ES2036173T3 - 1,4-dihidropiridinas marcadas con 35s, procedimiento para su obtencion y su empleo. - Google Patents

1,4-dihidropiridinas marcadas con 35s, procedimiento para su obtencion y su empleo.

Info

Publication number
ES2036173T3
ES2036173T3 ES198686117975T ES86117975T ES2036173T3 ES 2036173 T3 ES2036173 T3 ES 2036173T3 ES 198686117975 T ES198686117975 T ES 198686117975T ES 86117975 T ES86117975 T ES 86117975T ES 2036173 T3 ES2036173 T3 ES 2036173T3
Authority
ES
Spain
Prior art keywords
chain
carbon atoms
optionally substituted
dihydropyridines
cyano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686117975T
Other languages
English (en)
Inventor
Hartmut Prof.Dr. Glossmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2036173T3 publication Critical patent/ES2036173T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Dihidropiridinas marcadas radioactivamente de la fórmula (I) en la que R 1 significa 2-nitrofenilo, 3-nitrofenilo, 2,3 -diclorofenilo, 2-clorofenilo, 2-trifluormetilfenilo, 2-difl uormetoxifenilo o benzoxadiazolilo, R 2 significa alquilo de cadena lienal o ramificada con hasta 6 átomos de carbono, que está substituido en caso dado por fluor, cloro, bromo, N-bencil-N-metilamino o por metoxi, y R 3 , R 4 son iguales o diferentes y significan respectivamente alquilo de cadena lineal o ramificada con hasta 4 átomos de carbono, o significa hidroximetilo. (Reserva del art. 167.2 CPE).
ES198686117975T 1986-01-11 1986-12-23 1,4-dihidropiridinas marcadas con 35s, procedimiento para su obtencion y su empleo. Expired - Lifetime ES2036173T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863600593 DE3600593A1 (de) 1986-01-11 1986-01-11 (pfeil hoch)3(pfeil hoch)(pfeil hoch)5(pfeil hoch)s markierte 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ES2036173T3 true ES2036173T3 (es) 1993-05-16

Family

ID=6291661

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686117975T Expired - Lifetime ES2036173T3 (es) 1986-01-11 1986-12-23 1,4-dihidropiridinas marcadas con 35s, procedimiento para su obtencion y su empleo.

Country Status (6)

Country Link
US (1) US4794187A (es)
EP (1) EP0229383B1 (es)
JP (1) JPS62195364A (es)
AT (1) ATE55989T1 (es)
DE (2) DE3600593A1 (es)
ES (1) ES2036173T3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63135381A (ja) * 1986-11-26 1988-06-07 Kyorin Pharmaceut Co Ltd 多剤耐性癌細胞に対する感受性増強剤及びその製造方法
US5296693A (en) * 1991-12-16 1994-03-22 Canon Kabushiki Kaisha Ink intrusion resistant digital code
US20050020672A1 (en) * 1994-04-08 2005-01-27 The Procter & Gamble Company Methods of extending mammalian life span via iron chelating compounds that reduce free radical damage in mammals
EP3087054A4 (en) 2013-12-27 2017-10-25 Novus International Inc. Ethoxylated surfactants
CN105319353A (zh) * 2014-07-23 2016-02-10 江苏维赛科技生物发展有限公司 一种检测二氢吡啶类药物残留的酶联免疫试剂盒的制备
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3341806A1 (de) * 1983-11-19 1985-05-30 Glossmann, Hartmut, Prof.Dr.med., 6301 Heuchelheim Radioaktiv mit (pfeil hoch)1(pfeil hoch)(pfeil hoch)2(pfeil hoch)(pfeil hoch)5(pfeil hoch)i-markierte 1,4-dihydropyridinderivate und 1,4-dihydrochinolinderivate, ihre herstellung und ihre verwendung zur auspruefung von arzneimitteln
GB8422606D0 (en) * 1984-09-07 1984-10-10 Amersham Int Plc Labelling organic molecules

Also Published As

Publication number Publication date
US4794187A (en) 1988-12-27
ATE55989T1 (de) 1990-09-15
EP0229383A2 (de) 1987-07-22
DE3600593A1 (de) 1987-07-16
JPS62195364A (ja) 1987-08-28
DE3673793D1 (de) 1990-10-04
EP0229383A3 (en) 1988-10-05
EP0229383B1 (de) 1990-08-29

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