ES2055713T3 - Antibioticos con actividad antifungica. - Google Patents

Antibioticos con actividad antifungica.

Info

Publication number
ES2055713T3
ES2055713T3 ES88101410T ES88101410T ES2055713T3 ES 2055713 T3 ES2055713 T3 ES 2055713T3 ES 88101410 T ES88101410 T ES 88101410T ES 88101410 T ES88101410 T ES 88101410T ES 2055713 T3 ES2055713 T3 ES 2055713T3
Authority
ES
Spain
Prior art keywords
antibiotics
antifungal activity
cepa
atcc
antifungal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88101410T
Other languages
English (en)
Inventor
Toshikazu Oki
Kyoichiro Saitoh
Kozo Tomatsu
Koji Tomita
Masataka Konishi
Takeo Miyaki
Mitsuaki Tsunakawa
Maki Nishio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2055713T3 publication Critical patent/ES2055713T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LOS NUEVOS ANTIBIOTICOS AQUI DESIGNADOS COMO BU-3608, BU-3608B Y BU-3608C SE PRODUCEN POR FERMENTACION DE ACTINOMADURA HIBISCA CEPA NO. P157-2, ATCC 53557, Y CEPA NO. A278-4, ATCC 53646. LOS ANTIBIOTICOS TIENEN ACTIVIDADES ANTIFUNGICAS Y ANTIVIRICAS.
ES88101410T 1987-02-02 1988-02-01 Antibioticos con actividad antifungica. Expired - Lifetime ES2055713T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1005887A 1987-02-02 1987-02-02
US07/115,273 US4870165A (en) 1987-02-02 1987-11-02 Antifungal antibiotics

Publications (1)

Publication Number Publication Date
ES2055713T3 true ES2055713T3 (es) 1994-09-01

Family

ID=26680704

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101410T Expired - Lifetime ES2055713T3 (es) 1987-02-02 1988-02-01 Antibioticos con actividad antifungica.

Country Status (7)

Country Link
US (1) US4870165A (es)
EP (1) EP0277621B1 (es)
JP (1) JP2589730B2 (es)
CA (1) CA1309045C (es)
DE (1) DE3868284D1 (es)
ES (1) ES2055713T3 (es)
GR (1) GR3003732T3 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990497A (en) * 1987-02-02 1991-02-05 Toshikazu Oki Antifungal antibiotics
US5055453A (en) * 1987-11-02 1991-10-08 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Benanomicins a and antibiotic compositions
US5109122A (en) * 1987-11-02 1992-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antibiotics, dexylosylbenanomicin B
US5096817A (en) * 1988-06-07 1992-03-17 Bristol-Myers Company Process for producing antibiotics BU-3608 D and BU-3608 E
US4992425A (en) * 1988-06-07 1991-02-12 Bristol-Myers Company Antibiotics BU-3608D and BU-3608E
IL90783A (en) * 1988-07-01 1994-01-25 Bristol Myers Squibb Co Method for preventing the transmission of non-human living biological material to the VIH virus by using the antibiotic substance UB-8063
US4960755A (en) * 1988-07-19 1990-10-02 Bristol-Myers Company BU-3608 derivatives
JP2643340B2 (ja) * 1988-08-22 1997-08-20 財団法人微生物化学研究会 ヒト後天性免疫不全症候群ウイルス感染阻害剤
US5183808A (en) * 1988-11-10 1993-02-02 Bristol-Myers Squibb Company Method for treating fungal infections with serine analogs of BU-3608 antibiotics
US4973673A (en) * 1988-11-10 1990-11-27 Bristol-Myers Company Serine analogs of BU-3608 antibiotics
US5061624A (en) * 1988-11-10 1991-10-29 Bristol-Myers Company Serine analogs of BU-3608 antibiotics
US5114857A (en) * 1988-11-10 1992-05-19 Bristol-Myers Company Actinomadura hibisca microorganism useful for preparing serine analogs of BU-3608 antibiotics
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
US5053395A (en) * 1989-03-24 1991-10-01 Bristol-Myers Company Pradimicin amide derivatives
US5227370A (en) * 1989-11-14 1993-07-13 Bristol-Myers Squibb Company Pradimicin derivatives
FI92207C (fi) * 1989-11-14 1994-10-10 Squibb Bristol Myers Co Menetelmä terapeuttisesti käyttökelpoisten pradimisiinijohdannaisten valmistamiseksi
CA2030166C (en) * 1989-11-22 1997-10-07 Shimpei Aburaki Pradimicin derivatives
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
US5194371A (en) * 1991-07-31 1993-03-16 Bristol-Myers Squibb Company Production of pradimicin antibiotics
JP3134010B2 (ja) * 1991-11-26 2001-02-13 財団法人微生物化学研究会 デスアラニンベナノマイシンａ誘導体およびそれらの製造法
US5837828A (en) * 1992-04-08 1998-11-17 Bristol-Myers Squibb Co. Pradimicin derivatives
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
US5338728A (en) * 1992-08-14 1994-08-16 Bristol-Myers Squibb Pradimicin compounds
WO1997027860A1 (en) * 1996-01-31 1997-08-07 Merck & Co., Inc. Antifungal agent

Also Published As

Publication number Publication date
DE3868284D1 (de) 1992-03-19
JP2589730B2 (ja) 1997-03-12
EP0277621B1 (en) 1992-02-05
EP0277621A1 (en) 1988-08-10
CA1309045C (en) 1992-10-20
JPS63270696A (ja) 1988-11-08
US4870165A (en) 1989-09-26
GR3003732T3 (es) 1993-03-16

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