ES2011186A6 - Procedimiento para la preparacion de composiciones farmaceuticas conteniendo moxonidina, hidroclotiazida, con o sin triamteren. - Google Patents

Procedimiento para la preparacion de composiciones farmaceuticas conteniendo moxonidina, hidroclotiazida, con o sin triamteren.

Info

Publication number
ES2011186A6
ES2011186A6 ES8803579A ES8803579A ES2011186A6 ES 2011186 A6 ES2011186 A6 ES 2011186A6 ES 8803579 A ES8803579 A ES 8803579A ES 8803579 A ES8803579 A ES 8803579A ES 2011186 A6 ES2011186 A6 ES 2011186A6
Authority
ES
Spain
Prior art keywords
pharmaceutical products
chloro
phenylpteridine
moxonidine
benzothiadiazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8803579A
Other languages
English (en)
Inventor
Ben Armah
Wolfgang Stenzel
Vera Planitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of ES2011186A6 publication Critical patent/ES2011186A6/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPOSICIONES FARMACEUTICAS CONTENIENDO MOXONIDINA, HIDROCLOROTIAZIDA, CON O SIN TRIAMTEREN. PROCEDIMIENTO PARA LA PREPARACION DE COMPOSICIONES FARMACEUTICAS CONTENIENDO MOXONIDINA [4-CLORO-6-METOXI-2-METIL-5-(2-IMIDAZOLIN)-2-IL) AMINOPIRIDINA] O SUS SALES FARMACEUTICAMENTE EQUIVALENTES, E HIDROCLOROTIAZIDA (6-CLORO-3,4-DIHIDRO-2H-1,2,4-BENZOTIADIAZINA-7-SULFONAMIDA-1,1-DIOXIDO), CON O SIN TRIAMTEREN (2,4,7-TRIAMINO-6-FENILPTERIDINA). EL PROCEDIMIENTO CONSISTE EN HUMEDECER LA HIDROCLOROTIAZIDA, Y EVENTUALMENTE EL TRIAMTEREN, CON UNA SOLUCION DE MOXONIDINA, O UNA DE SUS SALES, EN UN DISOLVENTE ADECUADO, CON APORTE DE CALOR, PARA LOGRAR OBTENER UN GRANULADO, QUE SECA Y SE TRITURA. ESTE PRODUCTO TRITURADO PUEDE UTILIZARSE DIRECTAMENTE PARA LLENAR CAPSULAS, O PUEDE UTILIZARSE, CON LA ADICION DE LOS COADYUVANTES NECESARIOS, PARA PREPARAR COMPRIMIDOS POR PRESION. LOS PRODUCTOS OBTENIDOS TIENEN UNA VALIOSA APLICACION COMO DIURETICOS Y ANTIHIPERINTENSIVOS.
ES8803579A 1987-11-24 1988-11-23 Procedimiento para la preparacion de composiciones farmaceuticas conteniendo moxonidina, hidroclotiazida, con o sin triamteren. Expired ES2011186A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873739779 DE3739779A1 (de) 1987-11-24 1987-11-24 Pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
ES2011186A6 true ES2011186A6 (es) 1989-12-16

Family

ID=6341139

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8803579A Expired ES2011186A6 (es) 1987-11-24 1988-11-23 Procedimiento para la preparacion de composiciones farmaceuticas conteniendo moxonidina, hidroclotiazida, con o sin triamteren.

Country Status (9)

Country Link
US (1) US4952410A (es)
EP (1) EP0317855B1 (es)
JP (1) JPH01193224A (es)
KR (1) KR890007740A (es)
AT (1) ATE70445T1 (es)
AU (1) AU2566288A (es)
DE (2) DE3739779A1 (es)
ES (1) ES2011186A6 (es)
ZA (1) ZA888818B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
US5977121A (en) * 1995-02-28 1999-11-02 Eli Lilly And Company Use of moxonidine for the treatment of atherosclerosis
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
CA2182851A1 (en) * 1995-08-15 1997-02-16 August Masaru Watanabe Method for treating substance abuse withdrawal
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
AU9692898A (en) * 1997-10-17 1999-05-10 Eli Lilly And Company Potentiation of pharmaceuticals
WO2000044355A1 (en) * 1999-01-29 2000-08-03 Eli Lilly And Company Moxonidine salts
TR200102221T2 (tr) * 1999-02-01 2002-01-21 Solvay Pharmaceuticals Gmbh Kalp krizi sonrası tedavileri için moksonidin kullanımı
AU2003257418A1 (en) * 2002-06-19 2004-01-06 Solvay Pharmaceuticals Gmbh Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins
CN104511127B (zh) * 2013-09-30 2018-08-24 浙江宇安消防装备有限公司 一种d类火灾的灭火剂及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081230A (en) * 1960-09-08 1963-03-12 Smith Kline French Lab Diuretic and antihypertensive triaminoarylpteridines
US3113075A (en) * 1960-10-17 1963-12-03 Merck & Co Inc Heterocyclic compounds
US3449496A (en) * 1965-12-08 1969-06-10 Smithkline Corp Compositions and method for treating hypertensive patients comprising hydrochlorothiazide triamterene and reserpine
US4075335A (en) * 1972-08-24 1978-02-21 Ciba-Geigy Corporation Pharmaceutical piperidine derivatives
US4323570A (en) * 1978-11-15 1982-04-06 Beiersdorf Aktiengesellschaft Substituted aminopyrimidines
AU531659B2 (en) * 1979-03-22 1983-09-01 Goedecke Aktiengesellschaft (+)-(3-methyl-4-oxo - 5n-piperidinothiazolidin-2-ylidene) acetic acid esters
US4681765A (en) * 1984-09-13 1987-07-21 American Home Products Corporation Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
DE3517820A1 (de) * 1985-05-17 1986-11-20 Röhm Pharma GmbH, 6108 Weiterstadt Pharmazeutische praeparate mit antihypertensiver und kardioprotektiver wirkung
US4793999A (en) * 1987-03-27 1988-12-27 Sheth Prabhakar R Method of manufacturing an antihypertensive, diuretic and antihypokalemic pharmaceutical composition with polyethylene glycol

Also Published As

Publication number Publication date
DE3867042D1 (de) 1992-01-30
US4952410A (en) 1990-08-28
EP0317855B1 (de) 1991-12-18
JPH01193224A (ja) 1989-08-03
ZA888818B (en) 1989-08-30
ATE70445T1 (de) 1992-01-15
EP0317855A3 (en) 1990-05-02
KR890007740A (ko) 1989-07-05
EP0317855A2 (de) 1989-05-31
AU2566288A (en) 1989-05-25
DE3739779A1 (de) 1989-06-08

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