ES2059513T3 - Un procedimiento para la preparacion de un derivado cinamoilamida. - Google Patents
Un procedimiento para la preparacion de un derivado cinamoilamida.Info
- Publication number
- ES2059513T3 ES2059513T3 ES88304121T ES88304121T ES2059513T3 ES 2059513 T3 ES2059513 T3 ES 2059513T3 ES 88304121 T ES88304121 T ES 88304121T ES 88304121 T ES88304121 T ES 88304121T ES 2059513 T3 ES2059513 T3 ES 2059513T3
- Authority
- ES
- Spain
- Prior art keywords
- chain
- hydrogen atom
- derivative
- group
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/29—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Abstract
UN DERIVADO DE CIANOMOILAMIDA DE FORMULA (I) DONDE (I) R1, R2 Y R3 PUEDEN SER LOS MISMOS O DIFERENTES Y REPRESENTAN UN ATOMO DE HALOGENO, UN GRUPO ALCOXI DE CADENA RECTA O RAMOFICADA DE 1 A 7 ATOMOS DE C, UN GRUPO ALQUILO DE CADENA RECTA O RAMIFICADA DE 1 A 7 ATOMOS DE C O UN GRUPO NITRO Y DE R4 Y R5 REPRESENTA UN GRUPO METILO Y EL OTRO REPRESENTA UN ATOMO DE HIDROGENO O (II) UNO DE R1, R2 Y R3 REPRESENTAN 4-ISOBUTILO, 4-BUTILO, 4-PROPILO, 4-BUTOXI O 4-SEC-BUTILO Y LOS OTROS DOS REPRESENTAN UN ATOMO DE HIDROGENO, R4 REPRESENTA UN GRUPO METILO Y R5 REPRESENTA UN ATOMO DE HIDROGENO, Y SUS SALES NO TOXICAS POSEEN ACTIVIDAD INHIBITORIA SOBRE 5ALFA-REDUCTASA, INDICADORA DE UTILIDAD PARA TRATAR Y/O PREVENIR ALOPECIA, ACNE O HIPERTROFIA PROSTATICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14153387 | 1987-06-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2059513T3 true ES2059513T3 (es) | 1994-11-16 |
Family
ID=15294182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88304121T Expired - Lifetime ES2059513T3 (es) | 1987-06-08 | 1988-05-06 | Un procedimiento para la preparacion de un derivado cinamoilamida. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4863963A (es) |
EP (1) | EP0294937B1 (es) |
JP (1) | JPH0730001B2 (es) |
KR (1) | KR970006473B1 (es) |
AT (1) | ATE92468T1 (es) |
DE (1) | DE3882816T2 (es) |
ES (1) | ES2059513T3 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5191113A (en) * | 1987-05-07 | 1993-03-02 | Ono Pharmaceutical Co., Ltd. | Cinnamoylamide derivatives |
US5239083A (en) * | 1991-03-11 | 1993-08-24 | Kyowa Hakko Kogyo Co., Ltd. | Indole derivatives which inhibit steroid 5α reductase |
EP0641211A1 (en) * | 1992-05-21 | 1995-03-08 | Endorecherche Inc. | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY |
US6013764A (en) * | 1996-07-17 | 2000-01-11 | Ortho Pharmaceutical Corp. | Liquid phase peptide synthesis of KL-4 pulmonary surfactant |
US6555095B1 (en) | 2001-12-14 | 2003-04-29 | Avon Products, Inc. | Topical compositions and methods of application |
US6517816B1 (en) | 2001-12-26 | 2003-02-11 | Avon Products, Inc. | Sunscreen emulsion composition and method of use |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2164481A1 (en) * | 1971-12-21 | 1973-08-03 | Aries Robert | Phenylacylamino phenylalkanoic acids - antiinflammatories antipyretics analgesics and antirheumatics |
GB1484413A (en) * | 1974-04-18 | 1977-09-01 | Kissei Pharmaceutical | Aromatic amidocarboxylic acid derivatives |
DE2541342A1 (de) * | 1975-09-17 | 1977-03-31 | Boehringer Mannheim Gmbh | Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben |
JPS5838244A (ja) * | 1981-09-01 | 1983-03-05 | Kissei Pharmaceut Co Ltd | 核置換シンナモイルアントラニル酸塩およびその製造方法 |
US4536346A (en) * | 1983-05-06 | 1985-08-20 | American Cyanamid Company | Aralkanamidophenyl compounds |
CA1261835A (en) * | 1984-08-20 | 1989-09-26 | Masaaki Toda | (fused) benz(thio)amides |
JPS62198653A (ja) * | 1986-02-27 | 1987-09-02 | Ono Pharmaceut Co Ltd | 2−アミノフエノキシ(チオ)アルキルカルボニルアミノ酸誘導体、それらの製造方法およびそれらの化合物を有効成分として含有する5α−リダクタ−ゼ阻害剤 |
-
1988
- 1988-05-05 KR KR1019880005229A patent/KR970006473B1/ko active IP Right Grant
- 1988-05-06 US US07/191,195 patent/US4863963A/en not_active Expired - Fee Related
- 1988-05-06 EP EP88304121A patent/EP0294937B1/en not_active Expired - Lifetime
- 1988-05-06 DE DE88304121T patent/DE3882816T2/de not_active Expired - Fee Related
- 1988-05-06 AT AT88304121T patent/ATE92468T1/de not_active IP Right Cessation
- 1988-05-06 ES ES88304121T patent/ES2059513T3/es not_active Expired - Lifetime
- 1988-06-08 JP JP13946288A patent/JPH0730001B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR890000406A (ko) | 1989-03-14 |
EP0294937A2 (en) | 1988-12-14 |
KR970006473B1 (ko) | 1997-04-28 |
US4863963A (en) | 1989-09-05 |
JPS6485954A (en) | 1989-03-30 |
JPH0730001B2 (ja) | 1995-04-05 |
DE3882816T2 (de) | 1993-12-09 |
EP0294937B1 (en) | 1993-08-04 |
EP0294937A3 (en) | 1989-10-18 |
ATE92468T1 (de) | 1993-08-15 |
DE3882816D1 (de) | 1993-09-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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