ES2019871B3 - 1,2,3,4,4a,9b-hexahidro-4a-aminoalquildibenzofuranos, un proceso para su preparacion y su uso como medicamentos. - Google Patents

1,2,3,4,4a,9b-hexahidro-4a-aminoalquildibenzofuranos, un proceso para su preparacion y su uso como medicamentos.

Info

Publication number
ES2019871B3
ES2019871B3 ES86117724T ES86117724T ES2019871B3 ES 2019871 B3 ES2019871 B3 ES 2019871B3 ES 86117724 T ES86117724 T ES 86117724T ES 86117724 T ES86117724 T ES 86117724T ES 2019871 B3 ES2019871 B3 ES 2019871B3
Authority
ES
Spain
Prior art keywords
hydrogen
aminoalquildibenzofuranos
hexahidro
medicines
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES86117724T
Other languages
English (en)
Inventor
Gregory Michael Shutske
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2019871B3 publication Critical patent/ES2019871B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES86117724T 1985-12-30 1986-12-19 1,2,3,4,4a,9b-hexahidro-4a-aminoalquildibenzofuranos, un proceso para su preparacion y su uso como medicamentos. Expired - Lifetime ES2019871B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/814,453 US4668690A (en) 1985-12-30 1985-12-30 1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans useful as analgesics, anticonvulsants or antidepressants

Publications (1)

Publication Number Publication Date
ES2019871B3 true ES2019871B3 (es) 1991-07-16

Family

ID=25215095

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86117724T Expired - Lifetime ES2019871B3 (es) 1985-12-30 1986-12-19 1,2,3,4,4a,9b-hexahidro-4a-aminoalquildibenzofuranos, un proceso para su preparacion y su uso como medicamentos.

Country Status (7)

Country Link
US (1) US4668690A (es)
EP (1) EP0230020B1 (es)
JP (1) JPS62215579A (es)
AT (1) ATE56713T1 (es)
DE (1) DE3674372D1 (es)
ES (1) ES2019871B3 (es)
GR (1) GR3001195T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2621917B1 (fr) * 1987-10-16 1990-03-02 Roussel Uclaf Nouveaux derives du 6, 7, 8, 9 tetrahydro 1-dibenzofurannol, leur procede de preparation et leur application comme medicaments
US5071853A (en) * 1989-03-23 1991-12-10 Bigge Christopher F Polycyclic amines useful as cerebrovascular agents
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
EP0559656A1 (en) * 1990-11-29 1993-09-15 Rhone-Poulenc Rorer International (Holdings) Inc. Process for preparing multicyclic oxy-containing ring components
US5846995A (en) * 1997-08-25 1998-12-08 Eli Lilly And Company Substituted 1, 2, 3, 4-tetrahydro-2-dibenzofuranamines and 2-amino-cyclohepta (6, 7-B) Benzofurans
BR9711273A (pt) * 1996-08-28 1999-08-17 Lilly Co Eli 1,2,3,4- Tetraidro-2-dibenzofuranaminas substituidas e 2- aminociclohepta b benzofuranos
FR2752839B1 (fr) * 1996-08-29 1998-10-09 Synthelabo Derives de benzofurane, leur preparation et leur application en therapeutique
EP1852429B1 (de) * 2006-04-25 2010-09-15 Merck Patent GmbH Hexahydro-dibenzofuranderivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1084440A (en) * 1963-12-31 1967-09-20 Upjohn Co Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof
US3496181A (en) * 1966-10-24 1970-02-17 Upjohn Co 2 - aminocycloalkyl hydroquinones,esters,ethers and n-oxides thereof,and a process for preparing the same
FR2507603A1 (fr) * 1981-06-12 1982-12-17 Cerm Cent Europ Rech Mauvernay 1, 2, 3, 4, 4a, 9b-hexahydro-4a-piperazinylmethyl-4-dibenzofuranones ou 4-dibenzofuranols substitues, procede de synthese et application en therapeutique

Also Published As

Publication number Publication date
DE3674372D1 (de) 1990-10-25
EP0230020A3 (en) 1988-08-10
EP0230020A2 (en) 1987-07-29
JPS62215579A (ja) 1987-09-22
EP0230020B1 (en) 1990-09-19
ATE56713T1 (de) 1990-10-15
GR3001195T3 (en) 1992-06-30
US4668690A (en) 1987-05-26

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