ES2045036T3 - Procedimiento para la obtencion de n-etilpiperazina. - Google Patents

Procedimiento para la obtencion de n-etilpiperazina.

Info

Publication number
ES2045036T3
ES2045036T3 ES88112507T ES88112507T ES2045036T3 ES 2045036 T3 ES2045036 T3 ES 2045036T3 ES 88112507 T ES88112507 T ES 88112507T ES 88112507 T ES88112507 T ES 88112507T ES 2045036 T3 ES2045036 T3 ES 2045036T3
Authority
ES
Spain
Prior art keywords
kilos
water
obtaining
ethylpiperacine
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88112507T
Other languages
English (en)
Inventor
Herbert Dr Muller
Dieter Dr Franz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2045036T3 publication Critical patent/ES2045036T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/023—Preparation; Separation; Stabilisation; Use of additives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S203/00—Distillation: processes, separatory
    • Y10S203/13—Spirits

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA OBTENCION DESTILATIVA DE N - ETILPIPERACINA DA MEZCLAS COMPUESTAS DE; A = 30 A 90 KILOS DE N - ETILPIPERACINA B = 7 A 40 KILOS DE N, N''- DIETILPIPERACINA C = 3 A 29 KILOS DE PIPERACINA D = 0 A 30 KILOS DE ETANOL E = 0 A 40 KILOS DE AGUA, ASI COMO F = 0 A 5 KILOS DE IMPUREZAS POR CADA 100 KILOS, DURANTE EL PASADO SE EFECTUABA LA DESTILACION DE AGUA X = Y+E=3B BIS 12B EN DONDE Y ES AQUELLA AGUA EN CANTIDAD QUE EN SU CASO ESTA AÑADIDA PARA EL CUMPLIMIENTO DE ESTA CONDICION, Y QUE DE ESTAS MEZCLAS SE SEPARE UNA TRAS OTRA LAS FRACCIONES 1) AGUA, ETANOL, N, N''- DIETILPIPERACINA Y DEMAS IMPUREZAS LIGERAMENTE VOLATILES 2) AGUA A VECES SE PRESENTA EN EXCESO 3) PIPERACINA, Y 4) N - ETILPIPERACINA PURO COMO PRODUCTO FINAL.
ES88112507T 1987-08-05 1988-08-02 Procedimiento para la obtencion de n-etilpiperazina. Expired - Lifetime ES2045036T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873725925 DE3725925A1 (de) 1987-08-05 1987-08-05 Verfahren zur gewinnung von n-ethylpiperazin

Publications (1)

Publication Number Publication Date
ES2045036T3 true ES2045036T3 (es) 1994-01-16

Family

ID=6333078

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88112507T Expired - Lifetime ES2045036T3 (es) 1987-08-05 1988-08-02 Procedimiento para la obtencion de n-etilpiperazina.

Country Status (4)

Country Link
US (1) US4911793A (es)
EP (1) EP0302440B1 (es)
DE (2) DE3725925A1 (es)
ES (1) ES2045036T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4427511A1 (de) * 1994-08-03 1996-02-08 Basf Ag Verfahren zur destillativen Gewinnung von N-Ethylpiperazin
DE10221122A1 (de) * 2002-05-13 2003-12-04 Bayer Ag Verfahren zur schonenden destillativen Trennung von Stoffgemischen
DE102004038107A1 (de) * 2004-08-05 2006-03-16 Basf Ag Verfahren zur Verbesserung der Farbstabilität von Piperazin
US8895785B2 (en) 2010-12-21 2014-11-25 Dow Global Technologies Llc Processes for separating one or more amine byproducts from one or more desired amines
CN104230941B (zh) * 2013-06-17 2016-08-10 中国石油化工股份有限公司 三乙烯二胺的生产方法
CN104230850B (zh) * 2013-06-17 2016-04-13 中国石油化工股份有限公司 哌嗪的分离方法
CN104230940B (zh) * 2013-06-17 2016-08-10 中国石油化工股份有限公司 三乙烯二胺的分离方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126383A (en) * 1964-03-24 Method for recovering alkylamine-free
US3154552A (en) * 1961-06-21 1964-10-27 Wyandotte Chemicals Corp Methylation of piperazines
US3159633A (en) * 1961-06-21 1964-12-01 Wyandotte Chemicals Corp Methylation of piperazines
US3128275A (en) * 1962-06-07 1964-04-07 Jefferson Chem Co Inc Method for the purification of triethylenediamine
AT283373B (de) * 1967-11-24 1970-08-10 Basf Ag Verfahren zur Herstellung von N-Methylpiperazin
DE3440195A1 (de) * 1984-11-03 1986-05-07 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 1-alkyl- oder 1-cycloalkylpiperazinen

Also Published As

Publication number Publication date
DE3725925A1 (de) 1989-02-16
US4911793A (en) 1990-03-27
EP0302440B1 (de) 1992-10-28
EP0302440A3 (en) 1990-03-07
EP0302440A2 (de) 1989-02-08
DE3875547D1 (de) 1992-12-03

Similar Documents

Publication Publication Date Title
MX171861B (es) Composiciones medicinales acuosas que contienen un factor de crecimiento poli-peptidico y el metodo para estabilizar las mismas
DE3577851D1 (de) Inositoltriphosphat, verfahren zu seiner herstellung und dieses enthaltende zubereitung.
DE58902737D1 (de) Verfahren zur herstellung pharmazeutischer mischungen.
PT81839B (pt) Processo de preparacao de formulacoes com propulsores de aerosol a base de clorofluorocarbono contendo medicamento
DE68923819T2 (de) Verwendung von gamma-Hydroxy-Buttersäuresalzen zur Herstellung von pharmazeutischen Zusammensetzungen zur Verwendung bei der Behandlung von Alkoholismus und die hergestellten Zusammensetzungen.
ES547618A0 (es) Aparato para calcular la concentracion de alcohol en el cuerpo
DE3752112D1 (de) Verwendung von Inositoltriphosphat zur Behandlung von Entzündungen
PT86828A (pt) Verfahren zur herstellung eines pharmazeutischen pflasters
DE3889139T2 (de) Abwehrmittel.
ES504724A0 (es) Procedimiento para la fabricacion de bases soportadoras para maquinaria en general.
ES2170259T3 (es) Empleo de lipidos como agentes auxiliares en la obtencion de formas farmaceuticas solidas segun el procedimiento de extrusion en fusion.
BR8905541A (pt) Dispositivo para a determinacao da concentracao de pelo menos uma substancia presente no tecido organico
ES2045036T3 (es) Procedimiento para la obtencion de n-etilpiperazina.
AT355726B (de) Verfahren zur herstellung von ihren wirkstoff geregelt abgebenden biologisch aktiven praeparaten
ES2058149T3 (es) 3,4-dihidro-2h-benzopiranos sustiuidos, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.
MX9101035A (es) Quinazolinonas biologicamente activas y composicion farmaceutica que las contiene
PT71408A (de) Verfahren zur herstellung von 1-alkadien-2,4-yl-2-hidroxymethyl-3,4,5-trimydroxypiperidinen mit wirkung uber die kohlehydraten und/oder fettwechsel und von diesen verbindungen enthaltenden pharmazeutischen und/oder tierartzleichen praparaten
AT359506B (de) Verfahren zur herstellung von neuen, hetero- cyclischen pyrimido(1,2-a)-verbindungen und deren optisch aktiven isomeren
DE69012589T2 (de) Verfahren zur herstellung von kontinuierlich stirngefrästen kegelzahnrädern mit abgeschrägten zahnstirnkanten.
DE3678657D1 (de) In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine.
DE68914913D1 (de) Verfahren zur Herstellung von 2-Aminopurin.
MX9401172A (es) Derivados fluorados de 4-aminoandrostadienona, procesamiento para su preparacion y composiciones farmaceuticas que los contienen.
ATE2327T1 (de) Pyrazincarboxamide, verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES493572A0 (es) Un metodo para el tratamiento o elaboracion de filamentos sinteticos en su fabricacion
ATE8798T1 (de) Kijanimicin, es enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung von kijanimicin und der zusammensetzungen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 302440

Country of ref document: ES