0 (en) | 1990-07-26 |
NO895114L (no) | 1990-06-21 |
HU896686D0 (en) | 1990-02-28 |
AU4713189A (en) | 1990-06-28 |
KR900009059A (ko) | 1990-07-02 |
HUT53514A (en) | 1990-11-28 |
NZ231828A (en) | 1992-03-26 |
FI896062A0 (fi) | 1989-12-18 |
DE68909023D1 (de) | 1993-10-14 |
JPH02223513A (ja) | 1990-09-05 |
CN1044398A (zh) | 1990-08-08 |
NO895114D0 (no) | 1989-12-19 |
ZA899732B (en) | 1990-09-26 |
DK647689A (da) | 1990-06-21 |
HU203279B (en) | 1991-07-29 |
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