ES2001540A6 - Procedimiento de preparacion de fenil-(3-hexametilenoiminopropil)-cetona y sus sales de adicion - Google Patents

Procedimiento de preparacion de fenil-(3-hexametilenoiminopropil)-cetona y sus sales de adicion

Info

Publication number
ES2001540A6
ES2001540A6 ES8601182A ES8601182A ES2001540A6 ES 2001540 A6 ES2001540 A6 ES 2001540A6 ES 8601182 A ES8601182 A ES 8601182A ES 8601182 A ES8601182 A ES 8601182A ES 2001540 A6 ES2001540 A6 ES 2001540A6
Authority
ES
Spain
Prior art keywords
phenyl
ketone
hexamethylene
iminopropyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601182A
Other languages
English (en)
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Priority to ES8601182A priority Critical patent/ES2001540A6/es
Publication of ES2001540A6 publication Critical patent/ES2001540A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE LA FENIL-(3-HEXAMETILENOIMINOPROPIL)-CETONA Y SUS SALES DE ADICION, UTILES EN TERAPEUTICA COMO AGENTES VASODILATADORES, QUE BASICAMENTE CONSISTE EN HACER REACCIONAR EL 4-HEXAMETILENOIMINO-BUTIRONITRILO CON EL BROMURO DE FENIL MAGNESIO.
ES8601182A 1985-07-10 1986-07-09 Procedimiento de preparacion de fenil-(3-hexametilenoiminopropil)-cetona y sus sales de adicion Expired ES2001540A6 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES8601182A ES2001540A6 (es) 1985-07-10 1986-07-09 Procedimiento de preparacion de fenil-(3-hexametilenoiminopropil)-cetona y sus sales de adicion

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8510551A FR2584715B1 (fr) 1985-07-10 1985-07-10 Phenyl-(3-hexamethyleneiminopropyl)-cetone, procede de preparation et utilisation en therapeutique
ES8601182A ES2001540A6 (es) 1985-07-10 1986-07-09 Procedimiento de preparacion de fenil-(3-hexametilenoiminopropil)-cetona y sus sales de adicion

Publications (1)

Publication Number Publication Date
ES2001540A6 true ES2001540A6 (es) 1988-06-01

Family

ID=9321150

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601182A Expired ES2001540A6 (es) 1985-07-10 1986-07-09 Procedimiento de preparacion de fenil-(3-hexametilenoiminopropil)-cetona y sus sales de adicion

Country Status (14)

Country Link
US (1) US4758560A (es)
EP (1) EP0210904B1 (es)
JP (1) JPS6212769A (es)
AT (1) ATE46153T1 (es)
AU (1) AU592809B2 (es)
CA (1) CA1264322A (es)
DE (1) DE3665458D1 (es)
DK (1) DK156438C (es)
ES (1) ES2001540A6 (es)
FR (1) FR2584715B1 (es)
GR (1) GR861796B (es)
IE (1) IE59272B1 (es)
PT (1) PT82951B (es)
ZA (1) ZA865153B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8604031B2 (en) 2006-05-18 2013-12-10 Mannkind Corporation Intracellular kinase inhibitors
US7858666B2 (en) 2007-06-08 2010-12-28 Mannkind Corporation IRE-1α inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB682161A (en) * 1948-10-19 1952-11-05 Wellcome Found Improvements in and relating to the preparation of substituted amino ketones and derivatives thereof
GB1213963A (en) * 1968-03-28 1970-11-25 Richter Gedeon Vegyeszet Aromatic amino ketones
FR2092133B1 (es) * 1970-05-06 1974-03-22 Orsymonde
US3922266A (en) * 1972-06-28 1975-11-25 Sumitomo Chemical Co Aryl ketones and production thereof
DE3019497A1 (de) * 1980-05-22 1981-11-26 Bayer Ag, 5090 Leverkusen Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
FR2534916B1 (fr) * 1982-10-26 1985-11-22 Lafon Labor Nouveaux derives de phenyl-(3-aminopropyl)-cetone, utilisation en therapeutique et procede de preparation

Also Published As

Publication number Publication date
EP0210904A1 (fr) 1987-02-04
PT82951B (pt) 1989-01-30
FR2584715B1 (fr) 1987-10-09
US4758560A (en) 1988-07-19
PT82951A (fr) 1986-08-01
GR861796B (en) 1986-11-11
IE59272B1 (en) 1994-02-09
CA1264322A (en) 1990-01-09
DK326286A (da) 1987-01-11
EP0210904B1 (fr) 1989-09-06
JPS6212769A (ja) 1987-01-21
IE861823L (en) 1987-01-10
FR2584715A1 (fr) 1987-01-16
DK156438B (da) 1989-08-21
AU592809B2 (en) 1990-01-25
DK156438C (da) 1990-01-15
DE3665458D1 (en) 1989-10-12
ZA865153B (en) 1987-03-25
AU5987586A (en) 1987-01-15
DK326286D0 (da) 1986-07-09
ATE46153T1 (de) 1989-09-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040503