ES2009207A6 - Procedimiento para la obtencion de un sustrato cuya superficie presenta actividad antitrombogenica. - Google Patents

Procedimiento para la obtencion de un sustrato cuya superficie presenta actividad antitrombogenica.

Info

Publication number
ES2009207A6
ES2009207A6 ES8600180A ES8600180A ES2009207A6 ES 2009207 A6 ES2009207 A6 ES 2009207A6 ES 8600180 A ES8600180 A ES 8600180A ES 8600180 A ES8600180 A ES 8600180A ES 2009207 A6 ES2009207 A6 ES 2009207A6
Authority
ES
Spain
Prior art keywords
substrate
surface presenting
antithrombogenic activity
antithrombogenic
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600180A
Other languages
English (en)
Inventor
Daniel Bichon
Michel Schneider
Christian Guillot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Battelle Memorial Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute Inc filed Critical Battelle Memorial Institute Inc
Publication of ES2009207A6 publication Critical patent/ES2009207A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN SUSTRATO CUYA SUPERFICIE PRESENTA ACTIVIDAD ANTITROMBOGENICA. COMPRENDE REVESTIR UN ARTICULO SELECCIONADO DE UNA CAPA DELGADA DE UNA MEZCLA DE MONOMEROS FOTOPOLIMERIZABLES Y QUE CONTENGAN UN FOTOINICIADOR; PROCEDER A SU FOTOPOLIMERIZACION POR IRRADIACION; Y A CONTINUACION, CUANDO LA PELICULA HA ADQUIRIDO EL GRADO DE ENDURECIMIENTO DESEADO, SE LE ENLAZA CON UN DERIVADO DE HEPARINA POR INTERMEDIO DE UNA DIAMINA DE PUENTE DE FORMULA H2N(CH2)N -NH2- CON EL FIN DE REALIZAR UN ESLABON DE PUENTEO, CUYO ESLABON PERMITE ASEGURAR EL ENLACE ENTRE EL COPOLIMERO Y EL FRAGMENTO DE HEPARINA.
ES8600180A 1985-07-08 1986-07-08 Procedimiento para la obtencion de un sustrato cuya superficie presenta actividad antitrombogenica. Expired ES2009207A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2954/85A CH665954A5 (fr) 1985-07-08 1985-07-08 Substrat dont la surface presente une activite antithrombogenique.

Publications (1)

Publication Number Publication Date
ES2009207A6 true ES2009207A6 (es) 1989-09-16

Family

ID=4245380

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600180A Expired ES2009207A6 (es) 1985-07-08 1986-07-08 Procedimiento para la obtencion de un sustrato cuya superficie presenta actividad antitrombogenica.

Country Status (7)

Country Link
US (1) US4987181A (es)
EP (1) EP0228387B1 (es)
JP (1) JPS63500079A (es)
CA (1) CA1292687C (es)
CH (1) CH665954A5 (es)
ES (1) ES2009207A6 (es)
WO (1) WO1987000060A1 (es)

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SE470006B (sv) * 1991-09-26 1993-10-25 Corline Systems Ab Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
US5344455A (en) * 1992-10-30 1994-09-06 Medtronic, Inc. Graft polymer articles having bioactive surfaces
US5308641A (en) * 1993-01-19 1994-05-03 Medtronic, Inc. Biocompatibility of solid surfaces
US5558900A (en) * 1994-09-22 1996-09-24 Fan; You-Ling One-step thromboresistant, lubricious coating
US5532311A (en) * 1995-02-01 1996-07-02 Minnesota Mining And Manufacturing Company Process for modifying surfaces
US5583213A (en) * 1995-05-12 1996-12-10 Minnesota Mining And Manufacturing Company Process to activate sulfated polysaccharides
US5620738A (en) * 1995-06-07 1997-04-15 Union Carbide Chemicals & Plastics Technology Corporation Non-reactive lubicious coating process
US5731087A (en) * 1995-06-07 1998-03-24 Union Carbide Chemicals & Plastics Technology Corporation Lubricious coatings containing polymers with vinyl and carboxylic acid moieties
US7045585B2 (en) * 1995-11-30 2006-05-16 Hamilton Civic Hospital Research Development Inc. Methods of coating a device using anti-thrombin heparin
US6491965B1 (en) 1995-11-30 2002-12-10 Hamilton Civic Hospitals Research Development, Inc. Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US6562781B1 (en) * 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US6146771A (en) * 1997-07-01 2000-11-14 Terumo Cardiovascular Systems Corporation Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine
US6197289B1 (en) 1997-07-01 2001-03-06 Terumo Cardiovascular Systems Corporation Removal of biologically active agents
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
US7005513B1 (en) 1999-04-02 2006-02-28 Netech, Inc. Functionalized glycosaminoglycan polymer and medical instruments and drugs by using the same
US6695817B1 (en) 2000-07-11 2004-02-24 Icu Medical, Inc. Medical valve with positive flow characteristics
US6797743B2 (en) * 2000-09-27 2004-09-28 Michigan Biotechnology Institute Antimicrobial polymer
US20050043506A1 (en) * 2000-09-27 2005-02-24 Michigan Biotechnology Institute Polyamide materials based on unsaturated carboxylic acids and amines
US6495657B1 (en) * 2000-10-27 2002-12-17 Michigan Biotechnology Institute Two dimensional polyamides prepared from unsaturated carboxylic acids and amines
US6509104B2 (en) * 2000-12-05 2003-01-21 Michigan Biotechnology Institute Antithrombogenic polymer coating
US8101196B2 (en) 2001-06-26 2012-01-24 Biointeractions, Ltd. Polysaccharide biomaterials and methods of use thereof
US6939554B2 (en) * 2002-02-05 2005-09-06 Michigan Biotechnology Institute Antimicrobial polymer
AU2003220363A1 (en) 2002-03-20 2003-10-08 Michigan Biotechnology Institute Conductive polymer-based material
US6951902B2 (en) * 2002-08-16 2005-10-04 Michigan Biotechnology Institute Two dimensional polymer that generates nitric oxide
WO2006052655A2 (en) 2004-11-05 2006-05-18 Icu Medical, Inc. Soft-grip medical connector
CA2839795A1 (en) * 2005-12-08 2007-12-13 The Polymer Technology Group Incorporated Self-assembling monomers and oligomers as surface-modifying endgroups for polymers
JP5015258B2 (ja) 2006-10-25 2012-08-29 アイシーユー・メディカル・インコーポレーテッド 医療用コネクタ
WO2008150788A1 (en) * 2007-05-30 2008-12-11 The Polymer Technology Group Incorporated Polymers with bio-functional self assembling monolayer endgroups for therapeutic applications and blood filtration
CA2725103C (en) * 2008-05-29 2016-05-24 Dsm Ip Assets B.V. Antimicrobial polymers and their uses
US8454579B2 (en) 2009-03-25 2013-06-04 Icu Medical, Inc. Medical connector with automatic valves and volume regulator
USD644731S1 (en) 2010-03-23 2011-09-06 Icu Medical, Inc. Medical connector
US8758306B2 (en) 2010-05-17 2014-06-24 Icu Medical, Inc. Medical connectors and methods of use
CN102811749B (zh) * 2010-06-16 2015-05-27 泰尔茂株式会社 医疗用具的制造方法
US9567357B2 (en) 2011-06-24 2017-02-14 Biointeractions Ltd. Biocompatible, biomimetic ampholyte materials
WO2014112956A1 (en) 2013-01-17 2014-07-24 Center Odličnosti Polimerni Marteriali In Tehnologije Method for treatment of a vascular graft
JP6454325B2 (ja) 2013-04-26 2019-01-16 バイオインタラクションズ・リミテッドＢｉｏＩｎｔｅｒａｃｔｉｏｎｓ Ｌｔｄ 生物活性被覆
USRE49528E1 (en) 2013-04-26 2023-05-16 Biointeractions Ltd. Bioactive coatings
WO2015088862A1 (en) 2013-12-11 2015-06-18 Icu Medical, Inc. Check valve
USD786427S1 (en) 2014-12-03 2017-05-09 Icu Medical, Inc. Fluid manifold
USD793551S1 (en) 2014-12-03 2017-08-01 Icu Medical, Inc. Fluid manifold

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US3826678A (en) * 1972-06-06 1974-07-30 Atomic Energy Commission Method for preparation of biocompatible and biofunctional materials and product thereof
US4526714A (en) * 1982-12-13 1985-07-02 Cordis Europa N.V. Conjugates of anticoagulant and protein
SE8200751L (sv) * 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
US4521564A (en) * 1984-02-10 1985-06-04 Warner-Lambert Company Covalent bonded antithrombogenic polyurethane material
US4720512A (en) * 1986-03-24 1988-01-19 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity

Also Published As

Publication number Publication date
JPS63500079A (ja) 1988-01-14
WO1987000060A1 (fr) 1987-01-15
CH665954A5 (fr) 1988-06-30
EP0228387B1 (fr) 1989-04-05
US4987181A (en) 1991-01-22
CA1292687C (fr) 1991-12-03
EP0228387A1 (fr) 1987-07-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980504