ES2019839A6 - Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica. - Google Patents

Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica.

Info

Publication number
ES2019839A6
ES2019839A6 ES9001306A ES9001306A ES2019839A6 ES 2019839 A6 ES2019839 A6 ES 2019839A6 ES 9001306 A ES9001306 A ES 9001306A ES 9001306 A ES9001306 A ES 9001306A ES 2019839 A6 ES2019839 A6 ES 2019839A6
Authority
ES
Spain
Prior art keywords
derivatives
polyphosphorylated
galactopyranosides
activity
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9001306A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Espana SA
Original Assignee
Europharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europharma SA filed Critical Europharma SA
Priority to ES9001306A priority Critical patent/ES2019839A6/es
Priority to DE69022033T priority patent/DE69022033D1/de
Priority to DE199090500129T priority patent/DE456948T1/de
Priority to EP90500129A priority patent/EP0456948B1/en
Priority to AT90500129T priority patent/ATE127125T1/de
Priority to IE049191A priority patent/IE910491A1/en
Priority to PT97624A priority patent/PT97624B/pt
Publication of ES2019839A6 publication Critical patent/ES2019839A6/es
Priority to GR92300068T priority patent/GR920300068T1/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS POLIFOSFORILADOS DE GALACTOSA CON ACTIVIDAD INSULINICA EN EL QUE, EN UNA PRIMERA ETAPA, SE REALIZA UNA FOSFITILACION DE ALQUIL *FORMULA* D-GALACTOPIRANOSIDOS O DE DERIVADOS SUYOS PARCIALMENTE PROTEGIDOS QUE CONTIENEN DOS O TRES GRUPOS HIDROXILOS LIBRES; EN UNA SEGUNDA ETAPA, LOS DERIVADOS PARCIALMENTE FOSFITILADOS ASI OBTENIDOS SE SOMETEN A UNA OXIDACION PARA DAR LOS DERIVADOS PARCIALMENTE FOSFATADOS QUE EN LA TERCERA ETAPA SE DESBLOQUEAN PARA DAR LOS CORRESPONDIENTES FOSFATOS LIBRES QUE SE AISLAN EN FORMA DE SAL SODICA.
ES9001306A 1990-05-10 1990-05-10 Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica. Expired - Lifetime ES2019839A6 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES9001306A ES2019839A6 (es) 1990-05-10 1990-05-10 Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica.
DE69022033T DE69022033D1 (de) 1990-05-10 1990-12-28 Verfahren zur Herstellung von polyphosphorylierten Galaktopyranosidderivaten mit insulinähnlicher Potenz.
DE199090500129T DE456948T1 (de) 1990-05-10 1990-12-28 Verfahren zur herstellung von polyphosphorylierten galaktopyranosidderivaten mit insulinaehnlicher potenz.
EP90500129A EP0456948B1 (en) 1990-05-10 1990-12-28 Method for the preparation of polyphosphorylated derivatives of galactopyranosides with a potential insulin-like activity
AT90500129T ATE127125T1 (de) 1990-05-10 1990-12-28 Verfahren zur herstellung von polyphosphorylierten galaktopyranosidderivaten mit insulinähnlicher potenz.
IE049191A IE910491A1 (en) 1990-05-10 1991-02-13 Method for the preparation of polyphosphorylated derivatives¹of galactopyranosides with a potential insulin-like activity
PT97624A PT97624B (pt) 1990-05-10 1991-05-09 Processo para a preparacao de derivados de galactopiranosidos fosforilados com uma actividade potencial identica a da insulina
GR92300068T GR920300068T1 (en) 1990-05-10 1992-08-31 Method for the preparation of polyphosphorylated derivatives of galactopyranosides with a potential insulin-like activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9001306A ES2019839A6 (es) 1990-05-10 1990-05-10 Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica.

Publications (1)

Publication Number Publication Date
ES2019839A6 true ES2019839A6 (es) 1991-07-01

Family

ID=8267236

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9001306A Expired - Lifetime ES2019839A6 (es) 1990-05-10 1990-05-10 Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica.

Country Status (7)

Country Link
EP (1) EP0456948B1 (es)
AT (1) ATE127125T1 (es)
DE (2) DE456948T1 (es)
ES (1) ES2019839A6 (es)
GR (1) GR920300068T1 (es)
IE (1) IE910491A1 (es)
PT (1) PT97624B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665080A (ja) * 1992-03-10 1994-03-08 Godo Shiyusei Kk α−グルコシダ−ゼ阻害剤を含有する、過血糖付随疾患の予防・治療剤、および保健食
SE9403137D0 (sv) * 1994-09-20 1994-09-20 Perstorp Ab Derivatives of carbohydrates and compositions containing them
WO2012045009A2 (en) * 2010-09-30 2012-04-05 Normoxys, Inc. Polyphosphate and pyrophosphate derivative of saccharides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8302353A (nl) * 1983-07-01 1985-02-01 Stichting Katholieke Univ Fosforyleringsmiddel; werkwijze voor het bereiden daarvan; werkwijze voor het fosforyleren van een organische hydroxyl- of amineverbinding.
US4873355A (en) * 1987-05-29 1989-10-10 E. I. Du Pont De Nemours And Company Process for regioselectively preparing phosphorylated inositols and other cyclitols
EP0354323A3 (en) * 1988-08-12 1990-06-13 American Cyanamid Company Antidiabetic phosphates

Also Published As

Publication number Publication date
ATE127125T1 (de) 1995-09-15
GR920300068T1 (en) 1992-08-31
PT97624B (pt) 1998-08-31
EP0456948A2 (en) 1991-11-21
IE910491A1 (en) 1991-11-20
EP0456948B1 (en) 1995-08-30
DE69022033D1 (de) 1995-10-05
PT97624A (pt) 1992-02-28
EP0456948A3 (en) 1992-07-29
DE456948T1 (de) 1992-05-21

Similar Documents

Publication Publication Date Title
CS151187A2 (en) Method of carbacycline derivatives' cyclodextrin's clathrates production
HU905862D0 (en) Process for producing epy-podophyllotoxin-glycoside-4'phosphate derivatives
BG40814A3 (en) Method for preparing nucleozides
CS900287A2 (en) Method of phosphinic acid's derivatives production
KR840004761A (ko) N-글리코실화 카복스아미드 유도체의 제조방법
AU9175482A (en) Method of producing printed circuits
CS242188A2 (en) Method of 6-substituted 2,3-dideoxynucleosides production
BG37991A3 (en) Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic
ES2019839A6 (es) Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica.
FR2575466B1 (fr) Nouveaux complexes de silicium hexacoordines, leur procede de preparation et leur application
AU1567383A (en) Lyophilized skeletal imaging composition
BE888562A (fr) Procede de production d'une preparation enzymatique de fructosyl-transferase,
HU183533B (en) Process for producing aquous bitumen-composition
GB2214914B (en) Method for production of glucose by use of transglucosidase
IE822448L (en) Stereospecific synthesis
ZA776519B (en) Process for the production of 9-(b-d-arabinofuranosyl)adenine,5'-phosphate
DE3160637D1 (en) Synthesis of deazapurine nucleosides
SE8504657D0 (sv) Nya 5-fluor-2'-deoxiuridinderivat och slater derav, forfarande for deras framstellning och antitumormedel innehallande dessa
SU1178325A3 (ru) "cпocoб пoлучehия пpoизboдhыx 2,2-диaлkил-18,19-диhopпpeгh-4-eh-3,20-диoha"
YU109684A (en) Process for making derivatives of bicyclo-(3,2,1)-octancarboxylic acid
EP0173753A4 (en) 6-SUBSTITUTED PROSTAGLANDINE E 1 AND THEIR PRODUCTION.
AU7699181A (en) Vibration assisted sluices
AU2148899A (en) 15-methyl-cyclopropanosteroids and method for the production thereof
AU2196188A (en) 1(2h)-phthalazinones as cytoprotective agents
DE3562898D1 (en) Process for the working-up of slightly water soluble substituted 1,3 diols

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990301