ES2034184T3 - Esterilizacion de composiciones de estabilidad limitada. - Google Patents
Esterilizacion de composiciones de estabilidad limitada.Info
- Publication number
- ES2034184T3 ES2034184T3 ES198888300926T ES88300926T ES2034184T3 ES 2034184 T3 ES2034184 T3 ES 2034184T3 ES 198888300926 T ES198888300926 T ES 198888300926T ES 88300926 T ES88300926 T ES 88300926T ES 2034184 T3 ES2034184 T3 ES 2034184T3
- Authority
- ES
- Spain
- Prior art keywords
- range
- formulations
- drug
- concentration
- physiologically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 230000001954 sterilising effect Effects 0.000 title abstract 2
- 238000004659 sterilization and disinfection Methods 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 239000000872 buffer Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010053567 Coagulopathies Diseases 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000003139 buffering effect Effects 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 230000035602 clotting Effects 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 229940039231 contrast media Drugs 0.000 abstract 1
- 239000013583 drug formulation Substances 0.000 abstract 1
- 239000003690 nonionic contrast media Substances 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/90—In vivo diagnostic or in vivo test agent which contains an additional ingredient to reduce the toxicity or side effects of the active ingredient
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/011,016 US4863714A (en) | 1987-02-05 | 1987-02-05 | Sterilization of compositions of limited stability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2034184T3 true ES2034184T3 (es) | 1993-04-01 |
Family
ID=21748489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888300926T Expired - Lifetime ES2034184T3 (es) | 1987-02-05 | 1988-02-04 | Esterilizacion de composiciones de estabilidad limitada. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4863714A (enExample) |
| EP (1) | EP0278674B1 (enExample) |
| JP (1) | JPH0667855B2 (enExample) |
| AT (1) | ATE79279T1 (enExample) |
| AU (1) | AU607461B2 (enExample) |
| CA (1) | CA1300005C (enExample) |
| DE (1) | DE3873553T2 (enExample) |
| ES (1) | ES2034184T3 (enExample) |
| GR (1) | GR3006111T3 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8906130D0 (en) * | 1989-03-17 | 1989-05-04 | Nycomed As | Compositions |
| GB9020091D0 (en) * | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| DE4015832A1 (de) * | 1990-05-17 | 1991-11-21 | Thomae Gmbh Dr K | Verfahren zur inaktivierung der biologischen aktivitaet von dna |
| AU701724B2 (en) | 1994-07-01 | 1999-02-04 | Baxter International Inc. | Biochemically balanced peritoneal dialysis solutions |
| US5605934A (en) * | 1995-03-23 | 1997-02-25 | Baxter International Inc. | Method of manufacturing and storing solutions |
| US5972225A (en) * | 1996-05-07 | 1999-10-26 | Cook Imaging Corporation | Process for remediating endotoxin-contaminated bulk non-ionic contrast media |
| US6309673B1 (en) | 1999-09-10 | 2001-10-30 | Baxter International Inc. | Bicarbonate-based solution in two parts for peritoneal dialysis or substitution in continuous renal replacement therapy |
| US7122210B2 (en) * | 2002-01-11 | 2006-10-17 | Baxter International Inc. | Bicarbonate-based solutions for dialysis therapies |
| US7445801B2 (en) * | 2002-06-07 | 2008-11-04 | Baxter International Inc. | Stable bicarbonate-based solution in a single container |
| US20060094700A1 (en) * | 2004-11-02 | 2006-05-04 | Allergan, Inc. | Heat sterilization of a steroid in the presence of phosphate |
| US7935070B2 (en) * | 2005-01-28 | 2011-05-03 | Fresenius Medical Care North America | Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product |
| TW200914069A (en) * | 2007-05-25 | 2009-04-01 | Ajinomoto Kk | Method of producing transfusion for peripheral intravenous administration |
| CA2793277C (en) * | 2010-03-23 | 2018-09-04 | Ge Healthcare As | Preparation of stabilised x-ray diagnostic composition |
| US9585810B2 (en) | 2010-10-14 | 2017-03-07 | Fresenius Medical Care Holdings, Inc. | Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter-chamber diffuser |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224440A (en) * | 1975-05-15 | 1980-09-23 | Mallinckrodt, Inc. | 1-(3,5-Disubstituted-2,4,6-triiodophenly)-3-(polyhydroxy-alkyl)urea compounds |
| GB2031405B (en) * | 1978-07-04 | 1983-06-15 | Nyegaard & Co As | Process for the preparation of a sterile injectable physiologically acceptable solution of an x-ray contrast agent and solutions of the x-ray contrast agent and a buffer |
| NZ190907A (en) * | 1978-07-04 | 1981-10-19 | Nyegaard & Co As | Preparation of x-ray contrast agent by autoclaving a meta-carboxamido-ortho-iodo-n-(betahydroxyalkyl)-aniline |
| FR2571367B1 (fr) * | 1984-10-09 | 1987-02-13 | Guerbet Sa | Composes triaminobenzeniques iodes et/ou bromes, leur procede de preparation et leur application dans des produits de contraste |
| GB8717625D0 (en) * | 1987-07-24 | 1987-09-03 | Nycomed As | Chemical compounds |
-
1987
- 1987-02-05 US US07/011,016 patent/US4863714A/en not_active Expired - Fee Related
-
1988
- 1988-02-04 EP EP88300926A patent/EP0278674B1/en not_active Expired - Lifetime
- 1988-02-04 AT AT88300926T patent/ATE79279T1/de not_active IP Right Cessation
- 1988-02-04 ES ES198888300926T patent/ES2034184T3/es not_active Expired - Lifetime
- 1988-02-04 DE DE8888300926T patent/DE3873553T2/de not_active Expired - Lifetime
- 1988-02-04 CA CA000558096A patent/CA1300005C/en not_active Expired - Lifetime
- 1988-02-04 JP JP63022941A patent/JPH0667855B2/ja not_active Expired - Lifetime
- 1988-02-05 AU AU11336/88A patent/AU607461B2/en not_active Expired
-
1992
- 1992-10-29 GR GR920402432T patent/GR3006111T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0278674B1 (en) | 1992-08-12 |
| GR3006111T3 (enExample) | 1993-06-21 |
| EP0278674A3 (en) | 1989-07-19 |
| DE3873553T2 (de) | 1993-02-18 |
| DE3873553D1 (de) | 1992-09-17 |
| AU607461B2 (en) | 1991-03-07 |
| CA1300005C (en) | 1992-05-05 |
| JPH01221330A (ja) | 1989-09-04 |
| AU1133688A (en) | 1988-08-11 |
| ATE79279T1 (de) | 1992-08-15 |
| EP0278674A2 (en) | 1988-08-17 |
| US4863714A (en) | 1989-09-05 |
| JPH0667855B2 (ja) | 1994-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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