ES2057777T3 - Composicion farmaceutica para inhibir la agregacion plaquetaria. - Google Patents

Composicion farmaceutica para inhibir la agregacion plaquetaria.

Info

Publication number
ES2057777T3
ES2057777T3 ES91307773T ES91307773T ES2057777T3 ES 2057777 T3 ES2057777 T3 ES 2057777T3 ES 91307773 T ES91307773 T ES 91307773T ES 91307773 T ES91307773 T ES 91307773T ES 2057777 T3 ES2057777 T3 ES 2057777T3
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
alkyl group
platelet aggregation
lower alkyl
inhibit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91307773T
Other languages
English (en)
Inventor
Akio Odawara
Yasuhiko Sasaki
Sakae Murata
Hiroshi Narita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2243729A external-priority patent/JPH078799B2/ja
Priority claimed from JP2243728A external-priority patent/JPH078798B2/ja
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of ES2057777T3 publication Critical patent/ES2057777T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UNA COMPOSICION FARMACEUTICA PARA INHIBIR LA AGREGACION DE PLAQUETAS QUE COMPRENDE UN ACIDO ACETILSALICILICO O UNA SAL DE LO ANTERIOR FARMACEUTICAMENTE ACEPTABLE Y UN DERIVADO DEL 1,5-BENZOTIAZEPINA DE FORMULA: DONDE R ELEVADO 1 ES UN GRUPO DE ALQUILO BAJO O UN GRUPO DE ALCOXI BAJO, R (AL CUADRADO) ES UN ATOMO DE HIDROGENO O UN ALCANOIL BAJO, R ELEVADO 3 ES UN GRUPO ALQUILO BAJO, R ELEVADO 4 ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO BAJO Y R ELEVADO 5 ES UN GRUPO ALQUILO BAJO O UN ATOMO DE HALOGENO O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LO ANTERIOR.
ES91307773T 1990-09-17 1991-08-23 Composicion farmaceutica para inhibir la agregacion plaquetaria. Expired - Lifetime ES2057777T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2243729A JPH078799B2 (ja) 1990-09-17 1990-09-17 血小板凝集抑制組成物
JP2243728A JPH078798B2 (ja) 1990-09-17 1990-09-17 血小板凝集抑制組成物

Publications (1)

Publication Number Publication Date
ES2057777T3 true ES2057777T3 (es) 1994-10-16

Family

ID=26536403

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91307773T Expired - Lifetime ES2057777T3 (es) 1990-09-17 1991-08-23 Composicion farmaceutica para inhibir la agregacion plaquetaria.

Country Status (9)

Country Link
US (1) US5387581A (es)
EP (1) EP0476854B1 (es)
KR (1) KR0145689B1 (es)
AT (1) ATE106734T1 (es)
CA (1) CA2049655C (es)
DE (1) DE69102379T2 (es)
DK (1) DK0476854T3 (es)
ES (1) ES2057777T3 (es)
FR (1) FR2666741B1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0595526B1 (en) * 1992-10-23 1997-09-10 Tanabe Seiyaku Co., Ltd. Peripheral circulation improving agent
US5637582A (en) * 1992-10-23 1997-06-10 Tanabe Seiyaku Co., Ltd. Peripheral circulation improving agent
MA24512A1 (fr) * 1996-01-17 1998-12-31 Univ Vermont And State Agrienl Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
US20070190059A1 (en) * 1996-01-17 2007-08-16 Smithkline Beecham Corporation Antithrombotic agents
US20030235587A1 (en) * 1998-08-07 2003-12-25 Feuerstein Giora Z. Anticoagulant agents useful in treatment of thrombosis
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
WO2001087339A1 (en) * 2000-05-15 2001-11-22 Smithkline Beecham Corporation Antithrombotic agents
ATE532058T1 (de) 2004-05-17 2011-11-15 Medtronic Inc Point-of-care-heparinbestimmungssystem

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4590188A (en) * 1984-02-18 1986-05-20 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and their pharmaceutical use
US4594342A (en) * 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative
FR2589358B1 (fr) * 1985-07-30 1987-12-04 Synthelabo Compositions pharmaceutiques a base de diltiazem et d'aspirine
DE3626097A1 (de) * 1986-07-31 1988-02-11 Goedecke Ag Wirkstoffkombination enthaltend diltiazem und acetylsalicylsaeure

Also Published As

Publication number Publication date
DK0476854T3 (da) 1994-07-11
DE69102379D1 (de) 1994-07-14
EP0476854A1 (en) 1992-03-25
ATE106734T1 (de) 1994-06-15
US5387581A (en) 1995-02-07
FR2666741B1 (fr) 1993-01-08
FR2666741A1 (fr) 1992-03-20
EP0476854B1 (en) 1994-06-08
CA2049655A1 (en) 1992-03-18
KR0145689B1 (ko) 1998-08-17
CA2049655C (en) 1996-11-12
KR920005986A (ko) 1992-04-27
DE69102379T2 (de) 1994-09-29

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