ES2038185T3 - Procedimiento para preparar inhibidores de dopamina-beta-hidroxilasa. - Google Patents

Procedimiento para preparar inhibidores de dopamina-beta-hidroxilasa.

Info

Publication number
ES2038185T3
ES2038185T3 ES198787307259T ES87307259T ES2038185T3 ES 2038185 T3 ES2038185 T3 ES 2038185T3 ES 198787307259 T ES198787307259 T ES 198787307259T ES 87307259 T ES87307259 T ES 87307259T ES 2038185 T3 ES2038185 T3 ES 2038185T3
Authority
ES
Spain
Prior art keywords
beta
procedure
hydroxylase inhibitors
preparing dopamine
dopamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787307259T
Other languages
English (en)
Inventor
Joseph Alan Finkelstein
James Simpson Frazee
Carl Kaiser
Lawrence Ivan Kruse
Thomas Brent Leonard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2038185T3 publication Critical patent/ES2038185T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

POTENTES INHIBIDORES DBH CON FORMULA (I) PUEDEN UTILIZARSE PARA INHIBIR LA ACTIVIDAD DBH EN MAMIFEROS.
ES198787307259T 1986-08-18 1987-08-17 Procedimiento para preparar inhibidores de dopamina-beta-hidroxilasa. Expired - Lifetime ES2038185T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89816586A 1986-08-18 1986-08-18

Publications (1)

Publication Number Publication Date
ES2038185T3 true ES2038185T3 (es) 1993-07-16

Family

ID=25409053

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787307259T Expired - Lifetime ES2038185T3 (es) 1986-08-18 1987-08-17 Procedimiento para preparar inhibidores de dopamina-beta-hidroxilasa.

Country Status (15)

Country Link
EP (2) EP0260814B1 (es)
CN (1) CN87105734A (es)
AT (1) ATE72430T1 (es)
AU (1) AU7910287A (es)
DE (1) DE3776613D1 (es)
DK (1) DK210488A (es)
ES (1) ES2038185T3 (es)
GR (1) GR3004345T3 (es)
HU (2) HU911945D0 (es)
NZ (1) NZ221427A (es)
PH (1) PH23530A (es)
PT (1) PT85547B (es)
WO (1) WO1988001267A1 (es)
ZA (1) ZA876073B (es)
ZW (1) ZW15387A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835154A (en) * 1987-06-01 1989-05-30 Smithkline Beckman Corporation 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
FR2928544A1 (fr) * 2008-03-17 2009-09-18 Oreal Utilisation d'inhibiteurs de la dopamine-beta hydroxylase pour la pigmentation capillaire.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
US4532331A (en) * 1983-04-12 1985-07-30 Smithkline Beckman Corporation 1-Benzyl-2-aminomethyl imidazole derivatives

Also Published As

Publication number Publication date
ZW15387A1 (en) 1987-11-18
EP0288488A1 (en) 1988-11-02
GR3004345T3 (es) 1993-03-31
CN87105734A (zh) 1988-02-24
EP0288488A4 (en) 1990-09-12
HU204037B (en) 1991-11-28
ZA876073B (en) 1988-08-31
PH23530A (en) 1989-08-25
HU911945D0 (en) 1991-12-30
DK210488D0 (da) 1988-04-18
WO1988001267A1 (en) 1988-02-25
AU7910287A (en) 1988-03-08
HUT50461A (en) 1990-02-28
EP0260814B1 (en) 1992-02-05
DE3776613D1 (de) 1992-03-19
PT85547A (pt) 1988-08-17
PT85547B (pt) 1995-03-01
ATE72430T1 (de) 1992-02-15
DK210488A (da) 1988-04-18
EP0260814A1 (en) 1988-03-23
NZ221427A (en) 1990-12-21

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