ES2055456T3 - D8- y d9-prostaglandina, proceso para su obtencion y uso farmaceutico de los mismos. - Google Patents

D8- y d9-prostaglandina, proceso para su obtencion y uso farmaceutico de los mismos.

Info

Publication number
ES2055456T3
ES2055456T3 ES90917918T ES90917918T ES2055456T3 ES 2055456 T3 ES2055456 T3 ES 2055456T3 ES 90917918 T ES90917918 T ES 90917918T ES 90917918 T ES90917918 T ES 90917918T ES 2055456 T3 ES2055456 T3 ES 2055456T3
Authority
ES
Spain
Prior art keywords
prostaglandine
pharmaceutical use
hydrogen
group
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90917918T
Other languages
English (en)
Inventor
Ulrich Klar
Hartmut Rehwinkel
Helmut Vorbruggen
Karl-Heinz Thierauch
Claus-Steffen Sturzebecher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2055456T3 publication Critical patent/ES2055456T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION SE REFIERE A UN DERIVADO DE POSTAGLANDINA DE FORMULA (I), Y SUS SALES BASICAS TOLERABLES FISIOLOGICAMENTE Y LOS XA, R-CICLODEXTRINATARTRATOS DE FORMULA (I). SE DESCRIBE LA APLICACION DE LA FORM.(I) COMO FARMACO, Y LOS COMPUESTOS DE DICHA FORM. ENCAPSULADOS CON LIPOSOMAS. SIENDO (C) EL RESTO, (B) R ELEVADO A 1, (D), (E) O-COHWR ELEVADO A 5; R ELEVADO A 1 Y R ELEVADO A 3 HIDROGENO O UN GRUPO HIDRO; R ELEVADO A 4 HIDROGENO Y X O, S, W, H, -OR ELEVADO A 6, HCL, CN, NO SUB 2 Y OTROS.
ES90917918T 1989-07-14 1990-07-13 D8- y d9-prostaglandina, proceso para su obtencion y uso farmaceutico de los mismos. Expired - Lifetime ES2055456T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3923798A DE3923798A1 (de) 1989-07-14 1989-07-14 (delta)(pfeil hoch)8(pfeil hoch)-und(delta)(pfeil hoch)9(pfeil hoch)-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
ES2055456T3 true ES2055456T3 (es) 1994-08-16

Family

ID=6385317

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90917918T Expired - Lifetime ES2055456T3 (es) 1989-07-14 1990-07-13 D8- y d9-prostaglandina, proceso para su obtencion y uso farmaceutico de los mismos.

Country Status (8)

Country Link
EP (1) EP0434832B1 (es)
JP (1) JPH04502330A (es)
AT (1) ATE105184T1 (es)
CA (1) CA2036383A1 (es)
DE (2) DE3923798A1 (es)
DK (1) DK0434832T3 (es)
ES (1) ES2055456T3 (es)
WO (1) WO1991001303A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4024345A1 (de) * 1990-07-27 1992-01-30 Schering Ag Cyclopentenderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7414650A (nl) * 1974-11-11 1976-05-13 Akzo Nv Nieuwe prostaglandine analoga.
US4201873A (en) * 1975-09-17 1980-05-06 The Upjohn Company 9-Deoxy-9,10-didehydro-PGD2 analogs
GB1539268A (en) * 1976-12-23 1979-01-31 Ici Ltd Prostane derivatives
DE3125271A1 (de) * 1981-06-24 1983-01-13 Schering Ag, 1000 Berlin Und 4619 Bergkamen (delta)(pfeil hoch)8(pfeil hoch),(pfeil hoch)9(pfeil hoch)-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS591463A (ja) * 1982-06-28 1984-01-06 Ono Pharmaceut Co Ltd 新規なプロスタグランジンｄ類似化合物
EP0172963A1 (en) * 1984-08-30 1986-03-05 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and compositions containing them

Also Published As

Publication number Publication date
JPH04502330A (ja) 1992-04-23
DE3923798A1 (de) 1991-01-17
EP0434832B1 (de) 1994-05-04
EP0434832A1 (de) 1991-07-03
CA2036383A1 (en) 1991-01-15
ATE105184T1 (de) 1994-05-15
DK0434832T3 (da) 1994-08-29
WO1991001303A1 (de) 1991-02-07
DE59005620D1 (de) 1994-06-09

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