ES2056832T5 - Vehiculo para la liberacion que contiene un agente activo asociado con una substancia anfifila. - Google Patents
Vehiculo para la liberacion que contiene un agente activo asociado con una substancia anfifila.Info
- Publication number
- ES2056832T5 ES2056832T5 ES87311040T ES87311040T ES2056832T5 ES 2056832 T5 ES2056832 T5 ES 2056832T5 ES 87311040 T ES87311040 T ES 87311040T ES 87311040 T ES87311040 T ES 87311040T ES 2056832 T5 ES2056832 T5 ES 2056832T5
- Authority
- ES
- Spain
- Prior art keywords
- amphifila
- substance
- active agent
- vehicle containing
- agent associated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
- H02M1/00—Details of apparatus for conversion
- H02M1/08—Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
- H02M1/00—Details of apparatus for conversion
- H02M1/06—Circuits specially adapted for rendering non-conductive gas discharge tubes or equivalent semiconductor devices, e.g. thyratrons, thyristors
Abstract
SE DESCRIBEN VEHICULOS DE LIBERACION QUE COMPRENDEN UNA CAPA ENCAPSULANTE BIOCOMPATIBLE, UNA CAPA ASOCIADA A UN PRINCIPIO ACTIVO ANFIFILICO INTERNA Y UN PRINCIPIO ACTIVO. LOS VEHICULOS DE LIBERACION SON BIOCOMPATIBLES Y CAPACES DE SOLUBILIZAR EL PRINCIPIO PARA LIBERACION EN VIVO A TEJIDOS Y OTROS SISTEMAS CORPOREOS. LOS USOS INCLUYEN FORMACION DE IMAGEN EN RMN Y COMO MEDICAMENTO TERAPEUTICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94209386A | 1986-12-15 | 1986-12-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2056832T3 ES2056832T3 (es) | 1994-10-16 |
ES2056832T5 true ES2056832T5 (es) | 1999-04-16 |
Family
ID=25477566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87311040T Expired - Lifetime ES2056832T5 (es) | 1986-12-15 | 1987-12-15 | Vehiculo para la liberacion que contiene un agente activo asociado con una substancia anfifila. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0272091B2 (es) |
JP (1) | JP2677572B2 (es) |
KR (2) | KR950015052B1 (es) |
AT (1) | ATE89717T1 (es) |
AU (1) | AU608264B2 (es) |
CA (1) | CA1319614C (es) |
DE (1) | DE3786005T3 (es) |
DK (1) | DK175531B1 (es) |
ES (1) | ES2056832T5 (es) |
IE (1) | IE60562B1 (es) |
NO (1) | NO171583C (es) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043107A (en) * | 1986-08-21 | 1991-08-27 | Vestar Research, Inc. | Preparation small unilamellar vesicles including polyene antifungal antibiotics |
AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
JPH04501723A (ja) * | 1988-11-09 | 1992-03-26 | アンガー,エヴァン,シー. | リポソーム性放射線造影剤 |
US5580575A (en) | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
US5585112A (en) | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
US5773024A (en) | 1989-12-22 | 1998-06-30 | Imarx Pharmaceutical Corp. | Container with multi-phase composition for use in diagnostic and therapeutic applications |
US5088499A (en) * | 1989-12-22 | 1992-02-18 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5733572A (en) | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
US5776429A (en) | 1989-12-22 | 1998-07-07 | Imarx Pharmaceutical Corp. | Method of preparing gas-filled microspheres using a lyophilized lipids |
US5334381A (en) * | 1989-12-22 | 1994-08-02 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5352435A (en) * | 1989-12-22 | 1994-10-04 | Unger Evan C | Ionophore containing liposomes for ultrasound imaging |
US6146657A (en) | 1989-12-22 | 2000-11-14 | Imarx Pharmaceutical Corp. | Gas-filled lipid spheres for use in diagnostic and therapeutic applications |
US5656211A (en) | 1989-12-22 | 1997-08-12 | Imarx Pharmaceutical Corp. | Apparatus and method for making gas-filled vesicles of optimal size |
US6088613A (en) | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
US5305757A (en) | 1989-12-22 | 1994-04-26 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
US5922304A (en) | 1989-12-22 | 1999-07-13 | Imarx Pharmaceutical Corp. | Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents |
US6551576B1 (en) | 1989-12-22 | 2003-04-22 | Bristol-Myers Squibb Medical Imaging, Inc. | Container with multi-phase composition for use in diagnostic and therapeutic applications |
US6001335A (en) | 1989-12-22 | 1999-12-14 | Imarx Pharmaceutical Corp. | Contrasting agents for ultrasonic imaging and methods for preparing the same |
US5469854A (en) | 1989-12-22 | 1995-11-28 | Imarx Pharmaceutical Corp. | Methods of preparing gas-filled liposomes |
US5705187A (en) | 1989-12-22 | 1998-01-06 | Imarx Pharmaceutical Corp. | Compositions of lipids and stabilizing materials |
US5542935A (en) * | 1989-12-22 | 1996-08-06 | Imarx Pharmaceutical Corp. | Therapeutic delivery systems related applications |
US5091188A (en) * | 1990-04-26 | 1992-02-25 | Haynes Duncan H | Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs |
US5246707A (en) * | 1990-04-26 | 1993-09-21 | Haynes Duncan H | Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes |
US5215680A (en) * | 1990-07-10 | 1993-06-01 | Cavitation-Control Technology, Inc. | Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles |
CA2093665A1 (en) * | 1990-10-09 | 1992-04-10 | Sean M. Sullivan | Phospholipid analogue vesicle |
US5205290A (en) | 1991-04-05 | 1993-04-27 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
US5874062A (en) | 1991-04-05 | 1999-02-23 | Imarx Pharmaceutical Corp. | Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents |
US5464696A (en) * | 1992-08-13 | 1995-11-07 | Bracco International B.V. | Particles for NMR imaging |
WO1994026253A1 (en) * | 1993-05-19 | 1994-11-24 | The Liposome Company, Inc. | Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer |
US5411730A (en) * | 1993-07-20 | 1995-05-02 | Research Corporation Technologies, Inc. | Magnetic microparticles |
US5736121A (en) | 1994-05-23 | 1998-04-07 | Imarx Pharmaceutical Corp. | Stabilized homogenous suspensions as computed tomography contrast agents |
US5630786A (en) * | 1994-06-27 | 1997-05-20 | Ionix Corporation | Boron neutron capture enhancement of fast neutron therapy |
US6743779B1 (en) | 1994-11-29 | 2004-06-01 | Imarx Pharmaceutical Corp. | Methods for delivering compounds into a cell |
DE19500665A1 (de) * | 1995-01-12 | 1996-07-18 | Axel Prof Dr Haase | Verfahren zur ortsauflösenden Abbildung eines Bereiches eines biologischen Objektes mit Hilfe elektromagnetischer Strahlen unter Applikation von Kontrastmittel |
US5830430A (en) | 1995-02-21 | 1998-11-03 | Imarx Pharmaceutical Corp. | Cationic lipids and the use thereof |
US5997898A (en) | 1995-06-06 | 1999-12-07 | Imarx Pharmaceutical Corp. | Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery |
US6231834B1 (en) | 1995-06-07 | 2001-05-15 | Imarx Pharmaceutical Corp. | Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same |
US6521211B1 (en) | 1995-06-07 | 2003-02-18 | Bristol-Myers Squibb Medical Imaging, Inc. | Methods of imaging and treatment with targeted compositions |
US6033645A (en) | 1996-06-19 | 2000-03-07 | Unger; Evan C. | Methods for diagnostic imaging by regulating the administration rate of a contrast agent |
US6139819A (en) | 1995-06-07 | 2000-10-31 | Imarx Pharmaceutical Corp. | Targeted contrast agents for diagnostic and therapeutic use |
JP5038552B2 (ja) | 1995-10-17 | 2012-10-03 | オバン・エナジー・リミテッド | 不溶性薬物の送達 |
ATE345682T1 (de) | 1996-05-01 | 2006-12-15 | Imarx Pharmaceutical Corp | In vitro verfahren zum einbringen von nukleinsäuren in eine zelle |
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
US6414139B1 (en) | 1996-09-03 | 2002-07-02 | Imarx Therapeutics, Inc. | Silicon amphiphilic compounds and the use thereof |
US5846517A (en) | 1996-09-11 | 1998-12-08 | Imarx Pharmaceutical Corp. | Methods for diagnostic imaging using a renal contrast agent and a vasodilator |
ES2289188T3 (es) | 1996-09-11 | 2008-02-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Procedimiento para la obtencion de imagenes para el diagnostico usando un agente de contraste y un vasodilatador. |
FR2754828B1 (fr) * | 1996-10-23 | 1998-12-24 | Univ Toulouse | Structure membranaire artificielle, procede et polymere pour sa preparation, procede de preparation de ce polymere, particule et film comprenant cette structure |
US6143276A (en) | 1997-03-21 | 2000-11-07 | Imarx Pharmaceutical Corp. | Methods for delivering bioactive agents to regions of elevated temperatures |
US6537246B1 (en) | 1997-06-18 | 2003-03-25 | Imarx Therapeutics, Inc. | Oxygen delivery agents and uses for the same |
US6120751A (en) | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
US6090800A (en) | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
US6416740B1 (en) | 1997-05-13 | 2002-07-09 | Bristol-Myers Squibb Medical Imaging, Inc. | Acoustically active drug delivery systems |
US6548047B1 (en) | 1997-09-15 | 2003-04-15 | Bristol-Myers Squibb Medical Imaging, Inc. | Thermal preactivation of gaseous precursor filled compositions |
US6123923A (en) | 1997-12-18 | 2000-09-26 | Imarx Pharmaceutical Corp. | Optoacoustic contrast agents and methods for their use |
US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
AU764001B2 (en) | 1998-05-29 | 2003-08-07 | Skyepharma Canada Inc. | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
JP4809533B2 (ja) | 1998-11-20 | 2011-11-09 | オバン・エナジー・リミテッド | 分散し得るリン脂質で安定化されたミクロ粒子 |
JP5102423B2 (ja) | 2000-04-20 | 2012-12-19 | オバン・エナジー・リミテッド | 改善された水不溶性薬剤粒子の処理 |
ATE424811T1 (de) | 2000-08-31 | 2009-03-15 | Jagotec Ag | Gemahlene partikel |
DE10331439B3 (de) | 2003-07-10 | 2005-02-03 | Micromod Partikeltechnologie Gmbh | Magnetische Nanopartikel mit verbesserten Magneteigenschaften |
WO2006028129A1 (ja) * | 2004-09-10 | 2006-03-16 | Toray Industries, Inc. | 医薬品製剤 |
BRPI0721148B8 (pt) | 2006-12-18 | 2021-05-25 | Colorobbia Italiana Spa | nanopartículas magnéticas para aplicação em hipertermia, preparação destas e uso de construtos apresentando aplicação farmacológica |
JP5959118B2 (ja) * | 2011-06-13 | 2016-08-02 | 国立大学法人 千葉大学 | 医療用組織マーカー及びその製造方法 |
JP6482604B2 (ja) * | 2017-06-22 | 2019-03-13 | 教裕 南郷 | 外皮内溶解型ニードル及びニードル装置 |
CN110455848B (zh) * | 2018-05-08 | 2024-02-23 | 国家纳米科学中心 | 基于络合反应放大信号的铁离子纵向弛豫时间传感器及其构建方法、用途 |
EP3714879A1 (en) * | 2019-03-28 | 2020-09-30 | Sisaf Ltd | Structured encapsulated silicon-containing particles |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4208294A (en) * | 1979-02-12 | 1980-06-17 | The United States Of America, As Represented By The Secretary Of The Interior | Dilution stable water based magnetic fluids |
PT81498B (pt) * | 1984-11-23 | 1987-12-30 | Schering Ag | Processo para a preparacao de composicoes para diagnostico contendo particulas magneticas |
EP0198765A3 (en) * | 1985-04-09 | 1987-10-21 | Georgetown University | Preparation of liposomes |
US5041581A (en) * | 1985-10-18 | 1991-08-20 | The University Of Texas System Board Of Regents | Hydrophobic cis-platinum complexes efficiently incorporated into liposomes |
-
1987
- 1987-12-11 DK DK198706511A patent/DK175531B1/da not_active IP Right Cessation
- 1987-12-14 NO NO875194A patent/NO171583C/no not_active IP Right Cessation
- 1987-12-14 IE IE338787A patent/IE60562B1/en not_active IP Right Cessation
- 1987-12-14 CA CA000554194A patent/CA1319614C/en not_active Expired - Lifetime
- 1987-12-14 AU AU82494/87A patent/AU608264B2/en not_active Expired
- 1987-12-15 JP JP62317282A patent/JP2677572B2/ja not_active Expired - Lifetime
- 1987-12-15 ES ES87311040T patent/ES2056832T5/es not_active Expired - Lifetime
- 1987-12-15 EP EP87311040A patent/EP0272091B2/en not_active Expired - Lifetime
- 1987-12-15 KR KR1019870014304A patent/KR950015052B1/ko not_active IP Right Cessation
- 1987-12-15 DE DE3786005T patent/DE3786005T3/de not_active Expired - Lifetime
- 1987-12-15 AT AT87311040T patent/ATE89717T1/de not_active IP Right Cessation
- 1987-12-15 KR KR870014301A patent/KR880008502A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR880008502A (ko) | 1988-08-31 |
ATE89717T1 (de) | 1993-06-15 |
KR950015052B1 (ko) | 1995-12-21 |
KR880007065A (ko) | 1988-08-26 |
DK175531B1 (da) | 2004-11-22 |
CA1319614C (en) | 1993-06-29 |
DE3786005T3 (de) | 1999-04-01 |
IE60562B1 (en) | 1994-07-27 |
EP0272091A2 (en) | 1988-06-22 |
NO875194L (no) | 1988-06-16 |
EP0272091B2 (en) | 1998-10-28 |
NO171583C (no) | 1993-04-07 |
AU8249487A (en) | 1988-06-16 |
JP2677572B2 (ja) | 1997-11-17 |
NO171583B (no) | 1992-12-28 |
JPS63233915A (ja) | 1988-09-29 |
NO875194D0 (no) | 1987-12-14 |
DK651187A (da) | 1988-06-16 |
EP0272091B1 (en) | 1993-05-26 |
IE873387L (en) | 1988-06-15 |
DK651187D0 (da) | 1987-12-11 |
ES2056832T3 (es) | 1994-10-16 |
DE3786005T2 (de) | 1993-09-02 |
DE3786005D1 (de) | 1993-07-01 |
EP0272091A3 (en) | 1988-10-12 |
AU608264B2 (en) | 1991-03-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2056832T5 (es) | Vehiculo para la liberacion que contiene un agente activo asociado con una substancia anfifila. | |
AU1627588A (en) | Biodadhesion drug carriers for endothelial and epithelial uptake and lesional localization of therapeutic and diagnostic agents | |
DE69111821D1 (de) | In einem nichtwässrigen perfluorierten trägermedium suspendierte wirkstoffabgabevehikel. | |
DK1125577T3 (da) | Væskeformige medikamentindföringspræparater | |
DE69925936D1 (de) | Vorrichtung zur lokalen verabreichung einer arznei in einer körperhöhle | |
CY1108665T1 (el) | Διαταξεις χορηγησης φαρμακων παρατεταμενης απελευθερωσης, μεθοδοι χρησης και μεθοδοι κατασκευης αυτων | |
ATE152614T1 (de) | Mittel zur behandlung entzündeter gewebe | |
ES2027013T3 (es) | Un procedimiento para preparar una forma de dosificacion de liberacion controlada. | |
US4649075A (en) | Transdermal and transmucosal vortexed foam devices and the method of making | |
MX9306239A (es) | Composicion farmaceutica que forma un gel de lecitina in vivo para la liberacion mantenida de un compuesto biologicamente activo y procedimiento para la preparacion de la misma. | |
ES2188652T3 (es) | Sistema de direccionado de farmacos, metodos de fabricacion y uso del mismo. | |
ATE377414T1 (de) | Mikropartikel, geeignet als kontrastmittel im ultraschall und zur wirkstoffgabe in den blutkreislauf | |
DE69834025D1 (de) | Pharmazeutische zubereitungen und verfahren zu deren lokalen verabreichung | |
EE200000466A (et) | Omeprasooli mikrograanulid, nende valmistamismeetod ja farmatseutilised preparaadid | |
AR065073A2 (es) | Una formulacion medicamentosa de sistema de matriz que tiene liberacion controlada de un compuesto activo | |
US4892516A (en) | Surgical aid | |
YU49390A (sh) | Postupak za izradu transdermalnog terapijskog sistema sa stupnjevitim otpuštanjem aktivne materije | |
ES2138602T3 (es) | Agente terapeutico para la amenaza de aborto. | |
Nguyen et al. | Anaphylaxis to laminaria | |
MY110074A (en) | Pharmacuetical formulation. | |
NO973666D0 (no) | Kontrastmiddelholdige liposomer for avbildning av det intravaskulære rom | |
ES2040765T3 (es) | Procedimiento para preparar un agente para el tratamiento de enfermedades angiogenas o tumores. | |
Gröning et al. | P249 magnetic dosage forms with controlled gastric residence time | |
Pearson | Historical perspective of the treatment of osteosarcoma: an interview with Dr Norman Jaffe | |
Kuhland et al. | P250 controlled release of drugs from transdermal systems using pump mechanisms |