ES2012007A6 - Metodo para la purificacion de un agente biologicamente activo. - Google Patents

Metodo para la purificacion de un agente biologicamente activo.

Info

Publication number
ES2012007A6
ES2012007A6 ES8901827A ES8901827A ES2012007A6 ES 2012007 A6 ES2012007 A6 ES 2012007A6 ES 8901827 A ES8901827 A ES 8901827A ES 8901827 A ES8901827 A ES 8901827A ES 2012007 A6 ES2012007 A6 ES 2012007A6
Authority
ES
Spain
Prior art keywords
freeze
polar solvent
factor
purification
dried product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8901827A
Other languages
English (en)
Inventor
Fred I Chasalow
H Leon Bradlow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Long Island Jewish Medical Center
Original Assignee
Long Island Jewish Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Long Island Jewish Medical Center filed Critical Long Island Jewish Medical Center
Publication of ES2012007A6 publication Critical patent/ES2012007A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)

Abstract

METODO PARA LA PURIFICACION DE UN AGENTE BIOLOGICAMENTE ACTIVO. EL METODO SE CARACTERIZA POR COMPRENDER: AGITAR EL FLUIDO CISTICO DE SENOS FEMENINOS, TIPO 1, CON UN PRIMER DISOLVENTE POLAR, DESCARTAR EL PRECIPITADO; MEZCLAR EL FACTOR SOLUBILIZADO CON UN SEGUNDO DISOLVENTE POLAR, Y RECUPERAR UNA FASE ORGANICA QUE CONTIENE DICHO FACTOR; SIENDO DICHO SEGUNDO DISOLVENTE POLAR MENOS POLAR QUE EL PRIMER DISOLVENTE; SEPARAR EL SEGUNDO DISOLVENTE POLAR DE DICHA FASE ORGANICA; LIOFILIZAR LA FASE ACUOSA; EXTRAER EL LIOFILIZADO CON UNA MEZCLA DE METANOL-AGUA; EXTRAER EL LIOFILIZADO CON UNA MEZCLA DE METANOL-AGUA; SOMETER EL LIOFILIZADO EXTRAIDO A CROMATOGRAFIA POR AFINIDAD HIDROFOBA; Y RECUPERAR LAS FRACCIONES QUE CONTIENEN DICHO FACTOR.
ES8901827A 1986-12-09 1987-12-09 Metodo para la purificacion de un agente biologicamente activo. Expired - Lifetime ES2012007A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93955286A 1986-12-09 1986-12-09

Publications (1)

Publication Number Publication Date
ES2012007A6 true ES2012007A6 (es) 1990-02-16

Family

ID=25473370

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8901827A Expired - Lifetime ES2012007A6 (es) 1986-12-09 1987-12-09 Metodo para la purificacion de un agente biologicamente activo.
ES8703511A Expired ES2009501A6 (es) 1986-12-09 1987-12-09 Metodo para la purificacion de un agente biologicamente activo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES8703511A Expired ES2009501A6 (es) 1986-12-09 1987-12-09 Metodo para la purificacion de un agente biologicamente activo.

Country Status (6)

Country Link
KR (1) KR890700027A (es)
AR (1) AR247098A1 (es)
ES (2) ES2012007A6 (es)
HU (1) HU201874B (es)
IL (1) IL84745A (es)
ZA (1) ZA879256B (es)

Also Published As

Publication number Publication date
IL84745A0 (en) 1988-05-31
AR247098A1 (es) 1994-11-30
KR890700027A (ko) 1989-03-02
ZA879256B (en) 1988-08-31
HU201874B (en) 1991-01-28
IL84745A (en) 1992-12-01
ES2009501A6 (es) 1989-10-01

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