ES2041719T3 - Procedimiento para la obtencion de un agente antiulcerogeno. - Google Patents
Procedimiento para la obtencion de un agente antiulcerogeno.Info
- Publication number
- ES2041719T3 ES2041719T3 ES88104306T ES88104306T ES2041719T3 ES 2041719 T3 ES2041719 T3 ES 2041719T3 ES 88104306 T ES88104306 T ES 88104306T ES 88104306 T ES88104306 T ES 88104306T ES 2041719 T3 ES2041719 T3 ES 2041719T3
- Authority
- ES
- Spain
- Prior art keywords
- alcohyl
- atom
- antiulcerogenous
- procedure
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
DERIVADOS BENZOFURANOS DE LA FORMULA GENERAL I CON LO CUAL R1 Y R2 PARA HIDROGENOS, ALCOHILO O FENILALCOHILO CON 1 HASTA 4 ATOMOS DE CARBONO EN EL RESTO ALQUILO RESPECTIVAMENTE, Y R4, QUE SON IGUAL O R3 DIFERENTE, PARA HIDROGENOS O C1 - C4 - ALCOHILO O JUNTOS PARA UNA CADENA DE 3 HASTA 5 ESLABONES, QUE PUEDE SER INTERRUMPIDO A TRAVES DE UN ATOMO DE OSIGENO O UN GRUPO - NR1, X PARA - CO - CH = CH -, - CO - CH2 - CH2 - O - CHOH - CH2 CH2, N PARA 2 O 3 Y HET PARA UN ANILLO AROMATICO DE 5 ESLABONES, EL CUAL QUE UN O - O S - ATOMO PARA UN ANILLO AROMATICO DE 5 O 6 ESLABONES, EL CUAL QUE CONTIENE UN HETEROATOMO DEL GRUPO N, O Y S Y DADO EL CASO EN ADICION UN N ATOMO (SUPLEMENTARIO), CON LO CUAL EL ANILLO PUEDE SER SUSTITUIDO A TRAVES C1 - C4 - ALCOHILO, FLUOR, CLORO, BROMO, NH2 O NR1R2, CON LO CUAL R1 Y R2 TIENEN LA SIGNIFICACION MENCIONADA POR ARRIBA. LA UTILIZACION DE ESTOS DERIVADOS BENZOFURANOS A LA FABRICACION DE AGENTES FARMACEUTICOS, PARTICULARMENTE ANTIULCEROGENOS Y ESTOS AGENTES PROPIOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873710469 DE3710469A1 (de) | 1987-03-30 | 1987-03-30 | Neue benzofuranderivate und diese enthaltende therapeutische mittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2041719T3 true ES2041719T3 (es) | 1995-04-01 |
Family
ID=6324338
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88104306T Expired - Lifetime ES2041719T3 (es) | 1987-03-30 | 1988-03-18 | Procedimiento para la obtencion de un agente antiulcerogeno. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4845096A (es) |
EP (1) | EP0284914B1 (es) |
JP (1) | JPS63258473A (es) |
AT (1) | ATE68494T1 (es) |
DE (2) | DE3710469A1 (es) |
ES (1) | ES2041719T3 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4225053A1 (de) * | 1992-07-29 | 1994-02-03 | Basf Ag | Verfahren zur Herstellung von 4-Dialkoxymethylpyrazolen |
DE69805596T2 (de) * | 1997-12-16 | 2002-11-28 | Ssp Co | Imidazol-Derivat und dieses als aktiven Bestandteil enthaltendes Arzneimittel |
AUPS110302A0 (en) * | 2002-03-14 | 2002-04-18 | Biomolecular Research Institute Limited | Novel chalcone derivatives and uses thereof |
US7223161B2 (en) * | 2004-06-29 | 2007-05-29 | Goei Co., Ltd. | Cutting apparatus with dust discharging |
US8063093B2 (en) * | 2005-03-15 | 2011-11-22 | Andrew J Harvey | Potassium channel blockers and uses thereof |
AU2007304880B9 (en) * | 2006-10-04 | 2012-11-08 | Bionomics Limited | Novel benzofuran potassium channel blockers and uses thereof |
AU2007304881B2 (en) | 2006-10-04 | 2013-03-07 | Bionomics Limited | Novel chromenone potassium channel blockers and uses thereof |
US7737157B2 (en) * | 2008-08-29 | 2010-06-15 | Hutchison Medipharma Enterprises Limited | Pyrimidine compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1216381A (en) * | 1968-07-06 | 1970-12-23 | Delalande Sa | Derivatives of benzimidazolyl-2-methyl piperazine and process for their preparation |
GB1209558A (en) * | 1968-07-06 | 1970-10-21 | Delalande Sa | Derivatives of 5-cinnamoyl benzofuran and process for their preparation |
BE786362A (fr) * | 1971-07-26 | 1973-01-17 | Delalande Sa | Nouveaux derives de gamma-dialkylaminoalkoxy-6 dimethoxy-4,7 benzofurannes, leur procede de preparation et leur application en therapeutique |
BE787838R (fr) * | 1971-08-25 | 1973-02-22 | Delalande Sa | Nouveaux derives du cinnamoyl-5 benzofuranne, leur procede de preparation et leur utilisation en therapeutique |
JPS5118947A (en) * | 1974-08-08 | 1976-02-14 | Mitsutoyo Seisakusho | Keisokuki toni kokushokukuromutokinnyori memori moyotoohodokosuhoho |
US4153620A (en) * | 1976-07-12 | 1979-05-08 | Delalande S.A. | Certain N-5-[4,7-dimethoxy)-6-(monoalkylaminoethoxy, monocycloalkylaminoethoxy, or dialkylaminoethoxy) benzofuranyl], N'-methyl or ethyl ureas |
CH625234A5 (es) * | 1976-07-12 | 1981-09-15 | Delalande Sa |
-
1987
- 1987-03-30 DE DE19873710469 patent/DE3710469A1/de not_active Withdrawn
-
1988
- 1988-03-18 ES ES88104306T patent/ES2041719T3/es not_active Expired - Lifetime
- 1988-03-18 EP EP88104306A patent/EP0284914B1/de not_active Expired - Lifetime
- 1988-03-18 DE DE8888104306T patent/DE3865480D1/de not_active Expired - Lifetime
- 1988-03-18 AT AT88104306T patent/ATE68494T1/de active
- 1988-03-18 US US07/170,321 patent/US4845096A/en not_active Expired - Fee Related
- 1988-03-30 JP JP63074866A patent/JPS63258473A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0284914B1 (de) | 1991-10-16 |
DE3865480D1 (de) | 1991-11-21 |
EP0284914A1 (de) | 1988-10-05 |
JPS63258473A (ja) | 1988-10-25 |
DE3710469A1 (de) | 1988-10-20 |
US4845096A (en) | 1989-07-04 |
ATE68494T1 (de) | 1991-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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