ES2038684T3 - Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion. - Google Patents

Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion.

Info

Publication number
ES2038684T3
ES2038684T3 ES198787402354T ES87402354T ES2038684T3 ES 2038684 T3 ES2038684 T3 ES 2038684T3 ES 198787402354 T ES198787402354 T ES 198787402354T ES 87402354 T ES87402354 T ES 87402354T ES 2038684 T3 ES2038684 T3 ES 2038684T3
Authority
ES
Spain
Prior art keywords
preparation
derivatives
procedure
octahidroindol
intermediate compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787402354T
Other languages
English (en)
Spanish (es)
Inventor
Francis Brion
Jean Buendia
Christian Marie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of ES2038684T3 publication Critical patent/ES2038684T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/08—Saturated compounds having a carboxyl group bound to a six-membered ring
    • C07C61/09—Completely hydrogenated benzenedicarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Lubricants (AREA)
  • Liquid Developers In Electrophotography (AREA)
ES198787402354T 1986-10-22 1987-10-21 Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion. Expired - Lifetime ES2038684T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8614650A FR2605630B1 (fr) 1986-10-22 1986-10-22 Procede de preparation de derives de l'octahydroindole et intermediaires de preparation

Publications (1)

Publication Number Publication Date
ES2038684T3 true ES2038684T3 (es) 1993-08-01

Family

ID=9340061

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787402354T Expired - Lifetime ES2038684T3 (es) 1986-10-22 1987-10-21 Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion.

Country Status (14)

Country Link
US (1) US4879392A (enExample)
EP (1) EP0267098B1 (enExample)
JP (1) JPH082873B2 (enExample)
AT (1) ATE71937T1 (enExample)
CA (1) CA1292001C (enExample)
DE (1) DE3776273D1 (enExample)
DK (1) DK170095B1 (enExample)
ES (1) ES2038684T3 (enExample)
FI (1) FI84473C (enExample)
FR (1) FR2605630B1 (enExample)
GR (1) GR3004338T3 (enExample)
HU (1) HU198452B (enExample)
IE (1) IE60280B1 (enExample)
PT (1) PT85964B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19801646A1 (de) * 1998-01-17 1999-07-22 Bayer Ag Substituierte alpha,beta-annellierte Butyrolactone
DE19900205A1 (de) * 1999-01-07 2000-07-13 Basf Ag Verfahren zur Herstellung von (2S,4R,9S)-Octahydro-1H-indol-2-carbonsäure und Zwischenprodukte dafür
BR0308118A (pt) * 2002-03-01 2005-01-11 Warner Lambert Co Método para o tratamento de osteoartrite
JP4884758B2 (ja) * 2005-12-12 2012-02-29 株式会社フジキン エントランス絞り溝付微小流量制御装置の設計方法、
US7570523B2 (en) * 2006-07-31 2009-08-04 Sandisk 3D Llc Method for using two data busses for memory array block selection
CN102498098A (zh) * 2009-07-16 2012-06-13 艾博特公司 作为群多普利中间体的(2S，3aR，7aS)-八氢-1H-吲哚羧酸的合成方法
AU2014200205B2 (en) * 2010-05-24 2016-03-31 Bgp Products Operations Gmbh Preparation of (3aS,7aR)-hexahydroisobenzofuran-1(3H)-one by catalyzed biological resolution of dimethyl cyclohexane-1,2-dicarboxylate
CN102947461B (zh) * 2010-05-24 2015-01-28 雅培生产操作公司 通过环己烷-1,2-二羧酸二甲酯的催化生物拆分制备(3aS,7aR)-六氢异苯并呋喃-1(3H)-酮
CN103360299B (zh) * 2012-04-06 2017-03-01 武汉启瑞药业有限公司 群多普利中间体的异构体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2315661A (en) * 1939-05-27 1943-04-06 Winthrop Chem Co Inc Manufacture of nitrile compounds
DE1695609A1 (de) * 1967-01-12 1972-02-24 Ruetgerswerke Ag Verfahren zur Herstellung von Indolyl-3-acetonitril
US4156016A (en) * 1977-03-03 1979-05-22 Hoffmann-La Roche Inc. Indole compounds and process for their preparation
CA1125783A (en) * 1978-03-27 1982-06-15 Michael E. Condon Thioalkanoylalkanoic acid compounds
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
IE55867B1 (en) * 1981-12-29 1991-02-14 Hoechst Ag New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
US4490386A (en) * 1982-09-23 1984-12-25 Warner-Lambert Company Phosphate salts of 1-[2-[(1-alkoxycarbonyl-3-aralkyl)-amino]-1-oxoalkyl]octahydro-1H-indole-2-carboxylic acids, preparation of, and medical compositions thereof

Also Published As

Publication number Publication date
DE3776273D1 (de) 1992-03-05
FI874639L (fi) 1988-04-23
GR3004338T3 (enExample) 1993-03-31
FR2605630B1 (fr) 1989-06-30
FI874639A0 (fi) 1987-10-21
ATE71937T1 (de) 1992-02-15
DK550587D0 (da) 1987-10-21
FI84473B (fi) 1991-08-30
PT85964A (fr) 1987-11-01
US4879392A (en) 1989-11-07
PT85964B (pt) 1990-07-31
DK550587A (da) 1988-04-23
FI84473C (fi) 1991-12-10
FR2605630A1 (fr) 1988-04-29
CA1292001C (fr) 1991-11-12
IE60280B1 (en) 1994-06-29
IE872652L (en) 1988-04-22
EP0267098B1 (fr) 1992-01-22
JPH082873B2 (ja) 1996-01-17
HUT45494A (en) 1988-07-28
DK170095B1 (da) 1995-05-22
JPS63104957A (ja) 1988-05-10
HU198452B (en) 1989-10-30
EP0267098A1 (fr) 1988-05-11

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