ES2034888B1 - Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata. - Google Patents

Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata.

Info

Publication number
ES2034888B1
ES2034888B1 ES9101710A ES9101710A ES2034888B1 ES 2034888 B1 ES2034888 B1 ES 2034888B1 ES 9101710 A ES9101710 A ES 9101710A ES 9101710 A ES9101710 A ES 9101710A ES 2034888 B1 ES2034888 B1 ES 2034888B1
Authority
ES
Spain
Prior art keywords
recutable
procedure
consequentials
consequential
total acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9101710A
Other languages
English (en)
Other versions
ES2034888A1 (es
Inventor
Rodero Miguel Angel Salinero
Toral M Angeles Sevilla
Del Corral Jose Maria Miguel
Gomez M Jose Montero
Feliciano Martin Arturo San
Roman Del Barrio Luis San
Gabarro Jose Antonio Poch
Armengol Antonio Manes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus SA
Original Assignee
Laboratorios Madaus Cerafarm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Madaus Cerafarm SA filed Critical Laboratorios Madaus Cerafarm SA
Priority to ES9101710A priority Critical patent/ES2034888B1/es
Priority to EP92500088A priority patent/EP0527101A1/en
Priority to US07/911,613 priority patent/US5284873A/en
Priority to JP4184146A priority patent/JPH05194250A/ja
Publication of ES2034888A1 publication Critical patent/ES2034888A1/es
Application granted granted Critical
Publication of ES2034888B1 publication Critical patent/ES2034888B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

EL PROCEDIMIENTO DE LA PRESENTE INVENCION CONSISTE EN SOMETER EL EXTRACTO LIPIDICO DE LA PLANTA SABAL SERRULATA A UNA SAPONIFICACION EXHAUSTIVA EN MEDIO ACUOSO ALCALINO, ELIMINAR LA FRACCION INSAPONIFICABLE MEDIANTE EXTRACCION CON DISOLVENTES APOLARES, Y RECUPERAR LA FRACCION CONSTITUIDA ESENCIALMENTE POR LOS ACIDOS GRASOS TOTALES MEDIANTE ACIDIFICACION A PH INFERLOR A 4 Y EXTRACCION CON DISOLVENTES APOLARES. LA FRACCION ACIDA TOTAL ASI OBTENIDA MANIFIESTA UNA EFICAZ ACCION BLOQUEANTE DE LOS RECEPTORES X-ADRENERGICOS, DESCONOCIDA HASTA LA FECHA, QUE PERMITE SU EMPLEO EN LA PRECARACION DE COMPOSICIONES FARMACEUTICAS DE UTILIDAD, ENTRE OTRAS, EN EL TRATAMIENTO DE LOS ENFERMOS PROSTATICOS.
ES9101710A 1991-07-11 1991-07-11 Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata. Expired - Fee Related ES2034888B1 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES9101710A ES2034888B1 (es) 1991-07-11 1991-07-11 Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata.
EP92500088A EP0527101A1 (en) 1991-07-11 1992-07-09 New pharmaceutical compositions derived from acid fraction of the lipid extracts of sabal serrulata, with antagonistic adrenergic effect and method to obtain these compositions
US07/911,613 US5284873A (en) 1991-07-11 1992-07-10 Pharmaceutical compositions derived from the acid fraction of lipid extracts of sabal serrulata, with adrenergic antagonist activity and method of preparing said composition
JP4184146A JPH05194250A (ja) 1991-07-11 1992-07-10 サバルセルラタのリピド抽出物の酸分画から導かれた新規薬学的組成物及びその組成物を製造する方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9101710A ES2034888B1 (es) 1991-07-11 1991-07-11 Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata.

Publications (2)

Publication Number Publication Date
ES2034888A1 ES2034888A1 (es) 1993-04-01
ES2034888B1 true ES2034888B1 (es) 1994-02-16

Family

ID=8273084

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9101710A Expired - Fee Related ES2034888B1 (es) 1991-07-11 1991-07-11 Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata.

Country Status (4)

Country Link
US (1) US5284873A (es)
EP (1) EP0527101A1 (es)
JP (1) JPH05194250A (es)
ES (1) ES2034888B1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6039950A (en) * 1995-04-14 2000-03-21 University Of Southern California Pharmaceutical grade saw palmetto
BR9917806B1 (pt) * 1998-01-21 2013-06-18 composiÇço de feromona para tratamento de estresse ou ansiedade em mamÍferos, e soluÇço.
PT948963E (pt) * 1998-01-21 2003-09-30 Fideline Feromonas tranquilizantes para diminuir o stress a ansiedade e a agressividade dos porcos
GB9808796D0 (en) * 1998-04-24 1998-06-24 Rowett Research Services Limit Antithrombotic agents
US6759063B2 (en) 1999-09-27 2004-07-06 Anthony L. Almada Methods and compositions for reducing sympathomimetic-induced side effects
US6200573B1 (en) * 1999-12-03 2001-03-13 Starcor Pharmaceuticals, Inc. Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia
US6607755B2 (en) * 2001-06-21 2003-08-19 Michael Donald Farley Anti-aromatase pharmaceutical composition for controlling testosterone/estrone ratios
EP1624863A1 (en) * 2003-01-13 2006-02-15 Michael Farley Improvements in or relating to anti-aromatase composition
AU2003203010A1 (en) * 2003-01-13 2004-08-13 Michael Donald Farley Improvements in or relating to anti-aromatase composition
US20120142776A1 (en) * 2009-04-09 2012-06-07 Leinwand Leslie A Methods and compositions for inducing physiological hypertrophy
GB201015079D0 (en) * 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
ITMI20111284A1 (it) 2011-07-11 2013-01-12 Giovanni Nusca Composizione farmaceutica.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2096983B1 (es) * 1970-07-23 1974-05-24 Investigations Scient Pharmace
CA1038051A (en) * 1974-06-03 1978-09-05 Reginald A. Hinton Electrostatic shielding of disc windings
EP0068055B1 (fr) * 1981-06-26 1986-04-02 P.F. Industrie Procédé d'obtention d'un extrait stable et désodorisé de sabal serrulatum antiprostatique
FR2480754A1 (fr) * 1980-04-21 1981-10-23 Fabre Sa Pierre Procede d'obtention d'un extrait stable et desodorise de sabal serrulatum antiprostatique
ES524031A0 (es) * 1983-07-11 1984-11-01 Euromed S A Procedimiento para la obtencion de extractos farmacologicamente activos de la planta de genero pygeum africanum
US4486240A (en) * 1983-07-18 1984-12-04 Sciaky Bros., Inc. Method and apparatus for heat treating
JPS60215608A (ja) * 1984-04-11 1985-10-29 Shiseido Co Ltd 養毛料
FR2605223B1 (fr) * 1986-10-20 1989-09-22 Pf Medicament Compositions therapeutiques stables a base d' huile vegetale hydrophobe et son procede de preparation
IT1203934B (it) * 1987-04-17 1989-02-23 Consiglio Nazionale Ricerche Composizioni farmaceutiche contenenti alcoli superiori per il trattamento di patologie della prostata
FR2645943B1 (fr) * 1989-04-18 1991-07-26 Ouest Produits Isolants Ste In Revetement stratifie, element thermiquement isolant pourvu d'un tel revetement

Also Published As

Publication number Publication date
EP0527101A1 (en) 1993-02-10
US5284873A (en) 1994-02-08
JPH05194250A (ja) 1993-08-03
ES2034888A1 (es) 1993-04-01

Similar Documents

Publication Publication Date Title
ES2034888B1 (es) Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata.
ES2060175T3 (es) Compuestos heterociclicos.
ES2182048T3 (es) Composicion y procedimiento para tratar plantas con sustancias quimicas exogenas.
ES2181873T3 (es) Fracciones de polifenoles del te, uso de las mismas y formulaciones que las contienen.
SE8401537D0 (sv) Forbettrade analgetiska och anti-inflammatoriska kompositioner innefattande ibuprofen och sett att anvenda dessa
Hamilton Evolving and enhanced dimensions of digital marketing strategies during contemporary scenario of COVID-19
Karioti et al. Antioxidant, anti-inflammatory potential and chemical constituents of Origanum dubium Boiss., growing wild in Cyprus
ES2132241T3 (es) Composiciones oftalmicas y metodos para su conservacion y su empleo.
AR119357A1 (es) Proceso para obtener ingredientes bioactivos, uso de proceso de extracción de agua subcrítica, ingrediente bioactivo, uso de ingredientes bioactivos y composición cosmética
Emara et al. In vitro screening for the antifungal activity of some Egyptian plant extracts against the fish pathogen Saprolegnia parasitica
Bouguemra et al. Enhancing bioactive potential by growth regulators in callus of Mentha longifolia L. leaves for anti-inflammatory and analgesic activities
Arunika et al. Antioxidant potential of Fraxinus floribunda bark extracted through various aqueous processing
AR013589A1 (es) Composicion para barra de jabon
ES2123485T3 (es) Composicion para la prevencion del envejecimiento cutaneo.
Khaleel et al. Determination of antibacterial compounds of Punica granatum peel extract by TLC direct bio-autography and GCMS analysis.
Kumar et al. Ameliorative effect of Allium cepa on oxidative stress and neuronal damage after ischemia and reperfusion-induced cerebral injury
Sasikala et al. In-vitro free radical scavenging activity studies of extracts and isolated compounds of Eugenia jambolana lam. seeds
Tafurt-García et al. Antioxidant capacity and total phenol content of Hyptis spp., P. heptaphyllum, T. panamensis, T. rhoifolia and Ocotea sp
Fournier et al. Contribution to the study of Cotula cinerea essential oil
Kolar et al. An assessment of phytochemical constituents and antioxidant potential of Delphinium malabaricum (Huth) Munz
Lee et al. Physiological Study of the Extract of Junglans nigra Shells for the Cosmeceutical Application
Kwon et al. Anti-inflammatory effect of Geranium thunbergii on lipopolysaccharide-stimulated RAW 264.7 cells
Cavalcante e Costa et al. The confrontation between ethnopharmacology and pharmacological tests of medicinal plants associated with mental and neurological disorders
Patil et al. PREPARATION AND EVALUATION OF POLYHERBAL CREAM
Baruah et al. Preliminary phyto-chemical analysis and antioxidant activities of methanol extract of Argyreia roxburghii Choisy.

Legal Events

Date Code Title Description
GC2A Exploitation certificate registered application with search report

Effective date: 19981106

FD2A Announcement of lapse in spain

Effective date: 20111209